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. 2025 Dec 17;20(12):e0336918. doi: 10.1371/journal.pone.0336918

Factors associated with violent offenders with mental illness in forensic psychiatric evaluations

Chia-Heng Lin 1,2, Wen-Ching Hsieh 3, Li-Ting Lin 4,5, Chia-Hsiang Chan 4,5,6,*
Editor: Vincenzo De Luca7
PMCID: PMC12711024  PMID: 41406094

Abstract

Purpose

The overall crime rate among individuals with severe mental illnesses is similar to that of the general population, although some studies suggest a higher risk of violent crime among this group. Empirical research on factors associated with violent crime among individuals with mental illnesses in East Asia remains limited.

Methods

This study examined 648 offenders referred for forensic psychiatric evaluation by the criminal justice system to explore the relationship between severe mental illness, substance-related and addictive disorders, and violent crime. Demographic, clinical, forensic, and both static and dynamic factors were analyzed using bivariate analysis and multivariate logistic regression. We also tested the moderating effects of gender, history of violent crime, poor treatment adherence, and comorbid substance-related and addictive disorders on the association between severe mental illness and violent crime.

Results

The results showed that violent offenders were more likely to be male and to have never undergone a psychiatric evaluation prior to the offense, compared to non-violent offenders. Severe mental illness, substance-related and addictive disorders, single status, unemployment, and poor treatment adherence were not significantly associated with violent crime. Furthermore, gender, poor treatment adherence, a history of violent crime, and comorbid substance-related and addictive disorders did not significantly moderate the relationship between severe mental illness and violent crime.

Conclusion

These findings emphasize that individuals with severe mental illness should not be automatically linked to violent offending. A comprehensive evaluation of offenders with severe mental illness is crucial, alongside a deeper understanding of their treatment and reintegration needs.

1. Introduction

At the start of the 21st century, the World Health Organization (WHO) highlighted the critical role of mental health. Approximately 25% of the global population will experience a mental illness at some point in their lives. However, stigma remains a significant barrier, often preventing affected individuals from receiving proper treatment, obtaining stable housing, and securing employment [1].

Film and television frequently depict individuals with mental illness as irrational, dangerous, or fundamentally flawed. The media also disproportionately reports on crimes committed by those with severe mental illness, further shaping public perceptions [2,3]. Common stereotypes include the belief that mental illness is a personal choice, that affected individuals are undeserving of sympathy, lack self-control, or are incapable of making independent decisions [4,5]. These misconceptions fuel stigma and perpetuate harmful narratives about mental illness.

Assessing the risk factors for criminal behavior in individuals with mental illness requires consideration of not only active psychiatric symptoms [6] but also substance use, socioeconomic status, and environmental factors [7]. Furthermore, when evaluating the risk of violent crime in this population [8], factors such as gender, history of violent crime, illicit substance and alcohol use, treatment adherence, and psychiatric diagnosis type must also be considered.

Fazel and his research team conducted a meta-analysis of studies from English-speaking countries, using schizophrenia as a case study [9]. Their findings indicate that individuals with schizophrenia have an odds ratio (OR) of 4.0 for violent offenses compared to the general population under a random-effects model (95% confidence interval [CI] = 3.0–5.3), with high heterogeneity (I² = 88%, 95% CI = 78–91%). Even after adjusting for socioeconomic factors, the OR remained at 3.8 (95% CI = 2.6–5.0), although heterogeneity remained high (I² = 84%, 95% CI = 74–90%). The violent crimes analyzed in this study included homicide, attempted homicide, aggravated assault, sexual offenses, robbery, intimidation, unlawful detention, battery, arson, and domestic violence. However, in Western countries, the likelihood of an individual with schizophrenia committing homicide is approximately 0.01% annually, while the probability of any violent crime is approximately 0.6% per year [10]. Some clinical psychiatrists argue that individuals with schizophrenia are more often involved in legally defined minor assaultive behaviors than in severe violent crimes [11,12]. These behaviors are frequently linked to situational disputes, personality traits, or substance use, with treatment adherence also playing a crucial role [11,12].

A study in Sweden examining medical and criminal records [13] investigated the link between bipolar disorder and violent crime. Compared to the general population, individuals with bipolar disorder had an adjusted odds ratio (AOR) of 2.3 for violent crimes (95% CI = 2.0–2.6). The risk was significantly higher among those with comorbid substance use disorders, with an AOR of 6.4 (95% CI = 5.1–8.1). Conversely, individuals with bipolar and related disorders without comorbid substance use had a significantly lower AOR of 1.3 (95% CI = 1.0–1.5). Notably, within the broader category of bipolar and related disorders—including mania, depression, and psychotic features—there were no significant differences in violent crime risk among these subgroups. However, variations in how violent crime was defined and differences in research methodologies across studies should be considered when interpreting these findings.

The global prevalence of substance use disorders is approximately 2.2% [14], encompassing alcohol, stimulants, sedatives, hypnotics, cannabis, opioids, and hallucinogens. Individuals who use these substances have a 4- to 10-fold higher risk of committing violent crimes than non-users [15], a risk influenced by the complex neurophysiological changes induced by substance use [16]. For instance, both long-term alcohol consumption [17] and short-term binge drinking [18] can disrupt serotonin balance and overstimulate dopamine, leading to heightened mental activity, increased sensory-seeking behavior, provocation, and impulsivity [19,20]. Stimulants, meanwhile, enhance dopamine, serotonin, and norepinephrine release in the central nervous system, resulting in euphoria, heightened sensory perception, increased libido, anxiety, confusion, agitation, hallucinations, and delusions. In severe cases, these effects can contribute to violent behavior or suicidal tendencies [21,22]. However, substance users may also engage in criminal activity for reasons beyond neurophysiological effects, such as financial motives to sustain substance use [23].

Recent large-scale research on this topic in East Asia includes a study by Kim et al. that analyzed judicial databases [24]. Their findings suggest that individuals with severe mental illness have a higher likelihood of committing homicide, arson, and substance-related offenses than the general population. However, previous studies on individuals with mental illness reintegrated into society after hospital discharge suggest that when symptoms are stable, their risk of posing a threat is comparable to that of the general population. Conversely, individuals with substance use disorders present a significantly higher risk [25]. Overall, the relationship between substance use disorders, severe mental illness (such as schizophrenia and bipolar disorder) [26], and violent crime is unlikely to be a simple additive effect. Furthermore, variations in offense classification and sample sources may significantly influence analytical outcomes.

Data on offenders with mental illness can be sourced from medical records, social welfare systems, the criminal justice system, and forensic psychiatric evaluations. These evaluations are typically conducted by psychiatric experts, psychologists, and social workers who compile comprehensive reports. By integrating both dynamic and static risk factors associated with criminal behavior, these reports serve as valuable tools for analysis and practical application. We believe that through these data, we can identify variables potentially relevant to the relationship between mental illness, substance use, and criminal behavior. These variables warrant further investigation and may provide an opportunity to develop an integrated theoretical framework in this field.

