Table 1.
Enzyme replacement therapies licensed for use in the UK
| Treatment | Disease | Annual drug cost for average adult (£) | Cost/QALY (£) | Approximate No of patients in England and Wales |
|---|---|---|---|---|
| Imiglucerase | Gaucher's disease | 90 0008 | 400 0008 | 2508 |
| Agalsidase beta | Fabry's disease | 119 0009 | 252 0009 | 1509 |
| Agalsidase alpha | ||||
| Laronidase | Mucopolysaccharidosis 1* | 450 000† | Not available but >450 000 | 969 |
*
Hurler, Hurler-Scheie, and Scheie's syndromes.
†
Charge to West Midlands region for annual cost of this drug for one patient in 2005 (National Specialist Commissioning Advisory Group, personal communication.)