Lu Zou
Lu Zou
1Department of Oncology, Nanjing Drum Tower Hospital, Clinical College of Nanjing Drum Tower Hospital, Nanjing University of Chinese Medicine, Nanjing, China
2The Comprehensive Cancer Center of Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China
Writing – original draft
1,2,†,
Jingjing Chen
Jingjing Chen
1Department of Oncology, Nanjing Drum Tower Hospital, Clinical College of Nanjing Drum Tower Hospital, Nanjing University of Chinese Medicine, Nanjing, China
2The Comprehensive Cancer Center of Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China
Writing – review & editing
1,2,†,
Xinyuan Bai
Xinyuan Bai
1Department of Oncology, Nanjing Drum Tower Hospital, Clinical College of Nanjing Drum Tower Hospital, Nanjing University of Chinese Medicine, Nanjing, China
2The Comprehensive Cancer Center of Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China
Writing – review & editing
1,2,
Yingxin Wang
Yingxin Wang
1Department of Oncology, Nanjing Drum Tower Hospital, Clinical College of Nanjing Drum Tower Hospital, Nanjing University of Chinese Medicine, Nanjing, China
3Department of Laboratory Medicine, Nanjing Drum Tower Hospital, Clinical College of Nanjing Medical University, Nanjing, China
Writing – review & editing
1,3,
Changchang Lu
Changchang Lu
4Institute of Translational Medicine, Zhejiang University, Hangzhou, China
Writing – review & editing
4,
Qiaoli Wang
Qiaoli Wang
1Department of Oncology, Nanjing Drum Tower Hospital, Clinical College of Nanjing Drum Tower Hospital, Nanjing University of Chinese Medicine, Nanjing, China
Writing – review & editing
1,
Subiyinuer Tuerhong
Subiyinuer Tuerhong
1Department of Oncology, Nanjing Drum Tower Hospital, Clinical College of Nanjing Drum Tower Hospital, Nanjing University of Chinese Medicine, Nanjing, China
3Department of Laboratory Medicine, Nanjing Drum Tower Hospital, Clinical College of Nanjing Medical University, Nanjing, China
Writing – review & editing
1,3,
Mengzhu Li
Mengzhu Li
2The Comprehensive Cancer Center of Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China
Writing – review & editing
2,
Qinghua Zheng
Qinghua Zheng
3Department of Laboratory Medicine, Nanjing Drum Tower Hospital, Clinical College of Nanjing Medical University, Nanjing, China
Writing – review & editing
3,
Fanyan Meng
Fanyan Meng
1Department of Oncology, Nanjing Drum Tower Hospital, Clinical College of Nanjing Drum Tower Hospital, Nanjing University of Chinese Medicine, Nanjing, China
3Department of Laboratory Medicine, Nanjing Drum Tower Hospital, Clinical College of Nanjing Medical University, Nanjing, China
5State Key Laboratory of Analytical Chemistry for Life Sciences, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, China
Writing – review & editing
1,3,5,*,
Juan Du
Juan Du
1Department of Oncology, Nanjing Drum Tower Hospital, Clinical College of Nanjing Drum Tower Hospital, Nanjing University of Chinese Medicine, Nanjing, China
2The Comprehensive Cancer Center of Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China
Writing – review & editing
1,2,*
1Department of Oncology, Nanjing Drum Tower Hospital, Clinical College of Nanjing Drum Tower Hospital, Nanjing University of Chinese Medicine, Nanjing, China
2The Comprehensive Cancer Center of Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China
3Department of Laboratory Medicine, Nanjing Drum Tower Hospital, Clinical College of Nanjing Medical University, Nanjing, China
4Institute of Translational Medicine, Zhejiang University, Hangzhou, China
5State Key Laboratory of Analytical Chemistry for Life Sciences, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, China
*Correspondence: Fanyan Meng, fanyanmeng@hotmail.com; Juan Du, dujuanglyy@163.com
†These authors have contributed equally to this work
Roles
Lu Zou: Writing – original draft
Jingjing Chen: Writing – review & editing
Xinyuan Bai: Writing – review & editing
Yingxin Wang: Writing – review & editing
Changchang Lu: Writing – review & editing
Qiaoli Wang: Writing – review & editing
Subiyinuer Tuerhong: Writing – review & editing
Mengzhu Li: Writing – review & editing
Qinghua Zheng: Writing – review & editing
Fanyan Meng: Writing – review & editing
Juan Du: Writing – review & editing
Received 2025 Dec 23; Accepted 2025 Dec 23; Revised 2025 Dec 22; Collection date 2025.
Keywords: KRAS G12V, bispecific T-cell engager (BiTE), IRGD, pancreatic cancer, T-cell infiltration
Copyright © 2026 Zou, Chen, Bai, Wang, Lu, Wang, Tuerhong, Li, Zheng, Meng and Du.
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