Forensic psychiatric evaluations have been instrumental in analyzing crime patterns and identifying risk factors across different regions. In Sweden, forensic psychiatrists have used these reports to analyze crime patterns among individuals with intellectual disabilities [27]. In Lithuania, experts have examined them to identify potential risk factors for homicides committed under the influence of alcohol [28]. Similarly, researchers in Egypt have extracted variables from forensic psychiatric reports in both criminal and civil cases to assess potential criminogenic factors among offenders [29]. These studies highlight the value of forensic psychiatric evaluations in providing deeper insights into offenders’ medical conditions, treatment needs, correctional strategies, and preventive measures, both before and after trial.

Building on this framework, we aimed to analyze offenders documented in forensic psychiatric evaluation reports to test the following hypotheses: (1) Severe mental illness, including schizophrenia and bipolar disorder, as well as substance-related and addictive disorders, are each associated with violent crime. (2) Gender, treatment adherence, history of violent crime, and comorbid substance-related and addictive disorders influence the relationship between severe mental illness and violent crime.

2. Materials and methods

2.1. Case demographic information

This retrospective study was conducted at a psychiatric specialty hospital in northern Taiwan, where the population density is approximately 1,800 people per square kilometer and the crime rate is approximately 1,000 per 100,000 people [30]. The forensic psychiatry evaluation team of the hospital conducts forensic psychiatric evaluations for criminal cases referred by prosecutors or judges. These evaluations determine psychiatric diagnoses, criminal responsibility, trial competence, and other forensic considerations, culminating in formal forensic reports. Offenders are typically referred for forensic psychiatric evaluation several months after committing a crime, often having already received psychiatric treatment elsewhere. This study reviewed forensic psychiatric evaluation reports completed at the hospital between October 2009 and February 2022. Civil cases and victim assessments were excluded, yielding a final sample of 648 cases. Diagnoses were based on criteria from either the DSM-IV-TR [31] or the DSM-5 [32]. The evaluation process involved a multidisciplinary team comprising two psychiatrists, one psychologist, and one social worker, all of whom conducted interviews. This study was approved by the ethics committee of the hospital (IRB approval number: B20210722-2). We had no direct contact with the individuals evaluated, and the study did not interfere with their evaluations, treatment, or management. The research team accessed the forensic psychiatric evaluation data on April 24, 2022, for analysis purposes.

2.2. Classification of violent crime

The primary dependent variable in this study was violent crime, defined as offenses, including homicide, attempted homicide, aggravated assault, battery, arson, domestic violence, sexual offenses, robbery, intimidation, and unlawful detention [33,34]. Offenders were categorized as “violent” or “non-violent” based on the charges they faced at prosecution, aligning with the established definition of violent crime.

2.3. Sociodemographic factors

In this study, we examined key demographic variables, including age, gender, education level, employment status, and marital status. Education level is categorized based on whether an individual completed a compulsory junior high school education. Employment status is classified according to whether an individual was engaged in paid work at the time of the offense. Marital status is divided into three categories—single, married, or separated.

2.4. Clinical factors

The clinical factors included in this study are family history of mental illness, substance exposure history, suicide history, prior psychiatric evaluations, and treatment adherence. A family history of mental illness is defined as having a first-, second-, or third-degree relative diagnosed with a mental illness, as documented in the forensic evaluation report. This includes schizophrenia spectrum and other psychotic disorders, bipolar and related disorders, depressive disorders, substance-related and addictive disorders, and intellectual disabilities. Suicide history refers to documented suicide attempts involving actual self-harm, excluding suicidal ideation. The absence of prior psychiatric evaluation is defined as having never undergone a psychiatric evaluation before the offense based on forensic evaluation records. Poor treatment adherence is classified as following prescribed pharmacological or non-pharmacological treatment at a rate of less than 80% in terms of the number of sessions attended, frequency, or timing, as recorded in medical reports [35].

2.5. Forensic factors

Forensic factors assessed in this study include a history of violent crime and diagnoses from forensic psychiatric evaluations. A history of violent crime is defined as any previously documented offenses in forensic psychiatric evaluation reports, including homicide, attempted homicide, aggravated assault, sexual offenses, robbery, intimidation, unlawful detention, battery, arson, and domestic violence. Diagnoses from forensic psychiatric evaluations are classified according to the diagnoses recorded in these reports. The primary diagnostic categories include schizophrenia spectrum and other psychotic disorders, bipolar and related disorders, depressive disorders, substance-related and addictive disorders, neurocognitive disorders, personality disorders, and intellectual disabilities. For analytical purposes, schizophrenia spectrum and other psychotic disorders, along with bipolar and related disorders, are grouped under the severe mental illness category [26].

2.6. Static and dynamic factors of violent crime

Our study defines static and dynamic factors of violent crime based on demographic, clinical, and forensic evaluation data from forensic psychiatric evaluation reports, as well as meta-analyses of recidivism risk factors among offenders with mental illnesses [8]. Static factors include age, male gender, incomplete compulsory education, a family history of severe mental illness, a prior history of violent crime, and the absence of prior psychiatric evaluation before the offense. Dynamic factors include unemployment, single marital status, severe mental illness, substance-related and addictive disorders, and poor treatment adherence.

2.7. Statistical analyses

This study includes both continuous and categorical variables across demographic, clinical, and forensic evaluation-related factors. Continuous variables were reported as means and standard deviations, while categorical variables were expressed as frequencies and percentages. Bivariate analyses were conducted using independent sample t-tests for continuous variables and chi-square tests for categorical variables. Multiple logistic regression was performed to examine associations between static and dynamic crime factors (independent variables) and offender classification (violent vs. non-violent) as the dependent variable. Independent variables were entered into the statistical model using the Enter method. Model fit in logistic regression analysis were assessed using the Hosmer–Lemeshow goodness-of-fit test. Statistical significance was set at p < 0.05, with all tests conducted as two-tailed analyses.

To assess whether the static factors—male gender and history of violent crime—and the dynamic factors—poor treatment adherence and diagnoses from forensic psychiatric evaluation of substance-related and addictive disorders—moderate the relationship between severe mental illness and violent crime, a moderation analysis was conducted using Hayes’ PROCESS macro in SPSS [36]. Each factor was examined individually, with other factors included as covariates to control for potential confounding effects. Multicollinearity diagnostics indicated acceptable levels across all predictors, with variance inflation factors (VIFs) below 2.0, suggesting that multicollinearity was not a concern in the regression models.

In addition, to minimize the potential influence of crime classification on the study results, we conducted the same set of comparisons and analyses using the most violent and the most common non-violent crime categories. Specifically, we compared homicide and theft offenders in terms of sociodemographic, clinical, and forensic factors, followed by regression analyses of static and dynamic factors, and finally, moderation analyses. This approach was intended to determine whether crime classification had a substantial impact on the study findings.

