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. 2026 Feb 20;12:20552076251407129. doi: 10.1177/20552076251407129

Innovative technological resources for Alzheimer's disease care management: A scoping review

Maria Almeida 1, Marta Campos Ferreira 1,2, Carla Silva Fernandes 3,4,5,
PMCID: PMC12924979  PMID: 41732182

Abstract

Objective

The aim of this scoping review was to map and describe the technological tools reported in the literature that have been designed for care management in Alzheimer's disease, with a particular focus on supporting patients living with the condition, their families, caregivers, and healthcare professionals.

Methods

The review was conducted in accordance with the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) framework. A comprehensive literature search was performed across multiple databases, including Scopus, PubMed, Web of Science, and CINAHL, focusing on studies addressing technological resources aimed at supporting the care and management of Alzheimer's disease.

Results

A total of 23 studies were included in the final analysis. The most frequently utilized technologies were mobile applications and wearable devices. The most identified functionalities included cognitive training, location tracking, task reminders, communication support, fall detection, and vital signs monitoring, often integrated into comprehensive solutions to enhance patient care and safety.

Conclusion

Overall, these technologies were designed to support both patients and caregivers. However, despite the clear benefits and innovative potential of these technologies, significant limitations remain, particularly the lack of empirical validation in real-world clinical settings and the need to ensure greater usability for older adults and individuals with cognitive impairments.

Keywords: Dementia, Alzheimer's, health app, mobile health, management

Introduction

The human brain, which contains over 60 billion nerve cells, is one of the most sophisticated biological systems. 1 However, diseases such as dementia compromise this complex biological network, disrupting cellular communication and resulting in a rapid and profound deterioration of cognitive functions.2,3 According to the World Health Organization, dementia is currently the seventh leading cause of death and one of the main causes of disability and dependency among older adults, affecting more than 55 million people worldwide, with a new case occurring somewhere in the world every 3 seconds. 4 As a result of population growth and increased life expectancy, it is estimated that by 2030, more than 75 million people will be living in this condition, with this number expected to triple by 2050.2,4,5

Dementia is a syndrome characterized by cognitive decline and loss of functional abilities, commonly caused by neurodegenerative diseases, most notably Alzheimer's disease (AD). 2 Alzheimer's disease is the most prevalent form of dementia, accounting for 60–70% of cases, and is rapidly becoming one of the most costly, lethal, and burdensome diseases of this century. It carries immeasurable physical, psychological, social, and economic impacts not only for those diagnosed but also for their caregivers, families, and society. 6 Although there is currently no cure for dementia or Alzheimer's disease, it is essential to pursue alternative approaches that focus on slowing disease progression and ensuring quality of life for both people living with the condition and those who care for them.7,8

In the healthcare context, research has shown that technology plays a crucial role by introducing new possibilities across various settings.911 Mobile health applications (apps), websites, wearable devices, and virtual and augmented reality systems are being developed to remotely monitor, guide, and support the daily lives of people with Alzheimer's and their caregivers.7,8,12,13 Technology presents numerous potential applications in the context of dementia, ranging from diagnosis and assessment to care delivery and support for ageing in place.12,13 Its use has proven effective in stimulating cognitive functions, improving communication, promoting autonomy, and strengthening social bonds for people with dementia.1316 Beyond the direct benefits for people with dementia, technologies have also been recognized as important support tools for caregivers and families.17,18 They offer features that facilitate care management and organization, safety monitoring, and even day-to-day tasks such as medication reminders, real-time location tracking, and communication with healthcare professionals.13,19,20

In this context, care management becomes a priority, as the progressive course of the disease requires structured and ongoing strategies involving patients, caregivers, and healthcare professionals.21,22 The integration of technological resources into care plans has shown great potential to support care coordination, facilitate communication among all involved, and personalize interventions according to the patient's needs.8,13

For the purposes of this review, the term ‘technology’ refers specifically to digital and electronic resources, such as mobile applications, wearable devices, web-based platforms, and sensor-based systems, that are designed to support care management.7,8,13 Given the expansion of technological resources in this field, the present article aimed to map and describe the technological tools reported in the literature that are intended for care management in Alzheimer's disease, focusing on supporting people living with the condition, their families, caregivers, and healthcare professionals.

Accordingly, this study sought to answer the following research questions:

  • → What technological resources have been developed and/or applied in the context of care management in Alzheimer's disease?

  • → What are the main functionalities and purposes of these resources in supporting individuals with AD, their caregivers, families, and healthcare professionals?

Methods

Study design

This study was conducted in accordance with the methodological guidelines of the Joanna Briggs Institute (JBI) for scoping reviews. 23 The structure of the article followed the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews) checklist, 24 ensuring transparency in the presentation of the results. The study protocol was registered on the Open Science Framework® platform (DOI 10.17605/OSF.IO/FCS3E).

Research strategy

The first step was the formulation of the research question using the Population, Concept, and Context (PCC) framework. Once the research question that best described the objectives of this review was defined, a comprehensive literature search was conducted. The final search query was developed after multiple test iterations using a wide range of different combinations. It was constructed using the PCC concepts in English and adapted to the syntax of each of the electronic databases analysed: SCOPUS, PubMed, Web of Science, and CINAHL. The most recent database search was conducted in January 2025. Regarding the Population, the terms considered included ‘Alzheimer's patient’, ‘patient with dementia’, ‘Alzheimer's caregiver’, or ‘dementia caregiver’. For the Concept, expressions such as ‘technological resource’, ‘mobile application’, ‘wearable technology’, ‘telehealth’, ‘digital health’, ‘assistive technology’, ‘website’, ‘telemedicine’, ‘online application’, ‘mobile health’, ‘digital platform’, ‘mHealth’, and ‘e-health’ were included. Concerning the Context, the terms used comprised ‘decision-making’, ‘information’, ‘management’, ‘rehabilitation’, ‘education’, ‘training’, ‘support’, ‘monitoring’, and ‘improvement’.

