Table 5.
Best estimate
|
||||
---|---|---|---|---|
Observed | Expected | Standardised risk ratio† | Plausible range of standardised risk ratio‡ | |
Deaths from colorectal cancer
|
(followed to 31 December 2002)
|
|
||
Moderate risk | 2 | 10.7 | 0.19** | 0.10***-0.38 |
Group 4§ | 3 | 10.9 | 0.28* | 0.20***-0.59 |
Cases of colorectal cancer
|
|
|
|
|
Between first and last colonoscopy (excluding those detected on first colonoscopy)
| ||||
Moderate risk | 1 | 13.4 | 0.08*** | 0.04***-0.15* |
Group 4§ | 8 | 16.5 | 0.49* | 0.35***-1.04 |
In individuals followed for at least 3 years (to 31 December 2001)
|
|
|||
Moderate risk | 4 | 19.9 | 0.20*** | 0.11***-0.41 |
Group 4§ | 11 | 19.2 | 0.57 | 0.41***-1.23 |
In individuals followed for at least 3 years (to 31 December 2003)
|
|
|||
Moderate risk | 4 | 26.5 | 0.15*** | 0.08***-0.30** |
Group 4§ | 11 | 26.6 | 0.41** | 0.30***-0.89 |
*One sided P<0.025. **One sided P<0.005. ***One sided P<0.0005.
Standardised risk ratio: O/E=observed/expected.
O/E based on the expected number of cases when the highest and the lowest reasonable values for the familial risk are used.
Families meeting the Amsterdam criteria.