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. 1980 May;302:535–547. doi: 10.1113/jphysiol.1980.sp013259

The effect of contrast on the non-linear response of the Y cell.

R M Shapley, J D Victor
PMCID: PMC1282864  PMID: 7411468

Abstract

1. Second-order frequency responses were obtained from cat retinal ganglion cells of the Y type. The cells were stimulated by a spatial sine grating whose contrast was modulated in time by a sum of eight sinusoids. 2. Second-order frequency responses obtained at higher contrasts have a peak amplitude at higher input temporal frequency, and phase shifts, compared to their low-contrast counterparts. 3. This change in shape of the second-order frequency response is a departure from the prediction of the linear/static non-linear/linear sandwich model of the non-linear pathway in the cat retina. The departure is analysed by means of the hypothesis that the two filters of the sandwich model are parametric in contrast. 4. Most of the change in shape of the second-order frequency response with contrast is accounted for in terms of the sandwich model by changes in the transfer characteristics of the filter preceding the static non-linearity. 5. The effect of contrast on the second-order responses of Y cells is qualitatively similar in several ways to the effect of contrast on first-order responses. This suggests that the contrast gain control mechanism acts early in the retina, before linear and non-linear pathways have diverged.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Enroth-Cugell C., Robson J. G. The contrast sensitivity of retinal ganglion cells of the cat. J Physiol. 1966 Dec;187(3):517–552. doi: 10.1113/jphysiol.1966.sp008107. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Hochstein S., Shapley R. M. Linear and nonlinear spatial subunits in Y cat retinal ganglion cells. J Physiol. 1976 Nov;262(2):265–284. doi: 10.1113/jphysiol.1976.sp011595. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Hochstein S., Shapley R. M. Quantitative analysis of retinal ganglion cell classifications. J Physiol. 1976 Nov;262(2):237–264. doi: 10.1113/jphysiol.1976.sp011594. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Kolb H., West R. W. Synaptic connections of the interplexiform cell in the retina of the cat. J Neurocytol. 1977 Apr;6(2):155–170. doi: 10.1007/BF01261503. [DOI] [PubMed] [Google Scholar]
  5. Levick W. R. Another tungsten microelectrode. Med Biol Eng. 1972 Jul;10(4):510–515. doi: 10.1007/BF02474199. [DOI] [PubMed] [Google Scholar]
  6. Levick W. R. Form and function of cat retinal ganglion cells. Nature. 1975 Apr 24;254(5502):659–662. doi: 10.1038/254659a0. [DOI] [PubMed] [Google Scholar]
  7. Marmarelis P. Z., Naka K. White-noise analysis of a neuron chain: an application of the Wiener theory. Science. 1972 Mar 17;175(4027):1276–1278. doi: 10.1126/science.175.4027.1276. [DOI] [PubMed] [Google Scholar]
  8. Naka K., Marmarelis P. Z., Chan R. Y. Morphological and functional identifications of catfish retinal neurons. III. Functional identification. J Neurophysiol. 1975 Jan;38(1):92–131. doi: 10.1152/jn.1975.38.1.92. [DOI] [PubMed] [Google Scholar]
  9. Shapley R. M., Victor J. D. Nonlinear spatial summation and the contrast gain control of cat retinal ganglion cells. J Physiol. 1979 May;290(2):141–161. doi: 10.1113/jphysiol.1979.sp012765. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Shapley R. M., Victor J. D. The effect of contrast on the transfer properties of cat retinal ganglion cells. J Physiol. 1978 Dec;285:275–298. doi: 10.1113/jphysiol.1978.sp012571. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Victor J. D., Shapley R. M., Knight B. W. Nonlinear analysis of cat retinal ganglion cells in the frequency domain. Proc Natl Acad Sci U S A. 1977 Jul;74(7):3068–3072. doi: 10.1073/pnas.74.7.3068. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Victor J. D., Shapley R. M. Receptive field mechanisms of cat X and Y retinal ganglion cells. J Gen Physiol. 1979 Aug;74(2):275–298. doi: 10.1085/jgp.74.2.275. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Victor J. D., Shapley R. M. The nonlinear pathway of Y ganglion cells in the cat retina. J Gen Physiol. 1979 Dec;74(6):671–689. doi: 10.1085/jgp.74.6.671. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Werblin F. S., Dowling J. E. Organization of the retina of the mudpuppy, Necturus maculosus. II. Intracellular recording. J Neurophysiol. 1969 May;32(3):339–355. doi: 10.1152/jn.1969.32.3.339. [DOI] [PubMed] [Google Scholar]

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