Abstract
The organism responsible for endocarditis of a prosthetic aortic valve was identified as Nocardia asteroides. The patient was treated with intravenous amikacin (250 mg four times a day) and intravenous imipenem (1.5 g four times a day). The valve was replaced under this new antibiotic regimen. This is the first report of survival after prosthetic valve nocardiosis.
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Selected References
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- Cynamon M. H., Palmer G. S. In vitro susceptibility of Nocardia asteroides to N-formimidoyl thienamycin and several cephalosporins. Antimicrob Agents Chemother. 1981 Dec;20(6):841–842. doi: 10.1128/aac.20.6.841. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Falk R. H., Dimock F. R., Sharkey J. Prosthetic valve endocarditis resulting from Nocardia asteroides. Br Heart J. 1979 Jan;41(1):125–127. doi: 10.1136/hrt.41.1.125. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Gutmann L., Goldstein F. W., Kitzis M. D., Hautefort B., Darmon C., Acar J. F. Susceptibility of Nocardia asteroides to 46 antibiotics, including 22 beta-lactams. Antimicrob Agents Chemother. 1983 Feb;23(2):248–251. doi: 10.1128/aac.23.2.248. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ivert T. S., Dismukes W. E., Cobbs C. G., Blackstone E. H., Kirklin J. W., Bergdahl L. A. Prosthetic valve endocarditis. Circulation. 1984 Feb;69(2):223–232. doi: 10.1161/01.cir.69.2.223. [DOI] [PubMed] [Google Scholar]
- Palmer D. L., Harvey R. L., Wheeler J. K. Diagnostic and therapeutic considerations in Nocardia asteroides infection. Medicine (Baltimore) 1974 Sep;53(5):391–401. doi: 10.1097/00005792-197409000-00005. [DOI] [PubMed] [Google Scholar]
- Stasiecki P., Diehl V., Vlaho M., Krueger G. R., Schaal K. P. Neue erfolgreiche Therapie bei systemischer Infektion mit Nocardia asteroides. Dtsch Med Wochenschr. 1985 Nov 8;110(45):1733–1737. doi: 10.1055/s-2008-1069079. [DOI] [PubMed] [Google Scholar]
- Vlachakis N. D., Gazes P. C., Hairston P. Nocardial endocarditis following mitral valve replacement. Chest. 1973 Feb;63(2):276–278. doi: 10.1378/chest.63.2.276. [DOI] [PubMed] [Google Scholar]