For example, in PubMed, the search strategy was structured as follows: (‘Alzheimer Disease’[Mesh] OR ‘dementia’[tiab] OR ‘Alzheimer's patient’[tiab] OR ‘dementia caregiver’[tiab]) AND (‘mobile application’[tiab] OR ‘wearable technology’[tiab] OR ‘telehealth’[tiab] OR ‘digital health’[tiab] OR ‘assistive technology’[tiab] OR ‘mHealth’[tiab] OR ‘e-health’[tiab]) AND (‘management’[tiab] OR ‘rehabilitation’[tiab] OR ‘support’[tiab] OR ‘monitoring’[tiab] OR ‘education’[tiab]). Similar strategies were developed for the remaining databases and were adapted as appropriate to the specific syntax and operators of each.

The results obtained from each of these databases were subsequently imported into Rayyan®, a web-based platform designed to support the development of systematic and scoping reviews. To ensure a comprehensive and accurate search, each component of the research question included relevant terms and synonyms to broaden the scope of the review.

Eligibility criteria

Only studies published in English between January 2015 and December 2024 were considered. The eligibility criteria focused on the selection of studies that directly addressed the use of technological resources applied to care management in Alzheimer's disease, according to the PCC framework (Population, Concept and Context). Eligible studies included those targeting people with Alzheimer's disease and/or their formal or informal caregivers in the context of care management. Studies based solely on basic communication technologies, such as video calls, or those not specifically designed for health management, symptom control or rehabilitation in people with Alzheimer's disease were excluded. Short conference abstracts were also excluded.

Data extraction

The results obtained from the different databases were exported to the Rayyan® 25 platform, where two researchers independently analysed all stages of the selection process. Only the articles that fully met the previously defined eligibility criteria were included in the review. The selection of studies was carried out in different phases. In the first stage, two independent reviewers (MA and CSF) screened the titles and abstracts of all records retrieved in Rayyan®. Articles that clearly did not meet the inclusion criteria were excluded at this stage. In the second stage, the same reviewers independently assessed the full texts of potentially eligible studies. Any discrepancies in the selection process were resolved through discussion and consensus with a third researcher (MCF). Data collection was supported by a database specifically designed for this purpose, allowing for a clear and structured organization of the information. This included: study identification details (author, year, country, and title), methodological characteristics (study type and objectives), information on the technology used (type and resource applied), context of application, as well as the number and profile of participants (gender, role, and involvement in the study), along with the main results and reported limitations. To ensure transparency and systematic presentation of the data, the PRISMA-ScR structure was adopted to guide the organization of information throughout the process.

Data analysis

The data were systematised and presented in a descriptive and narrative manner, using tables and figures to facilitate the reading and understanding of the main findings of the review. The extracted information was organized according to the methodological characteristics of the studies, the types of technologies identified, their functionalities, and the participant profiles, allowing the identification of patterns. The main findings were presented in supporting tables and figures, facilitating an overall understanding of the synthesized evidence.

Results

In total, 1236 records were identified, of which 248 were removed as duplicates, leaving 988 for title and abstract screening. After the exclusion of 918 records and the full-text assessment of 70 articles, 23 studies met the inclusion criteria and were incorporated into the review, as illustrated in Figure 1.1416,1820,2642

Figure 1.

Figure 1.

PRISMA – diagram flow (2020).

Table 1 presents the main data extracted from the 23 studies included, according to the items previously referenced.

Table 1.

Characteristics of the included articles

Authors Year
Country
Study design Objective Test participants Technology Study results Limitation
N Age
Gender
Disease
Patient Caregiver Health
professional
Types of technology Description Features
Kadhim et al. (2023) 26
Tunisia
Pilot Study To develop a real-time face recognition system to assist Alzheimer's patients in identifying people around them, using glasses None - - - - Wearable Camera in glasses with built-in Wi-Fi Facial Recognition
Communication Support

