In the August 2000 issue of the Journal, in the article “An Optimized Set of Human Telomere Clones for Studying Telomere Integrity and Architecture,” by Knight et al. (67:320–332), the two rows listing data for 18p were inadvertently deleted from the bottom of the first page of table 1 (p. 324); the publisher regrets this error. In addition, the clone type for 5p clone ID GS-24-H17 should be PAC (not BAC), and the source BAC libraries for 22q and XpYp should be CTD-3018-K1 and RPCI-11-839-D20, respectively (not GS-3018-K1 and GS-839-D20); the authors regret these errors. The corrected table (in which the missing rows are indicated by bold type and in which the other changes are underlined) is provided below.
Table 1.
Second-Generation Telomere Clones and Their Location
| Telomere | Clone ID | CloneType | MaximumPhysicalDistancefromTelomere(kb) | Method | Fiber-FISH (kb)a | RHMapping(cR)b | Marker |
| 1p | GS-62-L8 | PAC | 200 | Interphase mapping from subtelomeric sequences | 7.69 tel | 1PTEL06 | |
| GS-232-B23 | BAC | 200 | Interphase mapping from subtelomeric sequences | CEB108/T7 | |||
| 1q | GS-160-H23 | PAC | 80 | Contig | <50 | 1QTEL19 | |
| GS-167-K11 | BAC | 270 | RARE from YAC end sequence | 1QTEL10, 1QTEL19, VIJ-YRM2123 | |||
| 2p | GS-892-G20 | PAC | 330 | RARE from YAC end sequence | 2PTEL27 | ||
| GS-8-L3 | BAC | 330 | RARE from YAC end sequence | VIJ-YRM2052 | |||
| 2q | GS-1011-O17 | PAC | 240 | RARE from YAC end sequence | 2QTEL47 | ||
| RG-172-I13 | BAC | 240 | RARE from YAC end sequence | VIJ-YRM2112 | |||
| 3p | GS-1186-B18 | PAC | 450 | RARE from YAC end sequence | 150–250 | 3PTEL25 | |
| RG-228-K22 | BAC | 450 | RARE from YAC end sequence | 3PTEL25 | |||
| 3q | 196-F4 | PAC | 450 | YAC clone size | 3QTEL06 | ||
| GS-56-H22 | BAC | 450 | YAC clone size | 3QTEL05 | |||
| 4p | GS-36-P21 | PAC | 73 | Sequence: Z95704 | 80–100 | 4PTEL04 | |
| GS-118-B13 | BAC | 101 | Sequence: Z95704; walk from 4PTEL01 | GS10K2/T7 | |||
| 4q | GS-963-K6 | PAC | 275–500 | Contig (vanGeel et al. 1999) | 2.9 tel | 4QTEL11 | |
| GS-31-J3 | BAC | 300–700c | Interphase distance from 4QTEL11 | AFMA224XH1 | |||
| 5p | GS-189-N21 | PAC | Unknown | 16.2 cen | 5PTEL48 | ||
| GS-24-H17 | PAC | Unknown | Distal marker of 5p contig | C84C11/T3 | |||
| 5q | GS-240-G13 | PAC | 245 | YAC clone size | 5QTEL70 | ||
| 6p | GS-62-I11 | PAC | 300 | Fiber FISH | <300 | 19.3 cen | 6PTEL48 |
| GS-196-I5 | BAC | 300 | 6PTEL48 | ||||
| 6q | GS-57-H24 | PAC | 280 | RARE from YAC end sequence | 6QTEL54 | ||
| 7p | GS-164-D18 | PAC | 255 | YAC clone size | ∼130 | 5.76 cen | 7PTEL03, VIJ-YRM2185 |
| 7q | GS-3K-23 | PAC | 7 | Sequence: AF027390 | 7QTEL20, VIJ-YRM2000 | ||
| 8p | GS-580-L5d | PAC | 250 | YAC clone size | NP | 8PTEL91 | |
| GS-77-L23 | BAC | 250–450c | Interphase distance from 8PTEL91 | AFM197XG5 | |||
| 8q | GS-489-D14 | PAC | 170 | RARE from YAC end sequence | 8QTEL11 | ||
| GS-261-I1 | BAC | 170 | RARE from YAC end sequence | VIJ-YRM2053 | |||
| 9p | GS-43-N6 | PAC | 600 | YAC clone size | <600 | 13.9 tel | 9PTEL30 |
| RG-41-L13 | BAC | 190 | YAC clone size | 305J7-T7 | |||
| 9q | GS-112-N13d | PAC | 65 | YAC clone size | NP | 9QTEL33 | |
| GS-135-I17 | BAC | 65 | YAC clone size | VIJ-YRM2241 | |||
| 10p | GS-306-F7 | PAC | 320 | YAC clone size | ∼100 | 10PTEL45 | |
| GS-23-B11 | BAC | 320 | YAC clone size | 10PTEL006 | |||
| 10q | GS-137-E24 | PAC | 270 | YAC clone size | ∼100 | 10QTEL24 | |
