Abstract
1. The enzyme from guinea-pig liver that degrades pyridine-haemochromogen into formylbiliverdin, a possible precursor of biliverdin, breaks the porphyrin ring exclusively at the α-methene bridge. The enzyme is therefore appropriately named haem α-methenyl oxygenase. 2. It is deduced that this enzyme plays an essential role in haemoglobin catabolism in vivo.
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Selected References
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