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. 1967 Jan;102(1):373–380. doi: 10.1042/bj1020373

The incorporation of long-chain fatty acids into phospholipids of respiring slices of rat cerebrum

G R Webster 1
PMCID: PMC1270249  PMID: 6030296

Abstract

1. Respiring slices of adult rat cerebrum have been shown to incorporate long-chain 14C-labelled fatty acids into phospholipid. 2. Labelling was almost entirely confined to lecithin and ethanolamine phospholipid, only traces being present in serine phospholipid. 3. Palmitic acid, oleic acid and linoleic acid were incorporated more actively into lecithin than into ethanolamine phospholipid, but the converse was found with stearic acid. 4. All four acids labelled the 1- and 2-positions of both lipids; palmitic acid, oleic acid and linoleic acid were approximately evenly distributed, but stearic acid was incorporated predominantly at the 1-position. 5. It is considered that incorporation is most likely brought about through acylation of endogenously derived lysophosphatides. 6. The possible implications of this pathway of lipid metabolism in nervous tissue are discussed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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