Abstract
Eight elderly patients (mean (SD) age 72.6 (8.5) years) with severe calcified stenosis of the aortic valve were considered for transluminal balloon dilatation in the Thoraxcenter between March and November 1986. In one patient the procedure could not be performed because of technical difficulties. Balloons of increasing diameter (13-25 mm) were successively passed retrogradely from the femoral artery and manually inflated with pressures of 400-600 kPa (4-6 atmospheres). Post-dilatation, there were significant changes in left ventricular pressures (from 237/21 to 204/13 mm Hg), mean systolic gradient (from 66 to 41 mm Hg, systolic aortic flow (from 172 to 202 ml/s, and aortic valve area (from 0.47 to 0.74 cm2); the cardiac index did not increase significantly (from 2.4 to 2.5 l/min/m2). One patient developed a pseudoaneurysm at the site of the femoral artery puncture that required surgical repair two months after the procedure; one patient experienced an acute left hemianopia during the procedure but had almost completely recovered at discharge. Five patients maintained a clinical improvement at a mean follow up time of 4.5 months after the procedure; two patients underwent aortic valve replacement, one because of minimal haemodynamic improvement after aortic balloon dilatation and persistence of severe dyspnoea and the other because of late recurrence of symptoms caused by restenosis after a successful procedure. Aortic balloon dilatation provides an alternative treatment for patients who are poor surgical candidates for cardiac or extracardiac reasons. At this stage the limited haemodynamic improvements suggest that the treatment can only be regarded as palliative, although proposed technical advances may achieve better immediate results in the future. Long term follow up is needed to evaluate the usefulness of this technique.
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- Arom K. V., Nicoloff D. M., Lindsay W. G., Northrup W. F., Kersten T. E. Should valve replacement and related procedures be performed in elderly patients? Ann Thorac Surg. 1984 Nov;38(5):466–472. doi: 10.1016/s0003-4975(10)64185-9. [DOI] [PubMed] [Google Scholar]
- Cheitlin M. D., Gertz E. W., Brundage B. H., Carlson C. J., Quash J. A., Bode R. S., Jr Rate of progression of severity of valvular aortic stenosis in the adult. Am Heart J. 1979 Dec;98(6):689–700. doi: 10.1016/0002-8703(79)90465-4. [DOI] [PubMed] [Google Scholar]
- Cribier A., Savin T., Saoudi N., Rocha P., Berland J., Letac B. Percutaneous transluminal valvuloplasty of acquired aortic stenosis in elderly patients: an alternative to valve replacement? Lancet. 1986 Jan 11;1(8472):63–67. doi: 10.1016/s0140-6736(86)90716-6. [DOI] [PubMed] [Google Scholar]
- Fenoglio J. J., Jr, McAllister H. A., Jr, DeCastro C. M., Davia J. E., Cheitlin M. D. Congenital bicuspid aortic valve after age 20. Am J Cardiol. 1977 Feb;39(2):164–169. doi: 10.1016/s0002-9149(77)80186-0. [DOI] [PubMed] [Google Scholar]
- Frank S., Johnson A., Ross J., Jr Natural history of valvular aortic stenosis. Br Heart J. 1973 Jan;35(1):41–46. doi: 10.1136/hrt.35.1.41. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Glock Y., Pecoul R., Cerene A., Laguerre J., Puel P. Aortic valve replacement in elderly patients. J Cardiovasc Surg (Torino) 1984 May-Jun;25(3):205–210. [PubMed] [Google Scholar]
- Hochberg M. S., Morrow A. G., Michaelis L. L., McIntosh C. L., Redwood D. R., Epstein S. E. Aortic valve replacement in the elderly. Encouraging postoperative clinical and hemodynamic results. Arch Surg. 1977 Dec;112(12):1475–1480. doi: 10.1001/archsurg.1977.01370120065007. [DOI] [PubMed] [Google Scholar]
- Inoue K., Owaki T., Nakamura T., Kitamura F., Miyamoto N. Clinical application of transvenous mitral commissurotomy by a new balloon catheter. J Thorac Cardiovasc Surg. 1984 Mar;87(3):394–402. [PubMed] [Google Scholar]
- Jackson G., Thomas S., Monaghan M., Forsyth A., Jewitt D. Inoperable aortic stenosis in the elderly: benefit from percutaneous transluminal valvuloplasty. Br Med J (Clin Res Ed) 1987 Jan 10;294(6564):83–86. doi: 10.1136/bmj.294.6564.83. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Lababidi Z. Aortic balloon valvuloplasty. Am Heart J. 1983 Oct;106(4 Pt 1):751–752. doi: 10.1016/0002-8703(83)90097-2. [DOI] [PubMed] [Google Scholar]
- McKay R. G., Safian R. D., Lock J. E., Mandell V. S., Thurer R. L., Schnitt S. J., Grossman W. Balloon dilatation of calcific aortic stenosis in elderly patients: postmortem, intraoperative, and percutaneous valvuloplasty studies. Circulation. 1986 Jul;74(1):119–125. doi: 10.1161/01.cir.74.1.119. [DOI] [PubMed] [Google Scholar]
- Meester G. T., Bernard N., Zeelenberg C., Brower R. W., Hugenholtz P. G. A computer system for real time analysis of cardiac catheterization data. Cathet Cardiovasc Diagn. 1975;1(2):113–132. doi: 10.1002/ccd.1810010203. [DOI] [PubMed] [Google Scholar]
- Pomerance A. Pathogenesis of aortic stenosis and its relation to age. Br Heart J. 1972 Jun;34(6):569–574. doi: 10.1136/hrt.34.6.569. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Quinlan R., Cohn L. H., Collins J. J., Jr Determinants of survival following cardiac operations in elderly patients. Chest. 1975 Oct;68(4):498–500. doi: 10.1378/chest.68.4.498. [DOI] [PubMed] [Google Scholar]
- Roberts W. C., Perloff J. K., Costantino T. Severe valvular aortic stenosis in patients over 65 years of age. A clinicopathologic study. Am J Cardiol. 1971 May;27(5):497–506. doi: 10.1016/0002-9149(71)90412-7. [DOI] [PubMed] [Google Scholar]
- Storstein O., Efskind L. Aortic valve replacement in elderly patients. Acta Med Scand. 1979;206(3):161–164. doi: 10.1111/j.0954-6820.1979.tb13487.x. [DOI] [PubMed] [Google Scholar]
- Walls J. T., Lababidi Z., Curtis J. J., Silver D. Assessment of percutaneous balloon pulmonary and aortic valvuloplasty. J Thorac Cardiovasc Surg. 1984 Sep;88(3):352–356. [PubMed] [Google Scholar]