Abstract
We have observed Brillouin-like low frequency collective modes in the scattering of 1 A neutrons from a fully in vivo deuterated protein. These modes are tentatively interpreted as due to short-lived coherent excitations propagating with velocities between 2,000 and 4,000 m/s in elements of the secondary structure and patches of closely associated water.
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Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Chou K. C. Low-frequency motions in protein molecules. Beta-sheet and beta-barrel. Biophys J. 1985 Aug;48(2):289–297. doi: 10.1016/S0006-3495(85)83782-6. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Fisher R. G., Woods N. E., Fuchs H. E., Sweet R. M. Three-dimensional structures of C-phycocyanin and B-phycoerythrin at 5-A resolution. J Biol Chem. 1980 Jun 10;255(11):5082–5089. [PubMed] [Google Scholar]
- Grimm H, Stiller H, Majkrzak CF, Rupprecht A, Dahlborg U. Observation of acoustic umklapp-phonons in water-stabilized DNA by neutron scattering. Phys Rev Lett. 1987 Oct 12;59(15):1780–1783. doi: 10.1103/PhysRevLett.59.1780. [DOI] [PubMed] [Google Scholar]
- Harley R., James D., Miller A., White J. W. Phonons and the elastic moduli of collagen and muscle. Nature. 1977 May 19;267(5608):285–287. doi: 10.1038/267285a0. [DOI] [PubMed] [Google Scholar]
- Lawrence A. F., McDaniel J. C., Chang D. B., Birge R. R. The nature of phonons and solitary waves in alpha-helical proteins. Biophys J. 1987 May;51(5):785–793. doi: 10.1016/S0006-3495(87)83405-7. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Middendorf H. D. Biophysical applications of quasi-elastic and inelastic neutron scattering. Annu Rev Biophys Bioeng. 1984;13:425–451. doi: 10.1146/annurev.bb.13.060184.002233. [DOI] [PubMed] [Google Scholar]
- Schirmer T., Bode W., Huber R., Sidler W., Zuber H. X-ray crystallographic structure of the light-harvesting biliprotein C-phycocyanin from the thermophilic cyanobacterium Mastigocladus laminosus and its resemblance to globin structures. J Mol Biol. 1985 Jul 20;184(2):257–277. doi: 10.1016/0022-2836(85)90379-1. [DOI] [PubMed] [Google Scholar]
- Yang P. H., Rupley J. A. Protein--water interactions. Heat capacity of the lysozyme--water system. Biochemistry. 1979 Jun 12;18(12):2654–2661. doi: 10.1021/bi00579a035. [DOI] [PubMed] [Google Scholar]