The prototype achieved 99.46% training accuracy and 99.48% face recognition accuracy No empirical testing;
Dependent on users consistently carrying the wearable;
Affected by device compatibility, lighting, and facial occlusions
Mohan et al. (2023) 27
India
Pilot Study Mobile App for recording and summarizing Alzheimer patients’ conversations using face recognition and NLP None - - - - Mobile App Voice capture and conversation summarization Facial Recognition
Communication Support
Speech Recognition
The app stores one-on-one conversations, improving Alzheimer's patients’ independence. No empirical testing;
Privacy concerns with conversation storage;
Usability issues in the elderly
Weerakoon et al. (2018) 28
Sri Lanka
Pilot Study To develop a cognitive training app with personalized exercises targeting motor skills, communication, memory, and written language NS NS - - Mobile App Mobile cognitive and memory support Cognitive Training
Cognitive Tracking
The system was systematically developed to support Alzheimer's patients in memory improvement Test with Patients, Healthy controls, and Suspected Alzheimer's cases.
User proficiency varies
Alhassan et al. (2017) 29
Saudi Arabia
Pilot Study App for activity reminders and assessment tools for Alzheimer's patients None - - - - Mobile APP +
Wearable
Wristband sensor and the captured data will be accessed via Application Programming Interface Cognitive Training
Cognitive Tracking
Daily Tasks Reminders
Health Signals Monitoring
The system offers activity reminders and assessment tools for caregivers. No empirical testing;
Prototype stage;
Usability issues in the elderly
Aljojo et al. (2020) 30
Saudi Arabia
Pilot Study Mobile app integrating reminders, GPS tracking, and facial recognition 354 Caregivers (N = 177):
26–40 years
81% female, 19% male
Patients (N = 177)
61 and 90 years
66% female, 34% male
- Mobile App Mobile app with location tracking, reminders, caregiver support Location Tracking
Daily Tasks Reminders
The app builds patient confidence, fosters social engagement, and supports caregivers through technologies like face recognition Facial recognition and hardware limitations; Lacks caregiver monitoring features
Vergara et al. (2015) 31
Colombia
Pilot Study Mobile health app for geolocation and safety tracking None - - - - Mobile App Internet of Things-based mobile tracking system for Alzheimer's monitoring Location Tracking
Safety Alerts
Point Of Interest Finder
Caregivers can monitor patients remotely via mobile devices. No empirical testing;
High GPS battery consumption
Acharya et al. (2016) 14
India
Pilot Study Develop a mobile app to support Alzheimer's patients by enhancing safety, providing memory aids, and assisting caregivers. NS NS - - Mobile App Conceptual mobile app guided by medical input Cognitive Training
Location Tracking
Navigation Support
Fall Detection
Safety Alerts
The app provides essential functionalities to meet users’ needs and aims to raise awareness about digital healthcare Health Professionals interviews
No empirical testing;
Re-quires internet and device sensors
Siddiq et al. (2018) 16
Pakistan
Experimental Study Mobile app combining cognitive therapy, reminders, and tracking in Urdu 20 Patients: 20 (mild to moderate stage)
Elderly (not specified in detail)
Caregivers: Participated, but exact number not specified
- Mobile App Assistive reminder app for Alzheimer care Cognitive Training
Location Tracking
Daily Tasks Reminders
Daily Tasks Tracking
CareD integrates cognitive therapies, monitoring, and reminders to reduce stress and improve dementia care. Limited to Urdu language and Android
Eichhorn et al. (2018) 32
Germany
Experimental Study Gamified activities to stimulate memory, sensory engagement, and social interaction 15 10 Alzheimer's patients
(All elderly, but exact ages are not reported)
5 caregivers
- Mobile App Cognitive support app concept for dementia care Cognitive Training
Cognitive Tracking
Gamification enhances cognitive abilities and daily functioning in Alzheimer's patients. Scalability and adaptation challenges
Siangpipop et al. (2023) 33
Thailand
Pilot Study User-friendly application for tracking and monitoring Alzheimer's patients 5 NS - - Mobile App Mobile app supporting caregivers in daily Alzheimer's care management Location Tracking
Daily Tasks Reminders
Safety Alerts
The movement tracking app was developed using design thinking to improve user experience for AD patients. Small sample size limits design assessment
Duque et al. (2016) 34
Spain
Case Study Develop a method to link smartphone movement data with Alzheimer's disease stages. 35 7 Early stage
18 Middle stage
10 late stage
- - Wearable Mobile phone accelerometer data analyzed to classify Alzheimer's stage using neural networks Cognitive Tracking
Location Tracking
Fall Detection
The smartphone-based neural network classified Alzheimer's movement patterns with 83% accuracy. Lacks integration with other sensors;
Accuracy depends on capture device quality
Byeon et al. (2019) 18
Korea
Descriptive Study Develop a machine learning model to predict depression in Alzheimer's caregivers via a mobile app. 2592 1154 males
1438 females
- - Mobile App Random forest-based depression prediction app for caregivers Depression Prediction Random Forest revealed key predictors of caregiver depression, highlighting machine learning's role Survey based data may lack personalization
Zhang et al. (2023) 35
Korea
Pilot Study App for memory exercises, reminders and routine management 70 All over 60 years old - - Mobile App Mobile app with games, reminders, tracking Cognitive Training
Location Tracking
Daily Tasks Reminders
The mobile app with a user-friendly interface improves cognitive abilities in older users, encouraging engagement in cognitive training The app was evaluated through surveys and interface simulations but not used in daily living contexts by elderly users. Limited applicability
Aljehani et al. (2018) 36
Taiwan
Pilot Study Develop an IoT system using Apple Watch to monitor and support Alzheimer's patients 36 NS - - - Mobile APP +
Wearable
Apple Smartwatch connected with IOS app Location Tracking
Daily Tasks Reminders
Health Signals Monitoring
Educational Tools
Safety Alerts
iCare integrates IoT with Apple smartwatches to enhance Alzheimer's patient safety and task management. Limited to Apple devices;
Internet required for data sync
Biswas et al. (2021) 15
Bangladesh
Pilot Study Design an indoor navigation system using BLE beacons and Wi-Fi for Alzheimer's patients. None - - - - Mobile APP

