Skip to main content
Journal of the Royal Society of Medicine logoLink to Journal of the Royal Society of Medicine
. 1992 Jan;85(1):53–57. doi: 10.1177/014107689208500122

Immunological mechanisms of demyelination.

R A Hughes
PMCID: PMC1293469  PMID: 1548665

Full text

PDF
53

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Baba H., Daune G. C., Ilyas A. A., Pestronk A., Cornblath D. R., Chaudhry V., Griffin J. W., Quarles R. H. Anti-GM1 ganglioside antibodies with differing fine specificities in patients with multifocal motor neuropathy. J Neuroimmunol. 1989 Dec;25(2-3):143–150. doi: 10.1016/0165-5728(89)90131-8. [DOI] [PubMed] [Google Scholar]
  2. Bradbury M. W. The structure and function of the blood-brain barrier. Fed Proc. 1984 Feb;43(2):186–190. [PubMed] [Google Scholar]
  3. Broadwell R. D. Transcytosis of macromolecules through the blood-brain barrier: a cell biological perspective and critical appraisal. Acta Neuropathol. 1989;79(2):117–128. doi: 10.1007/BF00294368. [DOI] [PubMed] [Google Scholar]
  4. Compston A., Scolding N., Wren D., Noble M. The pathogenesis of demyelinating disease: insights from cell biology. Trends Neurosci. 1991 May;14(5):175–182. doi: 10.1016/0166-2236(91)90099-g. [DOI] [PubMed] [Google Scholar]
  5. Cross A. H., Cannella B., Brosnan C. F., Raine C. S. Homing to central nervous system vasculature by antigen-specific lymphocytes. I. Localization of 14C-labeled cells during acute, chronic, and relapsing experimental allergic encephalomyelitis. Lab Invest. 1990 Aug;63(2):162–170. [PubMed] [Google Scholar]
  6. Gay D., Esiri M. Blood-brain barrier damage in acute multiple sclerosis plaques. An immunocytological study. Brain. 1991 Feb;114(Pt 1B):557–572. doi: 10.1093/brain/114.1.557. [DOI] [PubMed] [Google Scholar]
  7. Gregson N. A., Leibowitz S. IgM paraproteinaemia, polyneuropathy and myelin-associated glycoprotein (MAG). Neuropathol Appl Neurobiol. 1985 Sep-Oct;11(5):329–347. doi: 10.1111/j.1365-2990.1985.tb00030.x. [DOI] [PubMed] [Google Scholar]
  8. Hartung H. P., Schäfer B., Heininger K., Stoll G., Toyka K. V. The role of macrophages and eicosanoids in the pathogenesis of experimental allergic neuritis. Serial clinical, electrophysiological, biochemical and morphological observations. Brain. 1988 Oct;111(Pt 5):1039–1059. doi: 10.1093/brain/111.5.1039. [DOI] [PubMed] [Google Scholar]
  9. Hartung H. P., Schäfer B., Heininger K., Toyka K. V. Suppression of experimental autoimmune neuritis by the oxygen radical scavengers superoxide dismutase and catalase. Ann Neurol. 1988 May;23(5):453–460. doi: 10.1002/ana.410230505. [DOI] [PubMed] [Google Scholar]
  10. Hartung H. P., Schäfer B., van der Meide P. H., Fierz W., Heininger K., Toyka K. V. The role of interferon-gamma in the pathogenesis of experimental autoimmune disease of the peripheral nervous system. Ann Neurol. 1990 Mar;27(3):247–257. doi: 10.1002/ana.410270306. [DOI] [PubMed] [Google Scholar]
  11. Ilyas A. A., Mithen F. A., Chen Z. W., Cook S. D. Search for antibodies to neutral glycolipids in sera of patients with Guillain-Barré syndrome. J Neurol Sci. 1991 Mar;102(1):67–75. doi: 10.1016/0022-510x(91)90095-o. [DOI] [PubMed] [Google Scholar]
  12. Ilyas A. A., Willison H. J., Dalakas M. C., Whitaker J. N., Quarles R. H. Identification and characterization of gangliosides reacting with IgM paraproteins in three patients with neuropathy associated with biclonal gammopathy. J Neurochem. 1988 Sep;51(3):851–858. doi: 10.1111/j.1471-4159.1988.tb01821.x. [DOI] [PubMed] [Google Scholar]
  13. Ilyas A. A., Willison H. J., Quarles R. H., Jungalwala F. B., Cornblath D. R., Trapp B. D., Griffin D. E., Griffin J. W., McKhann G. M. Serum antibodies to gangliosides in Guillain-Barré syndrome. Ann Neurol. 1988 May;23(5):440–447. doi: 10.1002/ana.410230503. [DOI] [PubMed] [Google Scholar]
  14. Koski C. L., Chou D. K., Jungalwala F. B. Anti-peripheral nerve myelin antibodies in Guillain-Barre syndrome bind a neutral glycolipid of peripheral myelin and cross-react with Forssman antigen. J Clin Invest. 1989 Jul;84(1):280–287. doi: 10.1172/JCI114152. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Lamont A. G., Sette A., Fujinami R., Colón S. M., Miles C., Grey H. M. Inhibition of experimental autoimmune encephalomyelitis induction in SJL/J mice by using a peptide with high affinity for IAs molecules. J Immunol. 1990 Sep 15;145(6):1687–1693. [PubMed] [Google Scholar]