3. Results

3.1. Sociodemographic factors

The sample had a mean age of 39.20 ± 11.98 years, with 79.0% male, 18.7% not completing compulsory education, 90.1% unemployed, and 90.9% single. Table 1 presents the differences in the demographic factors of violent and non-violent offenders. Violent offenders were significantly more likely to be male (89.8% vs. 69.5%, p < 0.001), slightly less likely to be unemployed (87.5% vs. 92.4%, p = 0.047), and had a lower proportion of single status (87.2% vs. 94.2%, p = 0.002). Additionally, a higher proportion of violent offenders were married compared to non-violent offenders (12.2% vs. 5.5%, p = 0.003).

Table 1. Comparison of sociodemographic factors between violent and non-violent offenders.

Violent offenders (n = 304) Non-violent offenders

(n = 344)
Mean SD Mean SD t p value
Age 38.62 12.11 39.72 11.85 −1.170 0.243
n % n % χ2 p value
Male gender 273 89.8 239 69.5 40.207 <0.001
Incomplete national

education
60 19.7 61 17.7 0.427 0.545
Unemployed 266 87.5 318 92.4 4.428 0.047
Marital status
Single 265 87.2 324 94.2 9.596 0.002
Separated 2 0.7 1 0.3 0.472 0.603
Married 37 12.2 19 5.5 9.033 0.003

3.2. Clinical factors

In the total sample, 13.6% had a family history of severe mental illness, while 17.3% had never undergone psychiatric evaluation before committing the crime. Moreover, 92.4% exhibited poor treatment adherence. Table 2 presents the clinical differences between violent and non-violent offenders. Violent offenders were significantly more likely to have no prior psychiatric evaluation before the offense than non-violent offenders (24.7% vs. 10.8%, p < 0.001).

Table 2. Comparison of clinical factors between violent and non-violent offenders.

Violent offenders (n = 304) Non-violent offenders

(n = 344)
χ2 p value
n % n %
Family history
 Severe mental illness 38 12.5 50 14.5 0.569 0.491
 Schizophrenia spectrum and

other psychotic disorders
31 10.2 41 11.9 0.484 0.532
 Bipolar and other related

disorder
8 2.6 10 2.9 0.045 1.000
 Depressive disorder 21 6.9 41 11.6 4.216 0.044
 Substance-related and addictive

disorders
37 12.2 52 15.1 1.182 0.304
 Intellectual disability 14 4.6 16 4.7 0.001 1.000
 Suicide history 35 11.5 34 9.9 0.450 0.525
 No prior psychiatric evaluation 75 24.7 37 10.8 21.858 <0.001
 Poor treatment adherence 277 91.1 322 93.6 1.427 0.238

3.3. Forensic factors

In the total sample, homicide cases constituted 5.4%, attempted homicide 6.8%, and sexual offenses constituted 14.5%. Non-violent crimes accounted for 62.7% of the cases, with theft representing 30.6%. Among individuals who underwent forensic psychiatric evaluations, 44.9% were diagnosed with severe mental illness, while 28.4% had substance-related and addictive disorders. Table 3 presents the differences in forensic psychiatric assessment-related factors between violent and non-violent offenders. Compared to non-violent offenders, violent offenders had a significantly higher prevalence of a history of violent crime (28.6% vs. 19.2%, p = 0.005).

Table 3. Comparison of forensic factors between violent and non-violent offenders.

Violent offenders (n = 304) Non-violent offenders

(n = 344)


χ2


p value
n % n %
History of violent crimes 87 28.6 66 19.2 7.961 0.005
Forensic diagnosis
 Severe mental illness 129 42.4 162 47.1 1.416 0.237
 Schizophrenia spectrum and other psychotic disorders 116 38.2 141 41.0 0.540 0.470
 Bipolar and other related

disorder
13 4.3 21 6.1 1.085 0.378
 Depressive disorder 30 9.9 42 12.2 0.895 0.382
 Substance-related and addictive

disorders
92 30.3 92 26.7 0.983 0.338
 Neurocognitive disorders 18 5.9 29 8.4 1.510 0.229
 Intellectual disability 38 12.5 52 15.1 0.924 0.364
 Personality disorders 9 3.0 4 1.2 2.653 0.159

3.4. Analysis of static and dynamic violent crime factors

Table 4 presents the associations between static and dynamic crime factors and violent offenders. Male (OR: 3.87; 95% CI: 2.42–6.19), absence of prior psychiatric evaluation before the offense (OR: 2.38; 95% CI: 1.50–3.78), and a history of violent crime (OR: 1.73; 95% CI: 1.10–2.72) were significantly associated with an increased likelihood of being a violent offender. Conversely, being single (OR: 0.34; 95% CI: 0.18–0.64) was associated with a reduced likelihood of being a violent offender. The model showed a good fit (Hosmer–Lemeshow statistics = 6.137, p = 0.632).

Table 4. The associations between static and dynamic crime factors and violent offenders.

Violent offenders
OR 95% CI
Static factors
 Age 0.99 0.98–1.01
 Male gender 3.87 2.42–6.19
 Incomplete national education 1.19 0.76–1.87
 Family history of severe mental illness 0.90 0.56–1.48
 No prior psychiatric evaluation 2.38 1.50–3.78
 History of violent crimes 1.73 1.10–2.72
Dynamic factors
 Unemployed status 0.75 0.43–1.32
 Single status 0.34 0.18–0.64
 Severe mental illness 1.11 0.78–1.59
 Substance-related and addictive disorders 1.08 0.74–1.57
 Poor treatment adherence 0.79 0.42–1.47
 Hosmer–Lemeshow goodness-of-fit test p value = 0.632
 OR, odds ratio; CI, confidence interval

3.5. Moderation analysis

Table 5 summarizes the results of the moderation analysis. Gender, treatment adherence, history of violent crime, and substance-related and addictive disorders did not significantly moderate the association between severe mental illness and violent crime.

Table 5. Moderation analysis.

Coefficient SE Z p value 95% CI
Gender on the association between severe mental illness and violent crime
 Severe mental illness −0.60 0.57 −1.05 0.29 −1.71–0.51
 Gender 1.32 0.39 3.41 <0.01 0.56–2.09
 Gender × Severe mental illness 0.51 0.60 0.85 0.40 −0.67–1.69
Treatment adherence on the association between severe mental illness and violent crime
 Severe mental illness −0.11 0.63 −0.17 0.86 −1.35–1.13
 Treatment adherence −0.14 0.50 −0.28 0.78 −1.12–0.84
 Treatment adherence × Severe mental illness −0.40 0.66 −0.06 0.95 −1.34–1.26
History of violent crime on the association between severe mental illness and violent crime
 Severe mental illness −0.14 0.21 −0.66 0.51 −0.56–0.28
 History of violent crime 0.24 0.32 0.74 0.46 −0.39–0.86
 History of violent crime × Severe mental illness −0.41 0.49 −0.08 0.93 −1.00–0.92
Substance-related and addictive disorders on the association between severe mental illness and violent crime
 Severe mental illness −0.04 0.22 −0.19 0.85 −0.47–0.39
 Substance-related and addictive disorders −0.38 0.25 −1.52 0.13 −0.87–0.11
 Substance-related and addictive disorders × Severe mental illness −0.53 0.50 −1.06 0.29 −1.52–0.45

SE, standard error; CI, confidence interval

3.6. Sensitivity analysis

As part of the sensitivity analysis, we examined whether crime classification influenced the study results by conducting the same set of comparisons and analyses using the most violent and the most common non-violent crime categories—homicide and theft. Sociodemographic, clinical, and forensic factors were compared between homicide and theft offenders, followed by regression analyses of static and dynamic factors and moderation analyses. As shown in Table S4 in S1 File, being male (OR: 3.44; 95% CI: 1.04–11.38) and having never undergone psychiatric evaluation prior to the offense (OR: 3.19; 95% CI: 1.03–9.89) were associated with a higher likelihood of being a homicide offender.

