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. 1951 Apr;48(4):400–406. doi: 10.1042/bj0480400

The metabolism of sulphamezathine, 4:6-dimethylpyrimidine and 2-amino-4:6-dimethylpyrimidine in the rabbit with observations on the hydroxylation of some other sulphonamides

H G Bray 1, H J Lake 1, W V Thorpe 1
PMCID: PMC1275340  PMID: 14838856

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bray H. G., James S. P., Ryman B. E., Thorpe W. V. The fate of certain organic acids and amides in the rabbit: 3. Hydrolysis of amides by enzymes in vitro. Biochem J. 1948;42(2):274–281. [PMC free article] [PubMed] [Google Scholar]
  2. Bray H. G., Lake H. J., Neale F. C., Thorpe W. V., Wood P. B. The fate of certain organic acids and amides in the rabbit: 4. The aminobenzoic acids and their amides. Biochem J. 1948;42(3):434–443. [PMC free article] [PubMed] [Google Scholar]
  3. Bray H. G., Neale F. C., Thorpe W. V. The metabolism of sulphapyridine in the rabbit. Biochem J. 1946;40(3):406–413. doi: 10.1042/bj0400406. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Bray H. G., Ryman B. E., Thorpe W. V. The fate of certain organic acids and amides in the rabbit: 2. p-Hydroxybenzoic acid and its amide. Biochem J. 1947;41(2):212–218. [PMC free article] [PubMed] [Google Scholar]
  5. Bray H. G., Thorpe W. V., White K. The fate of certain organic acids and amides in the rabbit. 10. The application of paper chromatography to metabolic studies of hydroxybenzoic acids and amides. Biochem J. 1950 Mar;46(3):271–275. doi: 10.1042/bj0460271. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Dobson F., Williams R. T. The metabolism of sulphonamides: 1. The metabolism of metanilamide (m-aminobenzenesulphonamide) in the rabbit. Biochem J. 1946;40(2):215–219. [PMC free article] [PubMed] [Google Scholar]
  7. Krebs H. A., Sykes W. O., Bartley W. C. Acetylation and deacetylation of the p-amino group of sulphonamide drugs in animal tissues. Biochem J. 1947;41(4):622–630. doi: 10.1042/bj0410622. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Pryde J., Williams R. T. The biochemistry and physiology of glucuronic acid: The structure of benzoylglucuronic acid. Biochem J. 1933;27(4):1210–1215. doi: 10.1042/bj0271210. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Smith J. N., Williams R. T. The metabolism of sulphonamides: 5. A study of the oxidation and acetylation of sulphonamide drugs and related compounds in the rabbit. Biochem J. 1948;42(3):351–356. doi: 10.1042/bj0420351. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Thorpe W. V., Williams R. T., Shelswell J. Studies in detoxication: On the alleged formation of p-hydroxylaminobenzenesulphonamide and p-aminophenol from sulphanilamide in vivo, on the colour reactions used for their detection, and on the possible formation of aminophenolsulphonamides. Biochem J. 1941 Jan;35(1-2):52–60. doi: 10.1042/bj0350052. [DOI] [PMC free article] [PubMed] [Google Scholar]

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