Combination of wall-mounted wireless sensors, a mobile app and WiFi/Bluetooth beacons Location Tracking
Navigation Support
Real-time remote monitoring system supports families and clinicians. No testing; inaccurate RSS, signal interference, security risks, and user interaction required.
Rashmi et al. (2023) 37
India
Pilot Study Wearable device to monitor Alzheimer's patients’ vitals, fall detection, and location tracking 13 13 healthy volunteers Aged 22-33 - - Wearable Wearable device with biometrics, fall detection, GPS tracking Location Tracking
Fall Detection
Health Signals Monitoring
The wearable device monitors Alzheimer's patients’ biometrics and GPS location, achieving 93% fall detection sensitivity and 95% specificity No empirical testing;
Dependent on Wi-Fi;
Requires sensor calibration;
Limited battery life
Duarte et al. (2023) 38
Portugal
Pilot Study Mobile app to monitor and manage dietary plans for Alzheimer's patients, providing real-time feedback to nutritionists 20 60–70 years (mean 64.8)
14 female, 6 male
- - Mobile App Mobile app for food tracking and caregiver support Daily Tasks Tracking The mobile app simplifies meal tracking and nutritional monitoring. Does not address mobility or communication aspects ofcare
Amaro et al. (2024) 39
Italy
Pilot Study Dynamic and personalized serious game to enhance spatial and autobiographical memory in Alzheimer's patients. None - - - - Mobile APP +
Website
Personalized serious game for memory rehabilitation Cognitive Training
Cognitive Tracking
MoM is a cognitive rehabilitation tool designed to slow memory decline and improve emotional well-being. No empirical testing
Intended for Alzheimer's patients (early to moderate stage)
Francis et al. (2024) 40
USA
Pilot Study AI-driven mobile app supporting Alzheimer's caregivers by identifying patient personality and guiding daily care interactions 16 Females
Aged
20-48
- - Mobile App Affective AI mobile app simulating identity-based social interactions. Communication Support VIPCare uses AI to support emotionally intelligent dementia care, aiming to improve well-being and reduce caregiver stress. Residents were not directly assessed due to cognitive impairment; profiles relied on caregiver reports and were impacted by COVID-19.
Fardoun et al. (2017) 20
Saudi Arabia
Pilot Study A mobile-cloud-based architecture using face recognition for Alzheimer's patients to identify and recall familiar people 41 23 males
18 females
Aged 55-72
- - Mobile APP +
Wearable
Real-world scenario with smartwatch and mobile app for face recognition Facial Recognition
Communication Support
The cloud-based system helps Alzheimer's patients recognize familiar people, but usability issues remain. Usability issues in the elderly;
Dependent on network and hardware limitations
Chaudhry et al. (2021) 41
USA
Pilot Study Mobile app designed to help dementia patients and caregivers manage daily tasks, cognitive stimulation, and communication 5 - - - Mobile App Tablet app for memory and caregiver interaction support Cognitive Training
Daily Tasks Reminders
RefineMind supports dementia care with memory aids and communication tools. Usability issues in the elderly;
Requires internet;
Limited clinical validation
Lobo et al. (2023) 42
India
Pilot Study Wearable IoT device providing GPS tracking, health monitoring, and reminders for Alzheimer's patients None - - - - Mobile APP +
Wearable
Real-time location tracking (via GPS), health monitoring (heartbeat, BP), food/medication reminders Location Tracking
Daily Tasks Reminders
Health Signals Monitoring
Safety Alerts
Enhances patient safety with location tracking, health monitoring, and reminders. No empirical testing;
Location updates every 30 min; Dependent on internet for real time tracking
Jimenez et al. (2024) 19
Peru
Experimental Study Energy-efficient wearable shoe device for geolocation using piezoelectric energy harvesting 1 NS - - - Mobile APP +
Wearable
Shoe developed with a LoRa technology Location Tracking
Safety Alerts
The geolocation system successfully tracks Alzheimer's patients in real time. Tested by one user; not with Alzheimer's patients. Limited range and battery issues

APP + Wearable – mobile application integrated with a wearable device; APP + Website – mobile application integrated with a web platform; Mobile APP – mobile application; BP – blood pressure; GPS – Global Positioning System; IoT – Internet of Things; LoRa – long range (low−power, wide-area wireless communication protocol); BLE – Bluetooth Low Energy; RSS – received signal strength; AD – Alzheimer's disease; iCare – integrated care application; NLP – Natural Language Processing; AI – artificial intelligence; MoM – Mosaic of Memory (serious game); CareD – Cognitive Assistance and Reminder Device; IOS – Apple Operating System; N – number of participants; NS – not specified; √ – present/included

Characteristics of the included studies

A total of 23 articles published between 2015 and 2024 were included. Most studies were published in 2023.26,27,33,35,37,38,42 Although a sharper increase in publications might have been expected following the 2020 pandemic, the data indicate that interest in technology-based solutions for Alzheimer's disease had already been growing, reflecting the advancement of digital innovation.43,44 In terms of methodological design, most studies were exploratory or descriptive in nature, with a predominance of pilot studies, commonly used to validate prototypes or assess usability during early stages of technological development.

Characteristics of participants

Regarding participants, the 23 included studies involved a total of 3405 individuals. The number of participants per study varied widely, ranging from 1 19 to 2592. 18 However, seven studies did not conduct user testing (n = 7),15,26,27,29,31,39,42 limiting their findings to prototype descriptions without validation by the target population. One additional study 14 did not specify whether user testing was performed (NS).

Participant profiles also varied considerably, reflecting the diverse objectives of the technological solutions analyzed. Three main recipient groups were identified: patients (n = 7),16,20,28,30,32,34,35 caregivers (n = 8),16,18,30,32,33,38,40,41 most of whom were family members, and healthcare professionals (n = 3).14,19,37

Regarding demographic information, not all studies have reported complete data on age, gender or participant profiles, which limits the possibility of systematic comparisons. Where such information was available, most patients were older adults aged over 60 years, with some studies reporting mean ages between 64 and 70 years. Several studies also highlighted a predominance of female participants, both among patients and caregivers.

