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Journal of Hip Preservation Surgery logoLink to Journal of Hip Preservation Surgery
. 2025 Dec 22;12(Suppl 2):ii36. doi: 10.1093/jhps/hnaf069.110

AS2.5 A case series of periacetabular osteotomy combined with one-step autologous cartilage regeneration for the treatment of advanced hip disease

Kuei Hsiang Hsu Hsu 1,2, Wen Chieh Chang 3,4, Yu Ping Su 5,6
PMCID: PMC12720649

Abstract

Background

Periacetabular osteotomy (PAO) is a key hip-preserving surgery for conditions such as developmental dysplasia of the hip (DDH) and other hip disorders. However, advanced cartilage loss or osteoarthritis change has traditionally been considered a contraindication. With the advent of 3D modeling and one-step autologous cartilage regeneration, this study explores the potential to extend the indications for hip preservation surgery.

Objective

The case series evaluating the outcomes of PAO combined with one-step autologous cartilage regeneration in patients with advanced cartilage damage or evidence of advanced osteoarthritis change, using 3D model-assisted planning to enhance surgical accuracy and target cartilage defects.

Methodology

This case series included five patients with DDH or Perthes disease and advanced cartilage loss who underwent PAO with one-step autologous cartilage regeneration. Preoperative 3D-printed pelvic models were used for surgical simulation and intraoperative guidance. Clinical outcomes were assessed through radiographic parameters, Harris Hip Score (HHS), and pain scores (VAS), with follow-up extending up to 2 years and minimal with 6 months.

Results

All patients demonstrated radiographic improvement in acetabular coverage and joint alignment. The five patients showed significant improvement in postoperative HHS and VAS pain scores. No major complications were reported, and the clinical improvements were sustained throughout follow-up.

Conclusions

PAO combined with one-step autologous cartilage regeneration, guided by 3D modeling, is a feasible and effective treatment for selected cases of advanced hip disease. This approach broadens surgical indications and offers young patients a promising alternative to total hip arthroplasty.


Articles from Journal of Hip Preservation Surgery are provided here courtesy of Oxford University Press

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