Abstract
1. Water-loaded rats anaesthetized with ethanol were used for the detection of antidiuretic hormone (ADH). 2. Litter-mates were divided into groups and placed on different diets during the fourth week of life directly after weaning, and maintained on their respective diets for approximately 1 month and their sensitivity to vasopressin was determined. 3. The rats maintained on a diet of only vegetable or vegetable plus casein supplement showed a greater sensitivity to exogenous vasopressin than rats maintained on a standard laboratory diet (pellets). 4. It is proposed that the quantitative relationship between ADH and urine flow is dependent upon the previous history of water consumption.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- DETTELBACH H. R. A method for assaying small amounts of antidiuretic substances with notes on some properties of vasopressin. Am J Physiol. 1958 Feb;192(2):379–386. doi: 10.1152/ajplegacy.1958.192.2.379. [DOI] [PubMed] [Google Scholar]
- DICKER S. E. A method for the assay of very small amounts of antidiuretic activity with a note on the antidiuretic titre of rat's blood. J Physiol. 1953 Oct;122(1):149–157. doi: 10.1113/jphysiol.1953.sp004986. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Forsling M. L., Jones J. J., Lee J. Factors influencing the sensitivity of the rat to vasopressin. J Physiol. 1968 May;196(2):495–505. doi: 10.1113/jphysiol.1968.sp008520. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Gupta K. K., Chaudhury R. R., Chhuttani P. N. Plasma antidiuretic hormone concentrations in normal subjects and in persons with oedema of cardiac and renal origin, and in normal pregnancy. Indian J Med Res. 1967 Jun;55(6):643–651. [PubMed] [Google Scholar]
- HENDRIKX A., EPSTEIN F. H. Effect of feeding protein and urea on renal concentrating ability in the rat. Am J Physiol. 1958 Dec;195(3):539–542. doi: 10.1152/ajplegacy.1958.195.3.539. [DOI] [PubMed] [Google Scholar]
- LITTLE J. B., RADFORD E. P., Jr BIO-ASSAY FOR ANTIDIURETIC ACTIVITY IN BLOOD OF UNDISTURBED RATS. J Appl Physiol. 1964 Mar;19:179–186. doi: 10.1152/jappl.1964.19.2.179. [DOI] [PubMed] [Google Scholar]
- RADFORD E. P., Jr Factors modifying water metabolism in rats fed dry diets. Am J Physiol. 1959 May;196(5):1098–1108. doi: 10.1152/ajplegacy.1959.196.5.1098. [DOI] [PubMed] [Google Scholar]
- YOSHIDA S., MOTOHASHI K., IBAYASHI H., OKINAKA S. METHOD FOR THE ASSAY OF ANTIDIURETIC HORMONE IN PLASMA WITH A NOTE ON THE ANTIDIURETIC TITER OF HUMAN PLASMA. J Lab Clin Med. 1963 Aug;62:279–285. [PubMed] [Google Scholar]