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. 1979 Sep;294:349–364. doi: 10.1113/jphysiol.1979.sp012934

Processing of eye movement signals in the flocculus of the monkey.

H Noda, D A Suzuki
PMCID: PMC1280561  PMID: 117102

Abstract

1. Extracellular recordings were made from afferents to the Purkinje cells of the flocculus of monkeys either spontaneously making saccadic eye movements (saccades) or trained to fixate a small visual target projected on a tangent screen. In the trained monkeys, saccades of known magnitude and direction were induced by changing the position of the fixation target. 2. Among a population of 108 units, eight were climbing fibres, seventy-one were mossy fibres, and twenty-nine were non-Purkinje cells. Based on their discharge patterns the latter two groups of units were categorized into one of four classes. 3. Long-lead burst units (twenty-two units) exhibited saccade-related discharges substantially before saccade onset (average: 113 msec). Most of these (twenty units) discharged for saccades in a particular direction, while the remainder exhibited discharges for saccades in all directions. All units were essentially silent between saccades. 4. Burst units (twenty-seven units) started discharging slightly before saccades (average: 6.9 msec). Discharges were associated with saccades in all directions (sixteen units) or in preferred directions (eleven units) and were not observed during periods of fixation. 5. Burst-tonic units (twenty-two units) were characterized by saccade-related burst and position-related intersaccadic tonic activity. 6. Tonic units (thirty-seven units) exhibited position-related tonic activity. The position-related activity in both burst-tonic and tonic units was observed only for fixation points within a specified region. The units were silent for fixation positions outside this region of preferred fixation.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Alley K., Baker R., Simpson J. I. Afferents to the vestibulo-cerebellum and the origin of the visual climbing fibers in the rabbit. Brain Res. 1975 Nov 21;98(3):582–589. doi: 10.1016/0006-8993(75)90375-3. [DOI] [PubMed] [Google Scholar]
  2. Angaut P., Brodal A. The projection of the "vestibulocerebellum" onto the vestibular nuclei in the cat. Arch Ital Biol. 1967 Nov;105(4):441–479. [PubMed] [Google Scholar]
  3. Baker R., Gresty M., Berthoz A. Neuronal activity in the prepositus hypoglossi nucleus correlated with vertical and horizontal eye movement in the cat. Brain Res. 1976 Jan 16;101(2):366–371. doi: 10.1016/0006-8993(76)90278-x. [DOI] [PubMed] [Google Scholar]
  4. Brodal A. Vestibulocerebellar input in the cat: anatomy. Prog Brain Res. 1972;37:315–327. doi: 10.1016/S0079-6123(08)63910-2. [DOI] [PubMed] [Google Scholar]
  5. Fuchs A. F., Kimm J. Unit activity in vestibular nucleus of the alert monkey during horizontal angular acceleration and eye movement. J Neurophysiol. 1975 Sep;38(5):1140–1161. doi: 10.1152/jn.1975.38.5.1140. [DOI] [PubMed] [Google Scholar]
  6. Gresty M., Baker R. Neurons with visual receptive field, eye movement and neck displacement sensitivity within and around the nucleus prepositus hypoglossi in the alert cat. Exp Brain Res. 1976 Feb 26;24(4):429–433. doi: 10.1007/BF00235008. [DOI] [PubMed] [Google Scholar]
  7. Kawamura K., Brodal A., Hoddevik G. The projection of the superior colliculus onto the reticular formation of the brain stem. An experimental anatomical study in the cat. Exp Brain Res. 1974 Jan 22;19(1):1–19. doi: 10.1007/BF00233392. [DOI] [PubMed] [Google Scholar]
  8. Keller E. L., Daniels P. D. Oculomotor related interaction of vestibular and visual stimulation in vestibular nucleus cells in alert monkey. Exp Neurol. 1975 Jan;46(1):187–198. doi: 10.1016/0014-4886(75)90041-2. [DOI] [PubMed] [Google Scholar]
  9. Keller E. L. Participation of medial pontine reticular formation in eye movement generation in monkey. J Neurophysiol. 1974 Mar;37(2):316–332. doi: 10.1152/jn.1974.37.2.316. [DOI] [PubMed] [Google Scholar]
  10. Kotchabhakdi N., Walberg F. Cerebeller afferents from neurons in motor nuclei of cranial nerves demonstrated by retrograde axonal transport of horseradish peroxidase. Brain Res. 1977 Nov 25;137(1):158–163. doi: 10.1016/0006-8993(77)91020-4. [DOI] [PubMed] [Google Scholar]
  11. Lisberger S. G., Fuchs A. F. Role of primate flocculus during rapid behavioral modification of vestibuloocular reflex. II. Mossy fiber firing patterns during horizontal head rotation and eye movement. J Neurophysiol. 1978 May;41(3):764–777. doi: 10.1152/jn.1978.41.3.764. [DOI] [PubMed] [Google Scholar]
  12. Luschei E. S., Fuchs A. F. Activity of brain stem neurons during eye movements of alert monkeys. J Neurophysiol. 1972 Jul;35(4):445–461. doi: 10.1152/jn.1972.35.4.445. [DOI] [PubMed] [Google Scholar]
  13. Maekawa K., Simpson J. I. Climbing fiber responses evoked in vestibulocerebellum of rabbit from visual system. J Neurophysiol. 1973 Jul;36(4):649–666. doi: 10.1152/jn.1973.36.4.649. [DOI] [PubMed] [Google Scholar]
  14. Miles F. A. Single unit firing patterns in the vestibular nuclei related to voluntary eye movements and passive body rotation in conscious monkeys. Brain Res. 1974 May 17;71(2-3):215–224. doi: 10.1016/0006-8993(74)90963-9. [DOI] [PubMed] [Google Scholar]
  15. Noda H., Suzuki D. A. The role of the flocculus of the monkey in fixation and smooth pursuit eye movements. J Physiol. 1979 Sep;294:335–348. doi: 10.1113/jphysiol.1979.sp012933. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Noda H., Suzuki D. A. The role of the flocculus of the monkey in saccadic eye movements. J Physiol. 1979 Sep;294:317–334. doi: 10.1113/jphysiol.1979.sp012932. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Raybourn M. S., Keller E. L. Colliculoreticular organization in primate oculomotor system. J Neurophysiol. 1977 Jul;40(4):861–878. doi: 10.1152/jn.1977.40.4.861. [DOI] [PubMed] [Google Scholar]
  18. Schiller P. H., Koerner F. Discharge characteristics of single units in superior colliculus of the alert rhesus monkey. J Neurophysiol. 1971 Sep;34(5):920–936. doi: 10.1152/jn.1971.34.5.920. [DOI] [PubMed] [Google Scholar]
  19. Simpson J. I., Precht W., Llinás R. Sensory separation in climbing and mossy fiber inputs to cat vestibulocerebellum. Pflugers Arch. 1974;351(3):183–193. doi: 10.1007/BF00586917. [DOI] [PubMed] [Google Scholar]
  20. Wurtz R. H., Goldberg M. E. Activity of superior colliculus in behaving monkey. 3. Cells discharging before eye movements. J Neurophysiol. 1972 Jul;35(4):575–586. doi: 10.1152/jn.1972.35.4.575. [DOI] [PubMed] [Google Scholar]

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