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. 1967 Jul;104(1):122–127. doi: 10.1042/bj1040122

Fractionation of neurophysin by molecular-sieve and ion-exchange chromatography

M D Hollenberg 1, D B Hope 1
PMCID: PMC1270552  PMID: 6035504

Abstract

Neurophysin has been separated into seven distinct protein fractions. One of these components had no hormone-binding activity. The fractions that had hormone-binding activity were similar in amino acid composition: their cystine content was in the range 11·5–14·5%. The major component, neurophysin-M, was distinguished from the protein isolated by van Dyke by the presence of methionine and the absence of histidine. Neurophysin-M binds both oxytocin and vasopressin with similar affinities.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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