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American Journal of Human Genetics logoLink to American Journal of Human Genetics
. 1999 Nov;65(5):1486.

Errata

PMCID: PMC1288309

In the August 1998 issue of the Journal, in “Human Propionyl-CoA Carboxylase β Subunit Gene: Exon-Intron Definition and Mutation Spectrum in Spanish and Latin American Propionic Acidemia Patients” (63:360-369), by Rodríguez-Pombo et al., an error appeared in table 4. For patient PVD, the western-blot result is positive (“+c”), and, for patient PHH, the western-blot result is negative (“−”). In the Results section, the first complete sentence in the left-hand column of page 367 should read as follows: “The results indicated a total absence of immunoreactive β-PCC in all patients who were homozygous for the ins/del or c1170insT mutation and in those patients who were compound heterozygotes for the ins/del and 1298-1299insA, ins/del and R512C, or c1170insT and L519P mutations.” In the Discussion section, the last sentence in the third paragraph (p. 367) should read as follows: “The total absence of immunoreactive protein, observed in the western blot of patients who carry R512C or L519P in combination with mutations producing undetectable levels of β-PCC, such as the ins/del or c1170insT, supports the hypothesis that certain point mutations can be severe with regard to protein stability.”


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