As presented in Table S5 in S1 File, none of the moderation effects were statistically significant, including gender, treatment adherence, history of violent crime, and substance-related and addictive disorders in moderating the association between severe mental illness and homicide offending.

4. Discussion

In this study, we examined the association between severe mental illness, substance-related and addictive disorders, and violent crime in a sample of 648 offenders referred for forensic psychiatric evaluation by prosecutors or judges. Additionally, we investigated whether gender, treatment adherence, history of violent crime, and comorbid substance-related and addictive disorders moderated this association. The findings did not support the research hypotheses. Among the static factors, male gender, absence of prior psychiatric evaluation before the offense, and a history of violent crime were the strongest predictors of violent crime. Conversely, being single—a dynamic factor—was more closely associated with non-violent crime.

In the preceding section, we reviewed large-scale database studies from Western countries [9,13], which have suggested that individuals with serious mental illness may be at higher risk of involvement in violent crime compared to the general population. However, our study did not use a general population comparison group. Instead, we focused on differentiating violent and non-violent offenders within a forensic sample. Our analysis revealed that serious mental illness was not significantly associated with violent offending in this offender population. This finding suggests that, among individuals who have already committed crimes, other risk factors beyond serious mental illness may play a more prominent role in distinguishing violent offenders from non-violent ones.

The average age, gender distribution, and crime type proportions in this study sample closely align with national crime statistics [34]. Among diagnoses from forensic psychiatric evaluations, schizophrenia spectrum and other psychotic disorders were the most prevalent (39.7%), followed by substance-related and addictive disorders (28.4%), intellectual disability (13.9%), and depression (11.1%). Epidemiological data indicate that schizophrenia affects approximately 0.33–0.75% of the global population [37,38], with a domestic prevalence of approximately 0.44% [39]. The global prevalence of substance-related and addictive disorders is estimated at 2.2% [14], while alcohol use disorders affect approximately 3% of the domestic population [40]. Psychotic disorders induced by other substances are estimated to affect at least 0.02–0.03% of individuals [39]. Additionally, intellectual disability affects approximately 0.4% of the domestic population [41], while depression affects approximately 1.2% of the population [42]. The stark contrast between these general prevalence rates and the diagnostic distribution in this study underscores the distinct psychiatric profile of the forensic population examined.

It is essential to note that the sample in this study consisted of offenders referred for forensic psychiatric evaluation by judicial authorities, meaning that all individuals were diagnosed with a mental disorder following evaluation. A significant proportion (49%) had severe mental illness, with schizophrenia spectrum and other psychotic disorders being the most prevalent (39.7%). Among both violent and non-violent offenders, schizophrenia spectrum and other psychotic disorders remained the most common diagnoses, each exceeding 30%. However, regression analysis revealed no significant association between severe mental illness and violent crime. Similarly, other psychiatric diagnoses, including depression and substance-related and addictive disorders, showed no significant association with violent crime—contrasting with findings from previous research. This discrepancy suggests that while mental illness may differentiate offenders from the general population, it may not reliably distinguish violent from non-violent offenders within the offender group.

In this study, 28.4% of offenders were diagnosed with substance-related and addictive disorders—a prevalence notably higher than in general epidemiological samples. This disparity likely reflects the distinct characteristics of the offender population examined.

Furthermore, only 2% of the sample underwent a forensic psychiatric diagnosis of personality disorder, a rate lower than the global prevalence of 7.8% [43] but higher than the domestic epidemiological estimate of 0.02% [39]. This discrepancy raises questions about whether personality disorders are underdiagnosed in forensic psychiatric evaluations of offenders within the domestic judicial system or if domestic diagnostic criteria are more conservative than those used internationally. Further research is needed to explore this issue.

The populations studied, including individuals with severe mental illness and substance use disorders, are epidemiologically more prevalent among males. Similarly, offender populations, particularly violent offenders, are predominantly male, as widely documented.

Biological research on violent crime among Chinese males suggests that variations in serotonin receptor polymorphisms may contribute to the higher proportion of male offenders [44,45]. From a neurodevelopmental and animal model perspective, the relationship between violent crime and neurotransmitters, such as dopamine and serotonin [46] may be influenced by maternal smoking during pregnancy [47]. Additionally, elevated testosterone levels have been proposed as a factor in male violent offenders [48]. Brain imaging studies further indicate that male violent offenders exhibit reduced gray matter volume in the insula compared to their non-violent counterparts [49], which may impair impulse control and emotional regulation. However, gender-based crime studies must account for potential biases. Higher arrest rates and harsher sentencing for male offenders than females could influence the study samples [50]. Understanding violent crime through a gendered lens may also benefit from sociological frameworks, such as differential association and social control theories, which examine the role of socialization and external influences on offender behavior. These perspectives provide a broader understanding beyond biological determinism, avoiding an oversimplified causal link between sex and violent crime [51].

Of the 648 individuals in this study, 112 had never undergone a psychiatric evaluation before the crimes. Over 50% had no history of violent crime. Following forensic psychiatric evaluation, 23 (20%) were diagnosed with severe mental illness, while 37 (30%) had substance-related and addictive disorders. Among these, 24 (64.9%) had alcohol use disorders, and 15 (40.5%) had stimulant use disorders. The remaining 52 (46.4%) were diagnosed with depression, neurocognitive disorders, intellectual disabilities, or other less common psychiatric conditions. These findings indicate that individuals classified as having “never received psychiatric evaluation before committing a crime” represent a highly heterogeneous group, with diagnoses extending beyond severe mental illness and substance-related and addictive disorders. This raises a critical question: Could the actual risk posed by individuals with untreated psychiatric conditions be systematically underestimated?

Regression analysis revealed a significant association between a history of violent crime and violent crime, whereas severe mental illness showed no such link. Similarly, moderation analysis revealed that gender, treatment adherence, history of violent crime, and substance-related and addictive disorders did not moderate the association between severe mental illness and violent crime. These findings indicate that offenders referred for forensic psychiatric evaluation due to violent crime are not necessarily those with severe mental illness.

