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. 2026 Feb 17;26:38. doi: 10.1186/s12874-026-02781-9

Correction: Performance of several types of beta-binomial models in comparison to standard approaches for meta-analyses with very few studies

Moritz Felsch 1, Lars Beckmann 1, Ralf Bender 1, Oliver Kuss 2, Guido Skipka 1, Tim Mathes 3,4,
PMCID: PMC12911012  PMID: 41699496

Correction: BMC Medical Research Methodology 22, 319 (2022)

https://doi.org/10.1186/s12874-022-01779-3

Following publication of the original article [1], the authors requested to update the following errors.

Location Incorrect Correct
Abstract: Background Delete the last sentence in the Background part of the Abstract: “Therefore, we extended this model to a version that respects randomisation.”
Abstract: Results Delete the last sentence in the Results part of the Abstract: “The beta-binomial model respecting randomisation did not improve performance.”

page 3, right column,

1st paragraph

“The same formulas hold true for the number of events in the treatment arm Inline graphic with Inline graphic, Inline graphic, Inline graphic, Inline graphic, Inline graphic and Inline graphic.”, Inline graphic has to be changed to Inline graphic. “The same formulas hold true for the number of events in the treatment arm Inline graphic with Inline graphic, Inline graphic, Inline graphic, Inline graphic, Inline graphic and Inline graphic.”

page 3, right column,

3rd paragraph

Inline graphic Inline graphic
page 3, right column, 8th paragraph “In the BBST, the event probability in the control arm Inline graphic is random but the treatment effect is considered to be fixed across all studies. Thus, although the BBST is a true random effects model, from a meta-analytic point of view, it is a model with a fixed treatment effect.” “In the BBST, the event probability in the control arm Inline graphic is random and the same holds for the event probability in the treatment arm Inline graphic, so the treatment effect Inline graphic is random as well (and Inline graphic with probability 0). As the study-specific treatment effect is random, the BBST is a true random effects model, also from the standard inverse-variance meta-analytic point of view.”

page 4, left column,

2nd paragraph

“To deal with the aforementioned properties of BBST as a fixed effect model that disrespects randomisation, we implemented another BBM (BBFR) where the treatment effect …” “We implemented another BBM (BBFR) where the treatment effect…”
Inline graphic Inline graphic
page 4, left column, between 2nd and 3rd paragraph Inline graphic Inline graphic

page 4, left column,

3rd paragraph

Delete the sentence “By adding a random effect to the treatment effect, this model respects the randomisation to a study arm of a specific study.”

page 4, right column,

8th paragraph

Delete the sentences “Like the BBST, the GLMM is a random effects model. But as the treatment effect is random it is more comparable to meta-analytic REMs than the BBST.”

page 15, left column,

3rd paragraph

“The attempt to extend the BBST by a random treatment effect term for the study, due to concerns about disrespecting the randomisation, failed.” “The attempt to extend the BBST by a random treatment effect term for the study failed.”
“As BBFR uses a random effect attached to the treatment effect in addition to the random intercept, this behaviour is to be expected, because only then “enough” additional heterogeneity remains to be estimated, i.e. not all heterogeneity goes into the random intercept.” “As BBFR uses a random effect attached to the treatment effect in addition to the random intercept, this behaviour is to be expected, because only then “enough” additional heterogeneity remains to be estimated.”

page 15, right column,

2nd paragraph

Delete the sentence “One could try a BBFR with more quadrature points than 1, but this might not work because of convergence problems.”

The original article [1] has been corrected.

References

  • 1.Felsch M, Beckmann L, Bender R, et al. Performance of several types of beta-binomial models in comparison to standard approaches for meta-analyses with very few studies. BMC Med Res Methodol. 20 [DOI] [PMC free article] [PubMed] [Google Scholar]

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