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. 1991 Sep;84(9):550–553. doi: 10.1177/014107689108400916

Children's psychological health status--the impact of liver transplantation: a review.

R Bradford 1
PMCID: PMC1293419  PMID: 1719199

Abstract

Medical audit needs to encompass physical, psychological and social aspects to patient functioning. The aim of this paper is to review the psychosocial impact of liver transplantation on children and their families. Evidence suggests that end stage liver diseases are associated with developmental delays. Emotional and behavioural problems are common and have been found to relate to the child's developmental status, physical appearance as well as family functioning. Post transplant, children and families often experience an exacerbation of preexisting emotional problems. One year post transplant, children typically show continuing developmental delays. Longer term assessments of quality of life suggest that children may experience fewer hospital contacts and that over time psychological difficulties reduce. Many families continue to experience problems in normalizing their interactions within and outside the family. The findings demonstrate the importance of including psychosocial outcomes in auditing the efficacy of medical interventions.

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Selected References

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  1. Alagille D., Odièvre M., Gautier M., Dommergues J. P. Hepatic ductular hypoplasia associated with characteristic facies, vertebral malformations, retarded physical, mental, and sexual development, and cardiac murmur. J Pediatr. 1975 Jan;86(1):63–71. doi: 10.1016/s0022-3476(75)80706-2. [DOI] [PubMed] [Google Scholar]
  2. Andrews W., Fyock B., Gray S., Coln D., Hendrickse W., Siegel J., Belknap B., Hogge A., Benser M., Kennard B. Pediatric liver transplantation: the Dallas experience. Transplant Proc. 1987 Aug;19(4):3267–3276. [PubMed] [Google Scholar]
  3. Boutsen C., Gilbert S. Cost of liver transplantation: financing and social aspects. Transplant Proc. 1987 Aug;19(4):3363–3366. [PubMed] [Google Scholar]
  4. Bradford R. Short communication: the importance of psychosocial factors in understanding child distress during routine X-ray procedures. J Child Psychol Psychiatry. 1990 Sep;31(6):973–982. doi: 10.1111/j.1469-7610.1990.tb00838.x. [DOI] [PubMed] [Google Scholar]
  5. Bradford R., Tomlinson L. Psychological guidelines in the management of paediatric organ transplantation. Arch Dis Child. 1990 Sep;65(9):1000–1003. doi: 10.1136/adc.65.9.1000. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Breslau N., Weitzman M., Messenger K. Psychologic functioning of siblings of disabled children. Pediatrics. 1981 Mar;67(3):344–353. [PubMed] [Google Scholar]
  7. Burgess D. B., Martin H. P., Lilly J. R. The developmental status of children undergoing the Kasai procedure for biliary atresia. Pediatrics. 1982 Oct;70(4):624–629. [PubMed] [Google Scholar]
  8. Carr A., McDonnell D. J. Wilson's disease in an adolescent displaying an adjustment reaction to a series of life stressors: a case study. J Child Psychol Psychiatry. 1986 Sep;27(5):697–700. doi: 10.1111/j.1469-7610.1986.tb00194.x. [DOI] [PubMed] [Google Scholar]
  9. Colonna J. O., 2nd, Brems J. J., Hiatt J. R., Millis J. M., Ament M. E., Baldrich-Quinones W. J., Berquist W. E., Besbris D., Brill J. E., Goldstein L. I. The quality of survival after liver transplantation. Transplant Proc. 1988 Feb;20(1 Suppl 1):594–597. [PubMed] [Google Scholar]
  10. Davis L. J., Jr, Goldstein N. P. Psychologic investigation of Wilson's disease. Mayo Clin Proc. 1974 Jun;49(6):409–411. [PubMed] [Google Scholar]
  11. Gold L. M., Kirkpatrick B. S., Fricker F. J., Zitelli B. J. Psychosocial issues in pediatric organ transplantation: the parents' perspective. Pediatrics. 1986 May;77(5):738–744. [PubMed] [Google Scholar]