Single status and unemployment are often cited as risk factors for criminal behavior. However, this study found no significant association between either factor and violent crime. Instead, single status was more closely associated with non-violent offenses. A large-scale Finnish study [52] similarly reported higher overall crime rates among single individuals, but the association between marital status and violent crime became insignificant when analyzed separately. These findings indicate that single status and unemployment may not directly increase the risk of crime but instead reflect underlying issues, such as inadequate social support or economic hardship. Further research is needed to clarify these relationships.

It is noteworthy that this study did not take into account the victims and situational factors involved in these cases. In future research, if such data can be adequately collected and incorporated into the analysis, it may allow for a more comprehensive exploration of how these factors influence the relationship between diagnosis and criminal behavior. In addition, we must also recognize the diversity of diagnoses, the blind spots in diagnostic descriptions, and the need to incorporate into future research the longitudinal dimension of symptom severity and impact within the diagnostic framework.

This study has several limitations. First, the classification and analysis of variables relied on forensic psychiatric evaluation reports, which limited the ability to comprehensively assess offenders’ living environments, early life experiences, and objective measures of symptom severity. Second, inconsistencies in report quality were unavoidable. While some provided a detailed crime context, others differed in their descriptions of the relationship between circumstances and criminal behavior due to variations in evaluation objectives or focal points. Consequently, situational factors could not be quantitatively analyzed. Third, only 2% of the reports referenced a personality disorder diagnosis, and the terminology used for personality assessments varied, making it challenging to include personality traits and temperament as adjustment variables. Fourth, the sample primarily consisted of individuals referred by prosecutors for forensic psychiatric evaluation within a specific region, and most of the evaluations were conducted by a single institution. In the region where this study was conducted, Taiwan, negative stigmas toward mental illness still persist. Currently, there is no scientifically established standard for referring individuals for forensic psychiatric evaluation. Such referrals are typically made by prosecutors, and during the study period, defendants were not even legally guaranteed the right to request a psychiatric evaluation. Therefore, the representativeness of the sample is limited, and the generalizability of the findings should be interpreted with caution.

Finally, since the study sample consisted solely of offenders referred for forensic psychiatric evaluation, our findings have limited generalizability and cannot be directly compared to the prevalence or comorbidity patterns of mental disorders in the general population or among offenders who were not evaluated.

5. Conclusion

In this study, we examined offenders referred for forensic psychiatric evaluation and found that violent offenders who underwent such evaluations do not necessarily have severe mental illness or substance-related and addictive disorders. Moreover, factors such as male gender, poor treatment adherence, a history of violent crime, and comorbid addiction are insufficient to explain the relationship between severe mental illness and violent crime. It is crucial to avoid directly equating violent offenders with severe mental illness. Meanwhile, further research is needed to identify the factors that contribute to the involvement of individuals with severe mental illness in the criminal justice system. Efforts should also ensure they receive proper treatment and the necessary support for successful reintegration into society.

Supporting information

S1 File. Supplementary Tables.

(DOCX)

pone.0336918.s001.docx (26.4KB, docx)
S2 Checklist. Inclusivity in global research questionnaire.

(DOCX)

pone.0336918.s002.docx (65.1KB, docx)
S3 Data. Original dataset used for analyses.

(XLSX)

pone.0336918.s003.xlsx (329.2KB, xlsx)

Data Availability

All relevant data are available within the paper and its Supporting Information files. We have also uploaded the de-identified data onto the site The Qualitative Data Repository https://qdr.syr.edu/ The DOI is https://doi.org/10.5064/F6JZOYI6. Please also refer to the site https://data.qdr.syr.edu/dataset.xhtml?persistentId=doi%3A10.5064/F6JZOYI6.

Funding Statement

The author(s) received no specific funding for this work.

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Decision Letter 0

Vincenzo De Luca

17 Jul 2025

Factors associated with violent offenders with mental illness in forensic psychiatric evaluations

PLOS ONE

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[Note: HTML markup is below. Please do not edit.]

Reviewers' comments:

Reviewer's Responses to Questions

Comments to the Author

1. Is the manuscript technically sound, and do the data support the conclusions?

Reviewer #1: Yes

**********

2. Has the statistical analysis been performed appropriately and rigorously? -->?>

Reviewer #1: Yes

**********

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The PLOS Data policy

Reviewer #1: No

**********

4. Is the manuscript presented in an intelligible fashion and written in standard English??>

Reviewer #1: Yes

**********

Reviewer #1: This retrospective study of Chinese forensic evaluation reports, N=648, tested the hypotheses: “(1) Severe mental illness, including schizophrenia and bipolar disorder, as well as substance-related and addictive disorders, are each associated with violent crime. (2) Gender, treatment adherence, history of violent crime, and comorbid substance-related and addictive disorders influence the relationship between severe mental illness and violent crime.”

They examined key demographic variables, including age, gender, education level, employment status, and marital status, plus clinical factors such as family history of mental illness, substance exposure history, suicide history, prior psychiatric evaluations, treatment adherence, and suicide history.

“Primary diagnostic categories found in the study included schizophrenia spectrum and other psychotic disorders, bipolar and related disorders, depressive disorders, substance-related and addictive disorders, neurocognitive disorders, personality disorders, and intellectual disabilities. For analytical purposes, schizophrenia spectrum and other psychotic disorders, along with bipolar and related disorders, are grouped under the severe mental illness category”.

“Bivariate analyses will be conducted using independent sample t-tests for continuous variables and chi-square tests for categorical variables. Multiple logistic regression will be performed to examine associations between static and dynamic crime factors (independent variables) and offender classification (violent vs. nonviolent) as the dependent variable.”

All of the above statistical design and results appear to be appropriate, but I was confused as to why all of the description in the Methods was written in future tense instead of past tense. Their conclusion is “These findings indicate that offenders referred for forensic psychiatric evaluation due to violent crime are not necessarily those with severe mental illness”.

Although they have some interesting neurochemical speculation on the reason for violent crime in their sample, I did not see an adequate rebuttal to the papers in their literature that DID find an association of major mental illness with violent crime.

Apart from that, their methods and conclusions appear to have been well-done.

**********

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Reviewer #1: No

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PLoS One. 2025 Dec 17;20(12):e0336918. doi: 10.1371/journal.pone.0336918.r002

Author response to Decision Letter 1


5 Aug 2025

Dear Editors,

Thank you very much for your time and the opportunity to revise our manuscript entitled “Factors associated with violent offenders with mental illness in forensic psychiatric evaluations.” We greatly appreciate the constructive comments and suggestions provided by you and the reviewers, which have been very helpful in improving the quality of our manuscript.

We have carefully revised the manuscript in accordance with the reviewer’s comments. Below, we provide detailed responses to each point raised.

________________________________________

Additional Requirement:

1.Please ensure that your manuscript meets PLOS ONE's style requirements, including those for file naming. The PLOS ONE style templates can be found at

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Response: Thank you for the reminding. We have checked the format of out manuscript.