Characteristics of technological resources

The analysis of the studies included revealed a wide range of technological solutions. The most used technology was the mobile application, reported in most studies (n = 20).1420,2733,35,36,3842 (Figure 2)

Figure 2.

Figure 2.

Distribution of studies according to the type of technology used.

These applications were developed for various purposes, including cognitive training, daily task reminders, real-time location tracking, caregiver communication support, and health monitoring. In addition, integration with wearable devices was identified in eight studies,19,20,26,29,34,36,37,42 involving smartwatches, wristbands, sensorized vests, and sensor-equipped shoes. Although less frequent, one study included a complementary web-based platform integrated with a mobile app, 39 consisting of a personalized serious game for memory training. This illustrates the potential of hybrid approaches that combine mobile and online digital technologies for therapeutic purposes.

The most frequent functionalities found across the technological solutions included cognitive training and screening,14,16,182730,32,35,3841 GPS or Bluetooth beacon-based location tracking,1416,19,20,28,30,31,3437,42 task and medication reminders, 16 2931,33,35,36,41,42 fall detection,14,34,37 communication support,20,26,27,40 and vital sign monitoring.29,36,37,42

Discussion

This scoping review enabled the mapping and characterization of technological resources developed within the context of care management in Alzheimer's Disease (AD). The technological tools identified were targeted toward three main user profiles: patients diagnosed with Alzheimer's disease,19,20,28,30,313439 informal or family caregivers,18,30,32,33,38,40,41 and, to a lesser extent, healthcare professionals.14,19,37

Patients were involved in several studies, either as direct end-users or as prototype testers, contributing to the evaluation of usability and potential clinical benefits.20,28,30,31,34,35 The inclusion of the lived experience of people with the disease provides unique insights into how digital technologies should be developed.28,30 Regarding caregivers, their involvement was often limited to usability testing rather than co-design,18,30,32,33,38 despite their perspectives being crucial to ensuring adherence, acceptability, and the integration of these tools into the routines of patients and families. Healthcare professionals were included in only three studies,14,19,37 and even then, their participation was mainly restricted to conceptual design or validation stages. This limited involvement highlights a significant gap, since professionals are also key actors in clinical implementation and can bridge the divide between technological innovation and clinical practice. Overall, these findings suggest that future research should aim for a more balanced and active involvement of all three groups.

Regarding the temporal distribution of publications, most studies were published in 2023,26,27,33,35,37,38,42 reflecting a growing interest from the scientific community in this field. Nevertheless, the growth of evidence has been gradual and irregular over the past decade, with no continuous progression of publications since 2015.

The expectation of a sharper increase in publications after 2020 is consistent with the accelerated adoption of digital technologies during the COVID-19 pandemic.43,44 However, despite this global trend, the number of studies addressing the management of Alzheimer's disease through digital solutions has remained limited. This suggests that although innovations in digital health have expanded rapidly, their application in this context may have encountered additional barriers, including ethical considerations, usability challenges, and the complexity of adapting technologies to populations with cognitive impairment.

The 23 included studies revealed a growing diversity of digital solutions, with an emphasis on mobile applications, reflecting the advancement of technological innovation and findings consistent with other studies in different populations.11,45,46 Among the technological resources identified, mobile applications were the most frequently reported technologies.1416,1820,2733,35,36,3842 These applications varied in terms of structure and functionality and were designed for mobile devices such as smartphones and tablets. Some applications were standalone tools, while others were integrated with external sensors or cloud-based platforms.20,27,29,36,42

Integration with wearable devices was reported in eight studies,19,20,26,29,34,36,37,42 taking various forms such as smartwatches,20,36 wristbands, 29 sensorized vests, 37 and GPS-enabled footwear. 19 Communication between wearable devices and mobile applications occurred, in most cases, through Bluetooth or Wi-Fi connectivity,20,26,29,42 enabling real-time transmission of data such as location, movement patterns, vital signs, and automated alerts.19,36,37,42

Wearable devices represent a promising strategy for managing various conditions, although their acceptance still depends on overcoming barriers related to comfort, usability, and emotional impact on patients.47,48

This scoping review identified a range of functionalities integrated into technological resources, often combined to optimize support for both the patient and the family caregiver. Cognitive training and screening were one of the functionalities identified,14,18,27,28,30,353840 particularly in mobile applications offering personalized, gamified, and adaptive exercises aimed at stimulating memory, attention, language, and other cognitive functions. These tools were used for both cognitive rehabilitation and early screening of cognitive decline.

Location tracking was another widely reported functionality,1416,19,20,28,30,31,3436,42 primarily implemented through GPS and Bluetooth beacons, enabling real-time geolocation and the use of geofencing to alert caregivers when patients move beyond predefined safe zones. Devices such as smartwatches, sensor-embedded shoes, and integrated mobile systems enhanced safety and continuous monitoring.

Task and medication reminders were also a recurring feature in the analyzed articles, 16 2931,35,36 aiming to support treatment adherence and the organization of daily routines.

Fall detection14,34,37,42 was implemented using inertial sensors embedded in wearable devices, capable of identifying abrupt movement patterns and automatically issuing alerts.

Regarding communication support,27,30,40 this functionality involved technologies such as facial recognition, voice command systems, and artificial intelligence. These solutions aimed to facilitate social interaction and assist in the recognition of family members and caregivers.30,40

The functionality of vital signs monitoring29,36,37,42 was predominantly associated with the use of wearable devices such as smartwatches and wristbands, allowing for continuous tracking of physiological parameters such as heart rate, sleep quality, and blood pressure. The availability of these real-time data provides critical information for clinical follow-up and supports decision-making by caregivers and healthcare professionals.29,36

The studies reviewed highlight a growing trend in the adoption of integrated digital solutions, with a strong emphasis on mobile applications and wearable devices19,20,26,29,34,36,37,42 that incorporate multiple functionalities aimed at optimizing the care of patients with Alzheimer's disease and offering comprehensive support to caregivers.

