Lin Zheng
Lin Zheng
1Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China
2The Research Institute for Joint Diseases, Shanghai Academy of Traditional Chinese Medicine, Shanghai, China
Writing – original draft
1,2,†,
Xinyu A
Xinyu A
1Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China
2The Research Institute for Joint Diseases, Shanghai Academy of Traditional Chinese Medicine, Shanghai, China
Software, Writing – original draft
1,2,†,
Shiyu Ma
Shiyu Ma
3The Department of Pharmacy Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China
Writing – original draft
3,†,
Bo Xu
Bo Xu
1Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China
Writing – original draft, Data curation
1,
Zheng Xiang
Zheng Xiang
1Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China
2The Research Institute for Joint Diseases, Shanghai Academy of Traditional Chinese Medicine, Shanghai, China
Writing – original draft
1,2,
Boran Cao
Boran Cao
1Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China
Writing – review & editing
1,
Jun Shen
Jun Shen
1Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China
Writing – review & editing
1,
Xirui Xu
Xirui Xu
1Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China
Writing – review & editing
1,
Yiwei Cheng
Yiwei Cheng
1Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China
2The Research Institute for Joint Diseases, Shanghai Academy of Traditional Chinese Medicine, Shanghai, China
Writing – original draft
1,2,
Lei Ran
Lei Ran
1Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China
2The Research Institute for Joint Diseases, Shanghai Academy of Traditional Chinese Medicine, Shanghai, China
Writing – original draft
1,2,
Qi Shi
Qi Shi
1Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China
Writing – original draft
1,
Yanqin Bian
Yanqin Bian
1Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China
2The Research Institute for Joint Diseases, Shanghai Academy of Traditional Chinese Medicine, Shanghai, China
Writing – original draft
1,2,*,
Lianbo Xiao
Lianbo Xiao
1Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China
2The Research Institute for Joint Diseases, Shanghai Academy of Traditional Chinese Medicine, Shanghai, China
Writing – review & editing
1,2,*
1Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China
2The Research Institute for Joint Diseases, Shanghai Academy of Traditional Chinese Medicine, Shanghai, China
3The Department of Pharmacy Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China
*Correspondence: Lianbo Xiao, xiao_lianbo@163.com; Yanqin Bian, xiaobian504@126.com
†These authors have contributed equally to this work
Roles
Lin Zheng: Writing – original draft
Xinyu A: Software, Writing – original draft
Shiyu Ma: Writing – original draft
Bo Xu: Writing – original draft, Data curation
Zheng Xiang: Writing – original draft
Boran Cao: Writing – review & editing
Jun Shen: Writing – review & editing
Xirui Xu: Writing – review & editing
Yiwei Cheng: Writing – original draft
Lei Ran: Writing – original draft
Qi Shi: Writing – original draft
Yanqin Bian: Writing – original draft
Lianbo Xiao: Writing – review & editing
Received 2026 Feb 2; Accepted 2026 Feb 4; Collection date 2026.
Keywords: lactate metabolism, rheumatoid arthritis, immune homeostasis, precision therapy, lactylation, metabolic reprogramming
Copyright © 2026 Zheng, A, Ma, Xu, Xiang, Cao, Shen, Xu, Cheng, Ran, Shi, Bian and Xiao.
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