2. Please include a complete copy of PLOS’ questionnaire on inclusivity in global research in your revised manuscript. Our policy for research in this area aims to improve transparency in the reporting of research performed outside of researchers’ own country or community. The policy applies to researchers who have travelled to a different country to conduct research, research with Indigenous populations or their lands, and research on cultural artefacts. The questionnaire can also be requested at the journal’s discretion for any other submissions, even if these conditions are not met. Please find more information on the policy and a link to download a blank copy of the questionnaire here: https://journals.plos.org/plosone/s/best-practices-in-research-reporting. Please upload a completed version of your questionnaire as Supporting Information when you resubmit your manuscript.

Response: We have completed the questionnaire and attached the information over the end part of the manuscript.

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“nil”

Please complete your Competing Interests on the online submission form to state any Competing Interests. If you have no competing interests, please state "The authors have declared that no competing interests exist.", as detailed online in our guide for authors at http://journals.plos.org/plosone/s/submit-now

This information should be included in your cover letter; we will change the online submission form on your behalf.

Response: Sure. Thanks.

4. We note that you have indicated that there are restrictions to data sharing for this study. PLOS only allows data to be available upon request if there are legal or ethical restrictions on sharing data publicly. For more information on unacceptable data access restrictions, please see http://journals.plos.org/plosone/s/data-availability#loc-unacceptable-data-access-restrictions.

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Response: Sure. We had uploaded the de-identified data onto the site The Qualitative Data Repository https://qdr.syr.edu/ The DOI is https://doi.org/10.5064/F6JZOYI6. Please also refer to the site https://data.qdr.syr.edu/dataset.xhtml?persistentId=doi%3A10.5064/F6JZOYI6

5. Please include your tables as part of your main manuscript and remove the individual files. Please note that supplementary tables (should remain/ be uploaded) as separate "supporting information" files

Response: Sure. We have included the tables into our manuscript.

6. If the reviewer comments include a recommendation to cite specific previously published works, please review and evaluate these publications to determine whether they are relevant and should be cited. There is no requirement to cite these works unless the editor has indicated otherwise.

Response: The reviewer did not mention some citations of published works.

Reviewer #1

1. All of the above statistical design and results appear to be appropriate, but I was confused as to why all of the description in the Methods was written in future tense instead of past tense.

Response: Thank you for the reminding. We have changed the future-tense descriptions in the method section to past-tense uses. Kindly refer to lines 220-234 on page 11.

“This study includes both continuous and categorical variables across demographic, clinical, and forensic evaluation-related factors. Continuous variables were reported as means and standard deviations, while categorical variables were expressed as frequencies and percentages. Bivariate analyses were conducted using independent sample t-tests for continuous variables and chi-square tests for categorical variables. Multiple logistic regression was performed to examine associations between static and dynamic crime factors (independent variables) and offender classification (violent vs. non-violent) as the dependent variable. Independent variables were entered into the statistical model using the Enter method. Model fit in logistic regression analysis were assessed using the Hosmer–Lemeshow goodness-of-fit test. Statistical significance was set at p < 0.05, with all tests conducted as two-tailed analyses.

To assess whether the static factors—male gender and history of violent crime—and the dynamic factors—poor treatment adherence and diagnoses from forensic psychiatric evaluation of substance-related and addictive disorders—moderate the relationship between severe mental illness and violent crime, a moderation analysis was conducted using Hayes’ PROCESS macro in SPSS [36]. Each factor was examined individually, with other factors included as covariates to control for potential confounding effects.”

2. Their conclusion is “These findings indicate that offenders referred for forensic psychiatric evaluation due to violent crime are not necessarily those with severe mental illness.” Although they have some interesting neurochemical speculation on the reason for violent crime in their sample, I did not see an adequate rebuttal to the papers in their literature that DID find an association of major mental illness with violent crime.

Response: Thank you for your kind reminder. To enhance the alignment with the reviewed literature, we have revised the relevant descriptions in the Discussion section. Kindly refer to lines 295-302 on page 17.

“In the preceding section, we reviewed large-scale database studies from Western countries [9,13], which have suggested that individuals with serious mental illness may be at higher risk of involvement in violent crime compared to the general population. However, our study did not use a general population comparison group. Instead, we focused on differentiating violent and non-violent offenders within a forensic sample. Our analysis revealed that serious mental illness was not significantly associated with violent offending in this offender population. This finding suggests that, among individuals who have already committed crimes, other risk factors beyond serious mental illness may play a more prominent role in distinguishing violent offenders from non-violent ones.”

Attachment

Submitted filename: Rebuttal letter 20250720.docx

pone.0336918.s005.docx (22.4KB, docx)

Decision Letter 1

Vincenzo De Luca

12 Oct 2025

Dear Dr. Chan,

Thank you for submitting your manuscript to PLOS ONE. After careful consideration, we feel that it has merit but does not fully meet PLOS ONE’s publication criteria as it currently stands. Therefore, we invite you to submit a revised version of the manuscript that addresses the points raised during the review process.

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Vincenzo De Luca

Academic Editor

PLOS ONE

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Reviewers' comments:

Reviewer's Responses to Questions

Comments to the Author

Reviewer #1: All comments have been addressed

Reviewer #2: All comments have been addressed

Reviewer #3: (No Response)

**********

2. Is the manuscript technically sound, and do the data support the conclusions??>

Reviewer #1: Yes

Reviewer #2: Yes

Reviewer #3: Yes

**********

3. Has the statistical analysis been performed appropriately and rigorously? -->?>

Reviewer #1: (No Response)

Reviewer #2: Yes

Reviewer #3: Yes

**********

4. Have the authors made all data underlying the findings in their manuscript fully available??>

The PLOS Data policy

Reviewer #1: Yes

Reviewer #2: (No Response)

Reviewer #3: (No Response)

**********

5. Is the manuscript presented in an intelligible fashion and written in standard English??>

Reviewer #1: Yes

Reviewer #2: Yes

Reviewer #3: Yes

**********

Reviewer #1: Thank you for your revised manuscript. It answers all my previous questions and as it turns out, I do not have any further queries for you.

Reviewer #2: An interesting and easy to read paper that adds on to the literature on SUDs and concurrent disorders in an important way. Very minor writing edits needed (e.g., had a lower proportion of single "status" in line 242). Please describe the statement, "Compared to non-violent offenders, violent offenders had a significantly higher prevalence of a history of violent crime (28.6% vs. 19.2%, p = 0.005)" in line 263 and why the 19.2% of non-violent offenders with a history of violent crime would not be considered as violent offenders. Please also add on a big limitation of the sample being derived from a single site. May be fruitful to add in the Discussion the possibility of a combination of different factors over defined moderators that relates to violent crime.

Reviewer #3: This study addresses an important and sensitive topic—the association between severe mental illness and violent crime—using a large sample of forensic psychiatric evaluations in Taiwan. The work contributes valuable data from a non-Western context, but the paper would benefit from deeper theoretical integration and a clearer justification of analytic choices and interpretations.