Although the reviewed articles provide valuable insights into technological solutions for Alzheimer's disease care, several aspects highlight the existing challenges and gaps in this field. An important concern is that many of the identified tools did not specify whether their design considered suitability for people with specific needs, low digital literacy, or older adults.14,26,29,31,39,42 Aspects such as simplified interfaces, the use of larger fonts, or cultural adaptation of content were not described, which may limit the inclusiveness and applicability of these technological solutions in real-world settings.14,26,29,42

Some solutions also rely heavily on continuous device usage,19,20,36,37,42 which may compromise their effectiveness, particularly given the known barriers to technology adherence among older adults. Technical challenges are also frequently reported. The accuracy of facial recognition, voice commands, and location tracking can be adversely affected by factors such as lighting conditions, facial occlusion, sensor quality, and signal interference from Wi-Fi, BLE, or LoRa networks.15,19,20,30,31,34,36,40 Certain systems exhibit high battery consumption and require constant internet connectivity, limiting their usability in specific environments.19,29,36,42 For example, navigation systems often do not account for the dynamic nature of real-world settings, variability in GPS accuracy, or challenges posed by dense urban areas and locations with limited connectivity. Ethical and privacy issues are also of concern, particularly when sensitive data such as voice recordings or location history are stored and processed,15,19,20,30,31,34,36,40 as highlighted in recent literature addressing surveillance, consent, and data governance.49,50

Limitations

This study presents several limitations that should be acknowledged when interpreting its findings. Most studies remain at the prototype stage, were conducted with small and homogeneous samples, or were not tested in real patients or clinical environments. These factors limit the empirical validation of their applicability and effectiveness. The lack of robust clinical trials and real-world validation underscores the need for future research to ensure the feasibility and effectiveness of these technologies in supporting patients living with Alzheimer's disease. In addition, this scoping review is subject to methodological limitations, including the potential exclusion of relevant sources due to the restriction to studies published in English, as well as the temporal cut-off from 2015 onwards, which may have affected the comprehensiveness and depth of the findings presented.

Conclusion

This scoping review enabled the mapping and characterization of technological resources developed for care management in Alzheimer's disease, highlighting an expanding landscape of digital solutions aimed at supporting patients diagnosed with the condition, their caregivers, and healthcare professionals. Emphasis was noted on the use of mobile applications and wearable devices. Although these innovative developments are promising, several limitations were identified. Many existing solutions lack sufficient clinical validation. Technical barriers, ethical and privacy implications, and notably, the difficulty older adults, particularly those with cognitive impairment in adopting and trusting smartphones and other technological systems, remain significant challenges in this field.

Therefore, further research is required to overcome technical limitations, validate user effectiveness across diverse populations, and address ethical considerations. The insights gathered in this review not only underscore the potential of digital interventions but also illuminate critical gaps that future research must address to fully realize their benefits in both clinical and everyday care settings.

Footnotes

ORCID iDs: Marta Campos Ferreira https://orcid.org/0000-0001-9505-5730

Carla Silva Fernandes https://orcid.org/0000-0001-7251-5829

Contributorship: MA: conceptualization, data curation, resources, software; formal analysis, investigation, methodology, project administration, validation, and writing – original draft. MCF: conceptualization, formal analysis, supervision, investigation, methodology, and writing – review and editing. CSF: conceptualization, formal analysis, supervision, investigation, methodology, writing – original draft, and writing – review and editing.

Funding: The authors received no financial support for the research, authorship, and/or publication of this article.

The authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

References

  • 1.Goriely A. Eighty-six billion and counting: do we know the number of neurons in the human brain? Brain 2024; 148: 689–691. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 2.Jönsson L, Tate A, Frisell O, et al. The costs of dementia in Europe: an updated review and meta-analysis. PharmacoEconomics 2023; 41: 59–75 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 3.Ditton A, Alodan H, Fox C, et al. Exploring the effectiveness and experiences of people living with dementia interacting with digital interventions: a mixed methods systematic review. Dementia (London) 2025; 24: 506–551. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 4.World Health Organization. Dementia [Internet]. Geneva: WHO, 2025.: https://www.who.int/news-room/fact-sheets/detail/dementia [Google Scholar]
  • 5.World Health Organization. Global status report on the public health response to dementia. Geneva: World Health Organization, 2021. https://apps.who.int/iris . [Google Scholar]
  • 6.Sun BL, Li WW, Zhu C, et al. Clinical research on Alzheimer’s disease: progress and perspectives. Neurosci Bull 2018; 34: 1111–1118. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 7.Rashid NSA, Rahman NA, Kamarudin LM, et al. Supporting caregivers of people with dementia: insights from demensia KITA mobile application online content development. Sci Rep 2024; 14: 19302. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 8.Wang Q. Computer internet of things-based intelligent medical system to be applied in home care of Senile dementia patients. Wirel Commun Mob Comput 2022; 2022: 1374835. [Google Scholar]
  • 9.Fernandes C, Magalhães B, Santos C, et al. IGestsaúde: a mobile application for the self-management of symptoms associated with chemotherapy treatment: development protocol. Nurs Pract Today 2020; 8: 146–154. [Google Scholar]
  • 10.Ferreira J, Ferreira M, Fernandes CS, et al. Digitisation of patient preferences in palliative care: mobile app prototype. BMJ Support Palliat Care 2023: e558–e561. doi: 10.1136/spcare-2023-004516. Epub ahead of print. [DOI] [PubMed] [Google Scholar]
  • 11.Gonçalves HIT, Ferreira MC, Campos MJ, et al. Using digital technology to promote patient participation in the rehabilitation process in hip replacement: a scoping review. Comput Inform Nurs 2024; 42: 737–745. [DOI] [PubMed] [Google Scholar]
  • 12.Valladares-Rodríguez S, Muñoz-Rodríguez JR, Álvarez-Suárez A, et al. Evaluation of the predictive ability and user acceptance of panoramix 2.0, an AI-based e-health tool for the detection of cognitive impairment. Electronics (Basel) 2022; 11: 3424. [Google Scholar]
  • 13.Astell AJ, Bouranis N, Hoey J, et al. Technology and dementia: the future is now. Dement Geriatr Cogn Disord 2019; 47: 131–139. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 14.Acharya MH, Bhatt A, Bhatt A, et al. Android application for dementia patient. In: In: 2016 international conference on inventive computation technologies (ICICT). coimbatore. India: IEEE, 2016, pp.1–4. [Google Scholar]
  • 15.Biswas M, Rahman M, Islam M, et al. Indoor navigation support system for patients with neurodegenerative diseases. In: Mahmud M, Kaiser MS, Vassanelli S, Zhong N. (eds) Brain informatics. Lecture notes in computer science. 12960. Cham: Springer International Publishing, 2021, pp.411–422. [Google Scholar]
  • 16.Siddiq K, Ali T, Nawaz R, et al. Cared: non-pharmacological assistance for dementia patients. EAI Endors Trans Pervasive Health Technol 2018; 4: e3. [Google Scholar]
  • 17.McLaren JE, McCloskey R, Courneya CA, et al. Development and evaluation of a clinician-vetted dementia caregiver resources website: mixed methods approach. JMIR Form Res 2024; 8: e54168. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 18.Byeon H. Developing a random forest classifier for predicting the depression and managing the health of caregivers supporting patients with Alzheimer’s disease. Technol Health Care 2019; 27: 531–544. [DOI] [PubMed] [Google Scholar]
  • 19.Jimenez SLR, Aranda GJ, Montesinos DH, et al. Wearable with integrated piezoelectric energy harvester for geolocation of people with Alzheimer’s. Int J Electr Comput Eng 2024; 14: 497–508. [Google Scholar]
  • 20.Fardoun HM, Mashat AA, Castillo JR. Recognition of familiar people with a mobile cloud architecture for Alzheimer patients. Disabil Rehabil 2017; 39: 398–402. [DOI] [PubMed] [Google Scholar]
  • 21.Sun BL, Li WW, Zhu C, et al. Clinical research on Alzheimer’s disease: progress and perspectives. Neurosci Bull 2018; 34: 1111–1118. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 22.Safiri S, Ghaffari Jolfayi A, Fazlollahi A, et al. Alzheimer’s disease: a comprehensive review of epidemiology, risk factors, symptoms diagnosis, management, caregiving, advanced treatments and associated challenges. Front Med (Lausanne) 2024; 11: 1474043. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 23.Peters MDJ, Godfrey C, McInerney P, et al. Scoping reviews. In: Aromataris E, Lockwood C, Porritt K, Pilla B, Jordan Z. (eds) JBI Manual for evidence synthesis. Adelaide: JBI, 2024, pp.1–xx. [Google Scholar]
  • 24.Tricco AC, Lillie E, Zarin W, et al. PRISMA Extension for scoping reviews (PRISMA-ScR): checklist and explanation. Ann Intern Med 2018 Oct 2; 169: 467–473. [DOI] [PubMed] [Google Scholar]
  • 25.Ouzzani M, Hammady H, Fedorowicz Z, et al. Rayyan—a web and mobile app for systematic reviews. Syst Rev 2016; 5: 210. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 26.Kadhim TA, Salim MY, Abid MR, et al. A face recognition application for Alzheimer’s patients using ESP32-CAM and raspberry pi. J Real-Time Image Process 2023; 20: 100. https://doi.org/10.1007/s11554-023-01357-w [Google Scholar]
  • 27.Mohan HS, Acharya S, Suhas KM, et al. A novel approach to record and narrate the summary of conversation for Alzheimer patient. In: 2023 international conference for advancement in technology (ICONAT), Goa, India, 24–26 January 2023, pp.1–6. IEEE. [Google Scholar]