  12. House R., Dubovsky S. L., Penn I. Psychiatric aspects of hepatic transplantation. Transplantation. 1983 Aug;36(2):146–150. doi: 10.1097/00007890-198308000-00007. [DOI] [PubMed] [Google Scholar]
  13. KNEHR C. A., BEARN A. G. Psychological impairment in Wilson's disease. J Nerv Ment Dis. 1956 Sep;124(3):251–255. doi: 10.1097/00005053-195609000-00005. [DOI] [PubMed] [Google Scholar]
  14. Krener P. G. Psychiatric liaison to liver transplant recipients. Clin Pediatr (Phila) 1987 Feb;26(2):93–97. doi: 10.1177/000992288702600207. [DOI] [PubMed] [Google Scholar]
  15. Lask B., Matthew D. Childhood asthma. A controlled trial of family psychotherapy. Arch Dis Child. 1979 Feb;54(2):116–119. doi: 10.1136/adc.54.2.116. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Paradis K. J., Freese D. K., Sharp H. L. A pediatric perspective on liver transplantation. Pediatr Clin North Am. 1988 Apr;35(2):409–433. doi: 10.1016/s0031-3955(16)36437-9. [DOI] [PubMed] [Google Scholar]
  17. Penn I., Bunch D., Olenik D., Abouna G. Psychiatric experience with patients receiving renal nad hepatic transplants. Semin Psychiatry. 1971 Feb;3(1):133–144. [PubMed] [Google Scholar]
  18. Pett S., Pelham A., Tizard J., Barnes N., Mieli-Vergani G., Mowat A. P., Williams R., Rolles K., Calne R. Pediatric liver transplantation: Cambridge/King's series, December 1983 to August 1986. Transplant Proc. 1987 Aug;19(4):3256–3260. [PubMed] [Google Scholar]
  19. Serrano J. A., Verougstraete C., Ghislain T. Psychological evaluation and support of pediatric patients and their parents. Transplant Proc. 1987 Aug;19(4):3358–3362. [PubMed] [Google Scholar]
  20. Stewart S. M., Uauy R., Kennard B. D., Waller D. A., Benser M., Andrews W. S. Mental development and growth in children with chronic liver disease of early and late onset. Pediatrics. 1988 Aug;82(2):167–172. [PubMed] [Google Scholar]
  21. Stewart S. M., Uauy R., Waller D. A., Kennard B. D., Andrews W. S. Mental and motor development correlates in patients with end-stage biliary atresia awaiting liver transplantation. Pediatrics. 1987 Jun;79(6):882–888. [PubMed] [Google Scholar]
  22. Stewart S. M., Uauy R., Waller D. A., Kennard B. D., Benser M., Andrews W. S. Mental and motor development, social competence, and growth one year after successful pediatric liver transplantation. J Pediatr. 1989 Apr;114(4 Pt 1):574–581. doi: 10.1016/s0022-3476(89)80696-1. [DOI] [PubMed] [Google Scholar]
  23. Tarter R. E., Erb S., Biller P. A., Switala J., Van Thiel D. H. The quality of life following liver transplantation: a preliminary report. Gastroenterol Clin North Am. 1988 Mar;17(1):207–217. [PubMed] [Google Scholar]
  24. Weichler N., Hakos L. Information needs of primary caregivers in pediatric liver transplantation. Transplant Proc. 1989 Jun;21(3):3562–3562. [PubMed] [Google Scholar]
  25. Zitelli B. J., Gartner J. C., Malatack J. J., Urbach A. H., Miller J. W., Williams L., Kirkpatrick B., Breinig M. K., Ho M. Pediatric liver transplantation: patient evaluation and selection, infectious complications, and life-style after transplantation. Transplant Proc. 1987 Aug;19(4):3309–3316. [PubMed] [Google Scholar]
  26. Zitelli B. J., Malatack J. J., Gartner J. C., Jr, Urbach A. H., Williams L., Miller J. W., Kirkpatrick B. Evaluation of the pediatric patient for liver transplantation. Pediatrics. 1986 Oct;78(4):559–565. [PubMed] [Google Scholar]
  27. Zitelli B. J., Miller J. W., Gartner J. C., Jr, Malatack J. J., Urbach A. H., Belle S. H., Williams L., Kirkpatrick B., Starzl T. E. Changes in life-style after liver transplantation. Pediatrics. 1988 Aug;82(2):173–180. [PMC free article] [PubMed] [Google Scholar]

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