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. 1979 Oct;295:171–178. doi: 10.1113/jphysiol.1979.sp012959

Cyclic GMP and the permeability of the disks of the frog photoreceptors.

A Caretta, A Cavaggioni, R T Sorbi
PMCID: PMC1278791  PMID: 230335

Abstract

1. The diffusion of sodium, potassium and rubidium (not chloride) ions across the disk membrane is increased by cyclic guanosine monophosphate (cyclic GMP). 2. The increase is greater for sodium than for rubidium in the 0.01-0.1 mM concentration range. 3. Cyclic adenosine monophosphate (cyclic AMP) is less efficient than cyclic GMP; GMP and guanosine triphosphate are without effect. 4. The effect is present with either 1.8 mM calcium ions or 4 mM-EGTA in the perfusion fluid. 5. The presence of the cyclic GMP phosphodiesterase on the disk membranes is not needed for this effect. 6. The effect is present in both unbleached and fully bleached membranes.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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