  16. Latov N., Hays A. P., Donofrio P. D., Liao J., Ito H., McGinnis S., Konstadoulakis M., Freddo L., Shy M. E., Manoussos K. Monoclonal IgM with unique specificity to gangliosides GM1 and GD1b and to lacto-N-tetraose associated with human motor neuron disease. Neurology. 1988 May;38(5):763–768. doi: 10.1212/wnl.38.5.763. [DOI] [PubMed] [Google Scholar]
  17. Male D., Pyrce G., Hughes C., Lantos P. Lymphocyte migration into brain modelled in vitro: control by lymphocyte activation, cytokines, and antigen. Cell Immunol. 1990 Apr 15;127(1):1–11. doi: 10.1016/0008-8749(90)90109-5. [DOI] [PubMed] [Google Scholar]
  18. Marcus D. M., Latov N., Hsi B. P., Gillard B. K. Measurement and significance of antibodies against GM1 ganglioside. Report of a workshop, 18 April 1989, Chicago, IL, U.S.A. J Neuroimmunol. 1989 Dec;25(2-3):255–259. doi: 10.1016/0165-5728(89)90144-6. [DOI] [PubMed] [Google Scholar]
  19. Pestronk A., Adams R. N., Clawson L., Cornblath D., Kuncl R. W., Griffin D., Drachman D. B. Serum antibodies to GM1 ganglioside in amyotrophic lateral sclerosis. Neurology. 1988 Sep;38(9):1457–1461. doi: 10.1212/wnl.38.9.1457. [DOI] [PubMed] [Google Scholar]
  20. Pestronk A., Cornblath D. R., Ilyas A. A., Baba H., Quarles R. H., Griffin J. W., Alderson K., Adams R. N. A treatable multifocal motor neuropathy with antibodies to GM1 ganglioside. Ann Neurol. 1988 Jul;24(1):73–78. doi: 10.1002/ana.410240113. [DOI] [PubMed] [Google Scholar]
  21. Quarles R. H., Ilyas A. A., Willison H. J. Antibodies to glycolipids in demyelinating diseases of the human peripheral nervous system. Chem Phys Lipids. 1986 Dec 15;42(1-3):235–248. doi: 10.1016/0009-3084(86)90055-1. [DOI] [PubMed] [Google Scholar]
  22. Schwartz R. H. Immune response (Ir) genes of the murine major histocompatibility complex. Adv Immunol. 1986;38:31–201. doi: 10.1016/s0065-2776(08)60006-1. [DOI] [PubMed] [Google Scholar]
  23. Scolding N. J., Compston D. A. Oligodendrocyte-macrophage interactions in vitro triggered by specific antibodies. Immunology. 1991 Jan;72(1):127–132. [PMC free article] [PubMed] [Google Scholar]
  24. Scolding N. J., Morgan B. P., Houston W. A., Linington C., Campbell A. K., Compston D. A. Vesicular removal by oligodendrocytes of membrane attack complexes formed by activated complement. Nature. 1989 Jun 22;339(6226):620–622. doi: 10.1038/339620a0. [DOI] [PubMed] [Google Scholar]
  25. Sedgwick J. D., Hughes C. C., Male D. K., MacPhee I. A., ter Meulen V. Antigen-specific damage to brain vascular endothelial cells mediated by encephalitogenic and nonencephalitogenic CD4+ T cell lines in vitro. J Immunol. 1990 Oct 15;145(8):2474–2481. [PubMed] [Google Scholar]
  26. Sobue G., Yamoto S., Hirayama M., Matsuoka Y., Uematsu H., Sobue I. The role of macrophages in demyelination in experimental allergic neuritis. J Neurol Sci. 1982 Oct;56(1):75–87. doi: 10.1016/0022-510x(82)90062-4. [DOI] [PubMed] [Google Scholar]
  27. Stoll G., Schmidt B., Jander S., Toyka K. V., Hartung H. P. Presence of the terminal complement complex (C5b-9) precedes myelin degradation in immune-mediated demyelination of the rat peripheral nervous system. Ann Neurol. 1991 Aug;30(2):147–155. doi: 10.1002/ana.410300205. [DOI] [PubMed] [Google Scholar]
  28. Trotter J., Smith M. E. The role of phospholipases from inflammatory macrophages in demyelination. Neurochem Res. 1986 Mar;11(3):349–361. doi: 10.1007/BF00965009. [DOI] [PubMed] [Google Scholar]
  29. Urban J. L., Horvath S. J., Hood L. Autoimmune T cells: immune recognition of normal and variant peptide epitopes and peptide-based therapy. Cell. 1989 Oct 20;59(2):257–271. doi: 10.1016/0092-8674(89)90288-2. [DOI] [PubMed] [Google Scholar]
  30. Wraith D. C., McDevitt H. O., Steinman L., Acha-Orbea H. T cell recognition as the target for immune intervention in autoimmune disease. Cell. 1989 Jun 2;57(5):709–715. doi: 10.1016/0092-8674(89)90786-1. [DOI] [PubMed] [Google Scholar]
  31. Wraith D. C., Smilek D. E., Mitchell D. J., Steinman L., McDevitt H. O. Antigen recognition in autoimmune encephalomyelitis and the potential for peptide-mediated immunotherapy. Cell. 1989 Oct 20;59(2):247–255. doi: 10.1016/0092-8674(89)90287-0. [DOI] [PubMed] [Google Scholar]

Articles from Journal of the Royal Society of Medicine are provided here courtesy of Royal Society of Medicine Press

RESOURCES