Abstract
A thyroid function screening programme of admissions to a general psychiatric service was established. Over a 22-week period 588 patients were admitted and thyroid function tests were performed on 336, a screening rate of 57.1%. Initial investigation showed that 21.3% had a total thyroxine outside the range 75-130 nmol/l. On further investigation only 9 patients (1 thyrotoxic, 8 hypothyroid) had confirmed thyroid disease. In 7 of the 9 patients the disease had been clinically suspected. Thus the screening programme identified only 2 unsuspected cases of thyroid dysfunction and we conclude that this level of detection does not warrant a formal screening programme.
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Selected References
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- Barker D. J., Phillips D. I. Current incidence of thyrotoxicosis and past prevalence of goitre in 12 British towns. Lancet. 1984 Sep 8;2(8402):567–570. doi: 10.1016/s0140-6736(84)90776-1. [DOI] [PubMed] [Google Scholar]
- Carney M. W., Macleod S., Sheffield B. F. Thyroid function screening in psychiatric in-patients. Br J Psychiatry. 1981 Feb;138:154–156. doi: 10.1192/bjp.138.2.154. [DOI] [PubMed] [Google Scholar]
- Cohen K. L., Swigar M. E. Thyroid function screening in psychiatric patients. JAMA. 1979 Jul 20;242(3):254–257. [PubMed] [Google Scholar]
- Gray J., Hoffenberg R. Thyrotoxicosis and stress. Q J Med. 1985 Feb;54(214):153–160. [PubMed] [Google Scholar]
- Hoffenberg R. Aetiology of hyperthyroidism. I. Br Med J. 1974 Aug 17;3(5928):452–456. doi: 10.1136/bmj.3.5928.452. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Kathol R. G., Delahunt J. W., Cooke R. Urinary free cortisol levels and dexamethasone suppression testing in organic affective disorder associated with hyperthyroidism. Am J Psychiatry. 1985 Oct;142(10):1193–1195. doi: 10.1176/ajp.142.10.1193. [DOI] [PubMed] [Google Scholar]
- Levy R. P., Jensen J. B., Laus V. G., Agle D. P., Engel I. M. Serum thyroid hormone abnormalities in psychiatric disease. Metabolism. 1981 Nov;30(11):1060–1064. doi: 10.1016/0026-0495(81)90048-2. [DOI] [PubMed] [Google Scholar]
- Sheridan P., Newton K. E., Payne R. B. Interpretation of serum total thyroxine concentration in patients with abnormal thyroxine-binding proteins. Br Med J. 1978 Aug 12;2(6135):477–477. doi: 10.1136/bmj.2.6135.477. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Spratt D. I., Pont A., Miller M. B., McDougall I. R., Bayer M. F., McLaughlin W. T. Hyperthyroxinemia in patients with acute psychiatric disorders. Am J Med. 1982 Jul;73(1):41–48. doi: 10.1016/0002-9343(82)90922-6. [DOI] [PubMed] [Google Scholar]
- Tunbridge W. M., Evered D. C., Hall R., Appleton D., Brewis M., Clark F., Evans J. G., Young E., Bird T., Smith P. A. The spectrum of thyroid disease in a community: the Whickham survey. Clin Endocrinol (Oxf) 1977 Dec;7(6):481–493. doi: 10.1111/j.1365-2265.1977.tb01340.x. [DOI] [PubMed] [Google Scholar]
- Whybrow P. C., Prange A. J., Jr, Treadway C. R. Mental changes accompanying thyroid gland dysfunction. A reappraisal using objective psychological measurement. Arch Gen Psychiatry. 1969 Jan;20(1):48–63. doi: 10.1001/archpsyc.1969.01740130050004. [DOI] [PubMed] [Google Scholar]