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. 1976 Jul;40(3):228–240.

Pathological and microbiological observations made on spontaneous cases of acute neonatal calf diarrhea.

M Morin, S Larivière, R Lallier
PMCID: PMC1277758  PMID: 793692

Abstract

The purpose of this report is to describe clinical signs, gross and microscopic lesions, bacteriological and immunofluorescence observations made on spontaneous cases of acute neonatal calf diarrhea (NCD) in dairy and beef herds. The following diagnostic tools were used: 1) direct smears of intestinal content, 2) Escherichia coli counts, 3) aerobic bacterial cultures of the small intestine and other organs (The O serogroup and the enterotoxigenicity of the E. coli isolated was determined), 4) detection of the two Nebraska NCD viruses (reo-like and corona-like) by the fluorescent antibody technique and 5) histological examination on different segments of the digestive tract. The following etiological diagnoses were suggested after post mortem examination of 55 cases of NDC (34 were submitted alive): reo-like virus only (1), reo-like virus + E. coli (4), reo-like virus + cryptosporidium (2), reo- + corona-like viruses (5), reo- + corona-like viruses + cryptosporidium (3), reo- + corona-like viruses + infectious bovine rhinotracheitis virus (1), coronavirus-like agent only (2), coronavirus-like agent + mycotic abomasitis (1), coronavirus-like agent + crytosporidium (1), E. coli only (6), cryptosporidium only (5), mycotic abomasitis (3), mycotic rumenitis + reticulitis (1) and undetermined (20). Most of the calves in the last group were submitted dead.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Acres S. D., Laing C. J., Saunders J. R., Radostits O. M. Acute undifferentiated neonatal diarrhea in beef calves. I. Occurence and distribution of infectious agents. Can J Comp Med. 1975 Apr;39(2):116–132. [PMC free article] [PubMed] [Google Scholar]
  2. BAKER J. A., McENTEE K., GILLESPIE J. H. Effects of infectious bovine rhinotracheitis-infectious pustular vulvovaginitis (IBR-IPV) virus on newborn calves. Cornell Vet. 1960 Apr;50:156–170. [PubMed] [Google Scholar]
  3. Bulmer W. S., Tsai K. S., Little P. B. Adenovirus infection in two calves. J Am Vet Med Assoc. 1975 Feb 1;166(3):233–238. [PubMed] [Google Scholar]
  4. Doughri A. M., Yong S., Storz J. Pathologic changes in intestinal chlamydial infection of newborn calves. Am J Vet Res. 1974 Jul;35(7):939–944. [PubMed] [Google Scholar]
  5. Jervis H. R., Merrill T. G., Sprinz H. Coccidiosis in the guinea pig small intestine due to a Cryptosporidium. Am J Vet Res. 1966 Mar;27(117):408–414. [PubMed] [Google Scholar]
  6. Lambert G., Fernelius A. L. Bovine viral diarrhea virus and Escherichia coli in neonatal calf enteritis. Can J Comp Med. 1968 Apr;32(2):440–446. [PMC free article] [PubMed] [Google Scholar]
  7. Mattson D. E. Naturally occurring infection of calves with a bovine adenovirus. Am J Vet Res. 1973 May;34(5):623–629. [PubMed] [Google Scholar]
  8. Mebus C. A., Kono M., Underdahl N. R., Twiehaus M. J. Cell culture propagation of neonatal calf diarrhea (scours) virus. Can Vet J. 1971 Mar;12(3):69–72. [PMC free article] [PubMed] [Google Scholar]
  9. Mebus C. A., Stair E. L., Rhodes M. B., Twiehaus M. J. Neonatal calf diarrhea: propagation, attenuation, and characteristics of a coronavirus-like agent. Am J Vet Res. 1973 Feb;34(2):145–150. [PubMed] [Google Scholar]
  10. Mebus C. A., Stair E. L., Rhodes M. B., Twiehaus M. J. Pathology of neonatal calf diarrhea induced by a coronavirus-like agent. Vet Pathol. 1973;10(1):45–64. doi: 10.1177/030098587301000105. [DOI] [PubMed] [Google Scholar]
  11. Meuten D. J., Van Kruiningen H. J., Lein D. H. Cryptosporidiosis in a calf. J Am Vet Med Assoc. 1974 Nov 15;165(10):914–917. [PubMed] [Google Scholar]
  12. Moon H. W. Pathogenesis of enteric diseases caused by Escherichia coli. Adv Vet Sci Comp Med. 1974;18(0):179–211. [PubMed] [Google Scholar]
  13. Morin M., Lamothe P., Gagnon A., Malo R. A case of viral neonatal calf diarrhea in a Quebec dairy herd. Can J Comp Med. 1974 Jul;38(3):236–242. [PMC free article] [PubMed] [Google Scholar]
  14. Neitzke J. P., Schiefer B. Incidence of mycotic gastritis in calves up to 30 days of age. Can Vet J. 1974 May;15(5):139–143. [PMC free article] [PubMed] [Google Scholar]
  15. Orskov I., Orskov F., Smith H. W., Sojka W. J. The establishment of K99, a thermolabile, transmissible escherichia coli K antigen, previously called "Kco", possessed by calf and lamb enteropathogenic strains. Acta Pathol Microbiol Scand B. 1975 Feb;83(1):31–36. doi: 10.1111/j.1699-0463.1975.tb00066.x. [DOI] [PubMed] [Google Scholar]
  16. Oxender W. D., Newman L. E., Morrow D. A. Factors influencing dairy calf mortality in Michigan. J Am Vet Med Assoc. 1973 Mar 15;162(6):458–460. [PubMed] [Google Scholar]
  17. Radostits O. M., Rhodes C. S., Mitchell M. E., Spotswood T. P., Wenkoff M. S. A clinical evaluation of antimicrobial agents and temporary starvation in the treatment of acute undifferentiated diarrhea in newborn calves. Can Vet J. 1975 Aug;16(8):219–227. [PMC free article] [PubMed] [Google Scholar]
  18. SLAVIN D. Cryptosporidium meleagridis (sp. nov.). J Comp Pathol. 1955 Jul;65(3):262–266. doi: 10.1016/s0368-1742(55)80025-2. [DOI] [PubMed] [Google Scholar]
  19. SMITH H. W. Observations on the aetiology of neonatal diarrhoea (scours) in calves. J Pathol Bacteriol. 1962 Jul;84:147–168. [PubMed] [Google Scholar]
  20. Smith P. C., Cutlip R. C., Page L. A. Pathogenicity of a strain of Chlamydia psittaci of bovine intestinal origin for neonatal calves. Am J Vet Res. 1973 May;34(5):615–618. [PubMed] [Google Scholar]
  21. Speicher J. A., Hepp R. E. Factors associated with calf mortality in Michigan dairy herds. J Am Vet Med Assoc. 1973 Mar 15;162(6):463–466. [PubMed] [Google Scholar]
  22. Storz J., Eugster A. K., Altera K. P., Olander H. J. Behavior of different bovine chlamydial agents in newborn calves. J Comp Pathol. 1971 Apr;81(2):299–307. doi: 10.1016/0021-9975(71)90104-6. [DOI] [PubMed] [Google Scholar]

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