Major Comments

– The Introduction would benefit from a clearer theoretical model linking mental illness, substance use, and violence. The current framing is largely descriptive and does not sufficiently articulate how this study advances existing literature or addresses prior inconsistencies.

– The manuscript states that all participants were referred for forensic evaluation, which introduces a selection bias. This limitation should be more explicitly acknowledged and discussed in relation to the generalizability of findings.

– Although based on established sources, the broad inclusion of offenses (e.g., intimidation, unlawful detention) may dilute distinctions between severe and moderate violence. The authors should justify this classification or provide sensitivity analyses using narrower definitions.

– The regression and moderation analyses appear correctly applied, but the rationale for including certain covariates is not always clear. It would strengthen the paper to clarify variable selection criteria and to report multicollinearity diagnostics.

– The conclusion that severe mental illness is not associated with violent crime within this sample is important, but the authors should avoid overgeneralizing this result. The Discussion could better explore alternative explanations, such as limited variance in psychiatric diagnoses or unmeasured mediating factors (e.g., symptom severity, treatment duration).

– Given that this study is based in Taiwan, the discussion could better highlight sociocultural aspects (e.g., mental health stigma, judicial referral patterns) that may influence both the prevalence of referrals and observed associations.

Minor Comments

- The tense in some sections (especially the Methods) has been corrected, but residual inconsistencies remain; please ensure uniform use of the past tense.

- The tables are informative but dense; consider summarizing key comparisons in the text rather than repeating all numerical results.

- Please verify reference formatting for PLOS ONE style (e.g., spacing and DOI presentation).

- Some typographical inconsistencies appear in the use of “addictive” vs. “additive” disorders.

- The Highlights section could be shortened to emphasize novel findings and clinical implications rather than restating results.

**********

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Reviewer #1: No

Reviewer #2: No

Reviewer #3: No

**********

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PLoS One. 2025 Dec 17;20(12):e0336918. doi: 10.1371/journal.pone.0336918.r004

Author response to Decision Letter 2


20 Oct 2025

Dear Editors,

We would like to express our sincere gratitude to the editorial team for their kind assistance and valuable guidance, which have greatly improved our manuscript. We hope that our responses this time will clearly convey our respect and appreciation to the reviewers. Our detailed replies are as follows.

Reviewer #2:

1. Very minor writing edits needed (e.g., had a lower proportion of single "status" in line 242).

Response: Thank you to the reviewer. We added the word status after single in line 261.

2. Please describe the statement, "Compared to non-violent offenders, violent offenders had a significantly higher prevalence of a history of violent crime (28.6% vs. 19.2%, p = 0.005)" in line 263 and why the 19.2% of non-violent offenders with a history of violent crime would not be considered as violent offenders.

Response: Thank you to the reviewer. To enhance clarity and avoid redundancy, we added a description in lines 186–187 of the Methods section, emphasizing that violent offenders were defined as individuals whose charges at the time of the forensic evaluation were categorized as violent crimes by the prosecutor.

3. Please also add on a big limitation of the sample being derived from a single site.

Response: Thank you to the reviewer. We added the following description in the Limitation section (lines 421–428):

“Fourth, the sample primarily consisted of individuals referred by prosecutors for forensic psychiatric evaluation within a specific region, and most of the evaluations were conducted by a single institution. In the region where this study was conducted, Taiwan, negative stigmas toward mental illness still persist. Currently, there is no scientifically established standard for referring individuals for forensic psychiatric evaluation. Such referrals are typically made by prosecutors, and during the study period, defendants were not even legally guaranteed the right to request a psychiatric evaluation. Therefore, the representativeness of the sample is limited, and the generalizability of the findings should be interpreted with caution.”

4. May be fruitful to add in the Discussion the possibility of a combination of different factors over defined moderators that relates to violent crime.

Response: Thank you to the reviewer. After considering this valuable suggestion, we added a new paragraph in lines 407–410:

“It is noteworthy that this study did not take into account the victims and situational factors involved in these cases. In future research, if such data can be adequately collected and incorporated into the analysis, it may allow for a more comprehensive exploration of how these factors influence the relationship between diagnosis and criminal behavior.”

Reviewer #3:

1. The Introduction would benefit from a clearer theoretical model linking mental illness, substance use, and violence. The current framing is largely descriptive and does not sufficiently articulate how this study advances existing literature or addresses prior inconsistencies.

Response: Thank you to the reviewer for this insightful comment. Currently, substance use is considered a potential interacting variable in the relationship between mental illness and violence, but existing studies vary in how much emphasis they place on this interaction. We believe that in our local context, where empirical research on this topic remains limited, it is still necessary to explore how to construct an integrated theoretical model. We added the following text in lines 145–148:

“We believe that through these data, we can identify variables potentially relevant to the relationship between mental illness, substance use, and criminal behavior. These variables warrant further investigation and may provide an opportunity to develop an integrated theoretical framework in this field.”

2. The manuscript states that all participants were referred for forensic evaluation, which introduces a selection bias. This limitation should be more explicitly acknowledged and discussed in relation to the generalizability of findings.

Response: Thank you to the reviewer. We added the following description in the Limitation section (lines 421–428):

“Fourth, the sample primarily consisted of individuals referred by prosecutors for forensic psychiatric evaluation within a specific region, and most of the evaluations were conducted by a single institution. In the region where this study was conducted, Taiwan, negative stigmas toward mental illness still persist. Currently, there is no scientifically established standard for referring individuals for forensic psychiatric evaluation. Such referrals are typically made by prosecutors, and during the study period, defendants were not even legally guaranteed the right to request a psychiatric evaluation. Therefore, the representativeness of the sample is limited, and the generalizability of the findings should be interpreted with caution.”

3. Although based on established sources, the broad inclusion of offenses (e.g., intimidation, unlawful detention) may dilute distinctions between severe and moderate violence. The authors should justify this classification or provide sensitivity analyses using narrower definitions.

Response: Thank you to the reviewer. To further clarify and distinguish this issue, we conducted an additional comparison between the most severe violent crime (homicide) and the most common non-violent crime (theft). We analyzed their sociodemographic, clinical, and forensic factors, as well as related interaction effects. These results were added to the Supplementary Materials. We also explained that this served as a sensitivity analysis to minimize the potential influence of crime classification on the findings. The results showed no substantial differences in the core associations. Please refer to lines 248–253:

“In addition, to minimize the potential influence of crime classification on the study results, we conducted the same set of comparisons and analyses using the most violent and the most common non-violent crime categories. Specifically, we compared homicide and theft offenders in terms of sociodemographic, clinical, and forensic factors, followed by regression analyses of static and dynamic factors, and finally, moderation analyses. This approach was intended to determine whether crime classification had a substantial impact on the study findings.”