| GS-261-B16 | BAC | 270 | YAC clone size | 10QTEL24 | |||
| 11p | GS-908-H22d | PAC | 125 | YAC clone size | NP | 11PTEL03 | |
| GS-44-H16 | PAC | 125 | YAC clone size | VIJ-YRM2209 | |||
| 11q | GS-770-G7d | PAC | 65 | YAC clone size | NP | 11QTEL38 | |
| GS-26-N8 | PAC | 65 | YAC clone size | VIJ-YRM2072 | |||
| 12p | GS-496-A11d | PAC | Unknown | TTAGGG clone | NP | 27.8 cen | 12PTEL27 |
| GS-8-M16d | BAC | 100 | YAC clone size | TYAC-14 | |||
| GS-124-K20 | BAC | 100 | YAC clone size | 8M16/SP6 | |||
| 12q | GS-221-K18 | PAC | 190 | RARE from YAC end sequence | 100/600e | 12QTEL87, VIJ-YRM2196 | |
| 13q | GS-163-C9 | PAC | 170 | RARE from YAC end sequence | <20 | 13QTEL56 | |
| GS-1-L16 | PAC | 170 | RARE from YAC end sequence | VIJ-YRM2002 | |||
| 14q | GS-820-M16 | PAC | 200 | RARE from YAC end sequence | 14QTEL01 | ||
| GS-200-D12 | BAC | 200 | RARE from YAC end sequence | VIJ-YRM2006 | |||
| 15q | GS-124-05d | PAC | 300c | Interphase mapping from 15q YAC | NP | 24.46 tel | 15QTEL56 |
| GS-154-P1 | PAC | 300c | Interphase mapping from 15q YAC | WI-5214 | |||
| 16p | GS-121-I4 | PAC | 160 | Sequence: Z84721 | 16PTEL05 | ||
| RG-191-K2 | BAC | 160 | Sequence: Z84721 | 16PTEL05 | |||
| 16q | GS-240-G10 | PAC | 200 | YAC clone size | 17.91 tel | 16QTEL48 | |
| GS-191-P24 | PAC | 200 | YAC clone size | 16QTEL13 | |||
| 17p | GS-202-L17d | PAC | 60 | Contig (Xiang et al. 1999) | 30/100e | 17PTEL80 | |
| GS-68-F18 | BAC | 100–200 | Walk from 17PTEL80 | 282M15/SP6 | |||
| 17q | GS-362-K4d | PAC | 90 | YAC clone size | NP | 17QTEL13 | |
| GS-50-C4 | BAC | 100–300 | Interphase distance from 17QTEL13 | AFM217YD10 | |||
| 18p | GS-52-M11 | P1 | 220 | RARE from YAC end sequence | 18PTEL02 | ||
| GS-74-G18 | BAC | 220 | RARE from YAC end sequence | VIJ-YRM2102 | |||
| 18q | GS-964-M9 | PAC | 290 | RARE from YAC end sequence | 18QTEL11 | ||
| GS-75-F20 | BAC | 290 | RARE from YAC end sequence | VIJ-YRM2050 | |||
| 19p | GS-546-C11 | PAC | 250–500 | LLNL chromosome 19 contig | NP | 16.13 tel | 19PTEL29 |
| RG-129-F16 | BAC | 250–500 | LLNL chromosome 19 contig | 129F16/SP6 | |||
| 19q | GS-48-O23 | PAC | 250–500 | LLNL chromosome 19 contig | 11.65 tel | 19QTEL12 | |
| GS-325-I23 | BAC | 250–500 | LLNL chromosome 19 contig | D19S238E | |||
| 20p | GS-1061-L1 | PAC | 180 | YAC clone size | 20PTHY33 | ||
| GS-82-O2 | PAC | 180 | YAC clone size | 20PTEL18 | |||
| 20q | GS-81-F12d | PAC | 50 | Fiber FISH | <50 | 28.2 tel | 20QTEL14 |
| 21q | GS-63-H24 | PAC | 175 | RARE from YAC end sequence | 21QTEL07 | ||
| GS-2-H14d | P1 | 175 | RARE from YAC end sequence | VIJ-YRM2029 | |||
| 22q | GS-99-K24d | PAC | 120 | Sequence: (Dunham et al. 1999) | 150–200 | 12.6 tel | 22QTEL31 |
| CITD-3018-K1 | BAC | 155 | Sequence: (Dunham et al. 1999) | 3018K1/T7 | |||
| XpYp | GS-98-C4 | PAC | 490 | STS map (Nagaraja et al. 1997) | DXYS28 | ||
| RPCI-11-839-D20 | BAC | 160 | STS map (Nagaraja et al. 1997) | DXYS129 | |||
| XqYq | GS-225-F6 | BAC | 100 | CDY16C07 | |||
| Xq | GS-202-M24 | PAC | 500 | STS map (Nagaraja et al. 1997) | DXS7059 |
NP = not possible, because of cross-hybridization.
cen = centromeric; tel = telomeric.
The distance given is the sum of the size of the relevant half-YAC and the estimated interphase FISH distance between the BAC clone and a subtelomeric clone known to be contained within the half-YAC.
Cross-hybridization visible by FISH; see table 3 for details.
Fiber-FISH indicates a size polymorphism.