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. 2026 Feb 2;16:4475. doi: 10.1038/s41598-026-36362-z

Correction: Dual-enzyme activated theranostic nanoparticles for image-guided glioblastoma therapy

Zahra Shokri Varniab 1, Edwin Chang 1,2, Jie Wang 1, Ramesh Duwa 1, Vidyani Suryadevara 1, Wei Wu 1, Manoj Kumar 1, Tie Liang 1, Zubeda Khatoon 3, Goreti Ribeiro Morais 3, Robert Falconer 3, Yifeng Shi 4, Grigory Tikhomirov 4, Kerem Nernekli 1, Laura Jean Pisani 1, Heike Elisabeth Daldrup-Link 1,5,
PMCID: PMC12865017  PMID: 41629557

Correction to: Scientific Reports 10.1038/s41598-025-97775-w, published online 19 April 2025

The original version of this Article contained an error where an incorrect version of Fig. 9 was published. Specifically, Panels B and F inadvertently display H&E images from a different experimental group than indicated and the magnification across panels is inconsistent.

Fig. 9.

Fig. 9

Prussian blue iron stains of GBM39 tumors after theranostic therapy. (A,C,E) Representative Prussian blue (PB) stained tumor sections from the combination therapy group, monotherapy group, and control group at 48 h after intravenous injections. Scale bar: 100 μm; magnification: × 20. (G) Quantitative analysis of Prussian blue-positive staining area. Box plots illustrate the proportion of positively stained areas relative to the total tumor area (%) for each group (n = 4 mice in each group). Statistical comparison of PB-positive staining between the combination therapy group and monotherapy group was performed using the Mann–Whitney U test. The control group showed no detectable PB staining and was excluded from statistical analysis. (B,D,F) Representative hematoxylin and eosin (H&E) stained tumor sections from the combination therapy, monotherapy, and control groups, respectively. We did not observe any significant intra-tumoral hemorrhage in response to TNP treatment.

The original Fig. 9 and accompanying legend appear below.

The original Article has been corrected.


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