Correction: Virology Journal (2017) 14(1):238
10.1186/s12985-017-0903-5
In this article [1], the wrong figure appeared as Fig. 3(b); the figure should have appeared as shown below.
Fig. 3.
ZEB2-AS1 was an important lncRNA that mediated HBx-induced EMT. a The level of ZEB2-AS1 was verified by a real-time PCR assay. The siRNA can effectively inhibit the level of ZEB2-AS1. b Transwell assay. Knockdown of ZEB2-AS1 inhibited the metastatic ability of HepG2 cells. c. The level of ZEB2-AS1 was verified by a real-time PCR assay. ZEB2-AS1 was up-regulated by 3.79-fold by HBx, but compromised by si-ZEB2-AS1 in HepG2-HBx. d and e The regulating effect of ZEB2-AS1 on EMT was assessed by transwell assay. HBx promoted the metastatic ability of HCC cells; however, siRNA treatment against ZEB2-AS1 rescued the phenotype in these cells. f EMT markers were detected by Western blot. HBx overexpression enhanced vimentin and ZEB2 expression, whereas it inhibited E-cadherin expression. However, knockdown ZEB2-AS1 reversed the above protein expression. *p < 0.05, **p < 0.01
Incorrect version of Fig. 3b
Correct version of Fig. 3b
Fig. 3.
ZEB2-AS1 was an important lncRNA that mediated HBx-induced EMT. a The level of ZEB2-AS1 was verified by a real-time PCR assay. The siRNA can effectively inhibit the level of ZEB2-AS1. b Transwell assay. Knockdown of ZEB2-AS1 inhibited the metastatic ability of HepG2 cells. c. The level of ZEB2-AS1 was verified by a real-time PCR assay. ZEB2-AS1 was up-regulated by 3.79-fold by HBx, but compromised by si-ZEB2-AS1 in HepG2-HBx. d and e The regulating effect of ZEB2-AS1 on EMT was assessed by transwell assay. HBx promoted the metastatic ability of HCC cells; however, siRNA treatment against ZEB2-AS1 rescued the phenotype in these cells. f EMT markers were detected by Western blot. HBx overexpression enhanced vimentin and ZEB2 expression, whereas it inhibited E-cadherin expression. However, knockdown ZEB2-AS1 reversed the above protein expression. *p < 0.05, **p < 0.01
Footnotes
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Yinji Jin and Di Wu contributed equally to this work.
Contributor Information
Xiaoming Jin, Email: Jinxm55@163.com.
Tianzhen Wang, Email: wtzpath@163.com.
Reference
- 1.Jin Yinji, Di Wu, Yang Weiwei, et al. Hepatitis B virus x protein induces epithelial-mesenchymal transition ofhepatocellular carcinoma cells by regulating long non-coding RNA. Virology Journal. 2027;14(1):56. 10.1186/s12985-017-0903-5. [DOI] [PMC free article] [PubMed] [Google Scholar]