  • 28.Weerakoon DSD, Kahandawaarachchi KADCP, Dissanayake JDSY, et al. AD Mini: memory improvement tool for Alzheimer’s patients. In: Proceedings of the 13th international conference on computer science & education (ICCSE 2018), Colombo, Sri Lanka, 8–11 August 2018, pp.556–561. IEEE. [Google Scholar]
  • 29.Alhassan S, Alrajhi W, Alhassan A, et al. ADMemento: a prototype of activity reminder and assessment tools for patients with Alzheimer’s disease. In: Zaphiris P, Ioannou A. (eds) Learning and collaboration technologies. Novel learning ecosystems. Cham: Springer, 2017, pp.23–33. [Google Scholar]
  • 30.Aljojo N, Al-Otaibi R, Alharbi B, et al. Alzheimer assistant: a mobile application using machine learning. Rev Rom Inform Autom 2020; 30: 7–26. [Google Scholar]
  • 31.Vergara JA, Ramírez YM, Camargo JE. A pervasive and ubiquitous mobile health application for tracking people with disabilities. In: In: 2015 10th computing Colombian conference (10CCC); 2015. Bogota, Colombia: IEEE, 2015, pp.206–213. [Google Scholar]
  • 32.Eichhorn C, Plecher DA, Klinker G, et al. Innovative game concepts for Alzheimer patients. In: Zhou J, Salvendy G. (eds) Human aspects of IT for the aged population. Applications in health, assistance, and entertainment (ITAP 2018). Cham: Springer, 2018, pp.526–545. [Google Scholar]
  • 33.Siangpipop S, Yordkaew S, Klaynak K. Designing a mobile app for managing Alzheimer's disease: a user-centered. In: 2023 Joint international conference on digital arts, Media and technology with ECTI northern section conference on electrical, electronics, computer and telecommunications engineering. IEEE, 2023, pp.37–42. [Google Scholar]
  • 34.Duque R, Nieto-Reyes A, Martínez C, et al. Detecting human movement patterns through data provided by accelerometers: a case study regarding Alzheimer’s disease. In: García C, Caballero-Gil P, Burmester M, Quesada-Arencibia A, editors. Ubiquitous computing and ambient intelligence. UCAmI 2016 . Cham: Springer; 2016. p.53–64. [Google Scholar]
  • 35.Zhang S, Wang S. Digital treatment: base on the mobile interface for memory improvement of elderly. In: Proceedings of the 2023 4th international symposium on artificial intelligence for medicine science (ISAIMS 2023); 2023 Oct 20–22; Chengdu, China. New York: ACM; 2023. p.1–4. [Google Scholar]
  • 36.Aljehani SS, Alhazmi RA, Aloufi SS, et al. iCare: applying IoT technology for monitoring Alzheimer's patients. In: 2018 conference on applied internet and information technology (CAIS), IEEE, 2018, pp.1–6. doi: 10.1109/CAIS.2018.8442010 [Google Scholar]
  • 37.Rashmi GP, Sreenivasulu KN, Prathima N, et al. Smart wearable memory band system for Alzheimer’s patients. In: 2023 international conference on smart systems for applications in electrical sciences (ICSSES), IEEE, 2023, pp.1–5. doi: 10.1109/ICSSES58299.2023.10200826 [Google Scholar]
  • 38.Duarte RP, Cunha CAS, Alves VNN. Mobile application for real-time food plan management for Alzheimer patients through design-based research. Future Internet 2023; 15: 168. [Google Scholar]
  • 39.Amaro I, Della Greca A, Tucci C, et al. Mosaic of Memory: a serious game to improve spatial and autobiographical memory in Alzheimer’s patients. In: INI-DH 2024: Workshop on innovative interfaces in digital healthcare, in conjunction with AVI 2024, Arenzano, Genoa, Italy, 3–7 June 2024, CEUR Workshop Proceedings, 2024, pp.1–6. https://ceur-ws.org/Vol-3715/paper7.pdf. [Google Scholar]
  • 40.Francis L, Ghafurian M. Preserving the self with artificial intelligence using VIPCare—a virtual interaction program for dementia caregivers. Front Sociol 2024 Feb 5; 9: 1331315. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 41.Chaudhry BM, Smith J. RefineMind: a mobile app for people with dementia and their caregivers. In: Holzinger A, Ziefle M, Röcker C. (eds) Pervasive health: Pervasive computing technologies for healthcare. Cham: Springer, 2021, pp.16–21. [Google Scholar]
  • 42.Lobo MA, Sowmya K, Mimani H, et al. TagAlong: an assistive device for Alzheimer patients. In: 2023 International conference on intelligent and innovative technologies in computing, electrical and electronics (IITCEE), IEEE, 2023, pp.342–347. [Google Scholar]
  • 43.Ohannessian R, Duong TA, Odone A. Global telemedicine implementation and integration within health systems to fight the COVID-19 pandemic: a call to action. JMIR Public Health Surveill 2020; 6: e18810. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 44.Smith AC, Thomas E, Snoswell CL, et al. Telehealth for global emergencies: implications for coronavirus disease 2019 (COVID-19). J Telemed Telecare 2020; 26: 309–313. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 45.Martins AR, Ferreira MC, Fernandes CS. Emerging technologies for supporting patients during hemodialysis: a scoping review. Int J Med Inform [Internet] 2024; 181: 105664. [DOI] [PubMed] [Google Scholar]
  • 46.Amarelo A, Mota M, Amarelo B, et al. Technological resources for physical rehabilitation in cancer patients undergoing chemotherapy: a scoping review. Cancers (Basel) 2024; 16: 3949. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 47.Ma Y, Zhang Y, Li R, et al. The experience and perception of wearable devices in Parkinson’s disease patients: a systematic review and meta-synthesis of qualitative studies. J Neurol 2025; 272: 350. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 48.Mohrag M, Mojiri ME, Hakami MS, et al. The impact of wearable technologies on blood pressure control in hypertensive patients: a systematic review and meta-analysis. Cureus 2024; 16: e71220. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 49.Köhler S, Perry J, Biernetzky OA, et al. Ethics, design, and implementation criteria of digital assistive technologies for people with dementia from a multiple stakeholder perspective: a qualitative study. BMC Med Ethics 2024; 25: 84. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 50.Wangmo T, Lipps M, Kressig RW, et al. Ethical concerns with the use of intelligent assistive technology: findings from a qualitative study with professional stakeholders. BMC Med Ethics 2019; 20: 98. [DOI] [PMC free article] [PubMed] [Google Scholar]

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