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. 2026 Jan 21;17:1784968. doi: 10.3389/fimmu.2026.1784968

Correction: The clinical and pathological significance of tertiary lymphoid structure in extramammary Paget’s disease

Ningyuan Xi 1,, Xiaoxiang Xu 1,, Mingyuan Xu 1, Nanhui Wu 1, Yuhao Wu 2, Jiashe Chen 1, Shuyi Liu 1, Long Jiang 3, Guorong Yan 2, Guolong Zhang 2,*, Yeqiang Liu 1,*
PMCID: PMC12869717  PMID: 41646857

There was a mistake in Figure 1 as published. Figure 1A demonstrated the volcano plot regarding extramammary Paget’s disease (EMPD) vs. normal skin (NS) analyzed from GSE117285 data, which was an old version and the 10 significant chemokines were not highlighted. Therefore, we have highlighted the 10 significant chemokines in the new volcano plot of Figure 1A using the GSE117285 data. The corrected Figure 1 appears below.

Figure 1.

Three-part data visualization: A) Volcano plot showing gene expression. Red points indicate upregulation in EMPD, teal points in NS, and gray points are stable, with gene labels such as CXCL1 and CCL8 highlighted. B) Heatmap displaying gene expression levels across samples and groups (EMPD and NS) with a color gradient from blue to red indicating expression levels, along with a hierarchical clustering dendrogram. C) Box plots of mRNA expression for genes like CXCL1, CXCL2, CXCL9, and others, comparing EMPD and NS groups, with higher expression in EMPD for several genes.

IME composition of EMPD and NS tissues in GSE117285. (A) Volcano plot for differentially expressed analysis in EMPD vs. NS tissue. (B) The IME composition in EMPD and NS tissues analyzed by the MCP-counter. NK cells, natural killer cells. (C) Differential expression of TLS-related chemokines in EMPD and NS tissue. NS, normal skin.

The original version of this article has been updated.

Footnotes

Edited and reviewed by: Noha Mousaad Elemam, University of Sharjah, United Arab Emirates

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