And lines 305–315:

“As part of the sensitivity analysis, we examined whether crime classification influenced the study results by conducting the same set of comparisons and analyses using the most violent and the most common non-violent crime categories—homicide and theft. Sociodemographic, clinical, and forensic factors were compared between homicide and theft offenders, followed by regression analyses of static and dynamic factors and moderation analyses. As shown in Table S4, being male (OR: 3.44; 95% CI: 1.04–11.38) and having never undergone psychiatric evaluation prior to the offense (OR: 3.19; 95% CI: 1.03–9.89) were associated with a higher likelihood of being a homicide offender.

As presented in Table S5, none of the moderation effects were statistically significant, including gender, treatment adherence, history of violent crime, and substance-related and addictive disorders in moderating the association between severe mental illness and homicide offending.”

4. The regression and moderation analyses appear correctly applied, but the rationale for including certain covariates is not always clear. It would strengthen the paper to clarify variable selection criteria and to report multicollinearity diagnostics.

Response: Thank you to the reviewer. We cited relevant literature to support our inclusion of dynamic and static factors, ensuring that their selection was evidence-based. Additionally, we conducted a multicollinearity check using variance inflation factors (VIFs), which showed that all included variables had acceptable levels (VIF < 2.0), indicating no serious multicollinearity problems. We added the following description in lines 245–247:

“Multicollinearity diagnostics indicated acceptable levels across all predictors, with variance inflation factors (VIFs) below 2.0, suggesting that multicollinearity was not a concern in the regression models.”

5. The conclusion that severe mental illness is not associated with violent crime within this sample is important, but the authors should avoid overgeneralizing this result. The Discussion could better explore alternative explanations, such as limited variance in psychiatric diagnoses or unmeasured mediating factors (e.g., symptom severity, treatment duration).

Response: Thank you to the reviewer. We added the following discussion in lines 410-412:

“In addition, we must also recognize the diversity of diagnoses, the blind spots in diagnostic descriptions, and the need to incorporate into future research the longitudinal dimension of symptom severity and impact within the diagnostic framework.”

6. Given that this study is based in Taiwan, the discussion could better highlight sociocultural aspects (e.g., mental health stigma, judicial referral patterns) that may influence both the prevalence of referrals and observed associations.

Response: Thank you very much to the reviewer. We agree that these sociocultural factors influence the representativeness and generalizability of our findings. Therefore, we added the following description in the Limitation section (lines 423–428):

“In the region where this study was conducted, Taiwan, negative stigmas toward mental illness still persist. Currently, there is no scientifically established standard for referring individuals for forensic psychiatric evaluation. Such referrals are typically made by prosecutors, and during the study period, defendants were not even legally guaranteed the right to request a psychiatric evaluation.”

7. The tense in some sections (especially the Methods) has been corrected, but residual inconsistencies remain; please ensure uniform use of the past tense.

Response: Thank you to the reviewer. As we are not native English speakers, we had the manuscript reviewed by a native English editor. Upon discussion, we confirmed that variable definitions in the Methods section may appropriately use the present tense, while procedural descriptions should use the past tense. We carefully rechecked and corrected all remaining inconsistencies accordingly.

8. The tables are informative but dense; consider summarizing key comparisons in the text rather than repeating all numerical results.

Response: Thank you to the reviewer. We confirmed that the Results section now primarily highlights key comparative findings, with only a few representative descriptive statistics retained for context.

9. Please verify reference formatting for PLOS ONE style (e.g., spacing and DOI presentation).

Response: Thank you to the reviewer. We have rechecked, revised, and updated all references to comply with PLOS ONE formatting requirements.

10. Some typographical inconsistencies appear in the use of “addictive” vs. “additive” disorders.

Response: Thank you very much to the reviewer. We corrected all such typographical inconsistencies, primarily appearing in Tables 2–5.

11. The Highlights section could be shortened to emphasize novel findings and clinical implications rather than restating results.

Response: Thank you to the reviewer. We revised the Highlights as follows:

“�Stigmatization continues to hinder access to treatment, housing, and employment among individuals with mental illness.

�Violent offending cannot be attributed solely to severe mental illness; diverse diagnostic and psychosocial factors are involved.

�For offenders with mental illness, addressing clinical needs requires not only diagnostic evaluation but also integrated clinical and social interventions.

�Social isolation and unmet support needs represent critical targets for preventing reoffending and facilitating recovery.”

Decision Letter 2

Vincenzo De Luca

2 Nov 2025

<p>Factors associated with violent offenders with mental illness in forensic psychiatric evaluations

PONE-D-25-24024R2

Dear Dr. Chan,

We’re pleased to inform you that your manuscript has been judged scientifically suitable for publication and will be formally accepted for publication once it meets all outstanding technical requirements.

Within one week, you’ll receive an e-mail detailing the required amendments. When these have been addressed, you’ll receive a formal acceptance letter and your manuscript will be scheduled for publication.

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Kind regards,

Vincenzo De Luca

Academic Editor

PLOS ONE

Additional Editor Comments (optional):

Reviewers' comments:

Reviewer's Responses to Questions

Comments to the Author

Reviewer #3: All comments have been addressed

**********

2. Is the manuscript technically sound, and do the data support the conclusions??>

Reviewer #3: Yes

**********

3. Has the statistical analysis been performed appropriately and rigorously? -->?>

Reviewer #3: Yes

**********

4. Have the authors made all data underlying the findings in their manuscript fully available??>

The PLOS Data policy

Reviewer #3: Yes

**********

5. Is the manuscript presented in an intelligible fashion and written in standard English??>

Reviewer #3: Yes

**********

Reviewer #3: I have no further comments. The paper is suitable to be accepted for publication in my opinion.

**********

what does this mean? ). If published, this will include your full peer review and any attached files.

If you choose “no”, your identity will remain anonymous but your review may still be made public.

Do you want your identity to be public for this peer review? For information about this choice, including consent withdrawal, please see our Privacy Policy

Reviewer #3: No

**********

Acceptance letter

Vincenzo De Luca

PONE-D-25-24024R2

PLOS ONE

Dear Dr. Chan,

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on behalf of

Dr. Vincenzo De Luca

Academic Editor

PLOS ONE

Associated Data

    This section collects any data citations, data availability statements, or supplementary materials included in this article.

    Supplementary Materials

    S1 File. Supplementary Tables.

    (DOCX)

    pone.0336918.s001.docx (26.4KB, docx)
    S2 Checklist. Inclusivity in global research questionnaire.

    (DOCX)

    pone.0336918.s002.docx (65.1KB, docx)
    S3 Data. Original dataset used for analyses.

    (XLSX)

    pone.0336918.s003.xlsx (329.2KB, xlsx)
    Attachment

    Submitted filename: Rebuttal letter 20250720.docx

    pone.0336918.s005.docx (22.4KB, docx)

    Data Availability Statement

    All relevant data are available within the paper and its Supporting Information files. We have also uploaded the de-identified data onto the site The Qualitative Data Repository https://qdr.syr.edu/ The DOI is https://doi.org/10.5064/F6JZOYI6. Please also refer to the site https://data.qdr.syr.edu/dataset.xhtml?persistentId=doi%3A10.5064/F6JZOYI6.


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