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Journal of the Royal Society of Medicine logoLink to Journal of the Royal Society of Medicine
. 1992 Jun;85(6):346–349.

Cerumen: its fascination and clinical importance: a review.

H C Hanger 1, G P Mulley 1
PMCID: PMC1293500  PMID: 1625268

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Alfred B. M., Stout T. D., Lee M., Birkbeck J., Petrakis N. L. Blood groups, phosphoglucomutase, and cerumen types of the Anaham (Chilcotin) Indians. Am J Phys Anthropol. 1970 May;32(3):329–337. doi: 10.1002/ajpa.1330320303. [DOI] [PubMed] [Google Scholar]
  2. Anand J. K., Court I. Hearing loss leading to impaired ability to communicate in residents of homes for the elderly. BMJ. 1989 May 27;298(6685):1429–1430. doi: 10.1136/bmj.298.6685.1429-a. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Anderson R. G., Meyerhoff W. L. Otologic manifestations of aging. Otolaryngol Clin North Am. 1982 May;15(2):353–370. [PubMed] [Google Scholar]
  4. Bass E. J., Jackson J. F. Cerumen types in Eskimos. Am J Phys Anthropol. 1977 Sep;47(2):209–210. doi: 10.1002/ajpa.1330470203. [DOI] [PubMed] [Google Scholar]
  5. Baxter P. Association between use of cotton tipped swabs and cerumen plugs. Br Med J (Clin Res Ed) 1983 Oct 29;287(6401):1260–1260. doi: 10.1136/bmj.287.6401.1260. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Bellini M. J., Terry R. M., Lewis F. A. An evaluation of common cerumenolytic agents: an in-vitro study. Clin Otolaryngol Allied Sci. 1989 Feb;14(1):23–25. doi: 10.1111/j.1365-2273.1989.tb00332.x. [DOI] [PubMed] [Google Scholar]
  7. Bende M. Human ceruminous gland innervation. J Laryngol Otol. 1981 Jan;95(1):11–15. doi: 10.1017/s0022215100090344. [DOI] [PubMed] [Google Scholar]
  8. Brand-Auraban A., Kopito L., Shwachman H. Chemical analysis of some inorganic elements in cerumen from patients with cystic fibrosis. J Invest Dermatol. 1972 Jan;58(1):14–15. doi: 10.1111/1523-1747.ep13077196. [DOI] [PubMed] [Google Scholar]
  9. Burgess E. H. Earwax - and the right way to use an ear syringe. Nurs Times. 1977 Oct 6;73(40):1564–1565. [PubMed] [Google Scholar]
  10. Carne S. Ear syringing. Br Med J. 1980 Feb 9;280(6211):374–376. doi: 10.1136/bmj.280.6211.374. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Chai T. J., Chai T. C. Bactericidal activity of cerumen. Antimicrob Agents Chemother. 1980 Oct;18(4):638–641. doi: 10.1128/aac.18.4.638. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Chaput de Saintonge D. M., Johnstone C. I. A clinical comparison of triethanolamine polypeptide oleate-condensate ear drops with olive oil for the removal of impacted wax. Br J Clin Pract. 1973 Dec;27(12):454–455. [PubMed] [Google Scholar]
  13. Donnan F. de S. Clinical experience of 'xerumenex' in the removal of ear wax. Practitioner. 1968 Apr;200(198):574–577. [PubMed] [Google Scholar]
  14. El-Ghazzawi E. F., Talaat M., Mandour M. A., Arafa S. A. The ceruminous glands in chronic suppurative otitis media. A histological and histochemical study. J Laryngol Otol. 1979 Aug;93(8):785–791. doi: 10.1017/s0022215100087727. [DOI] [PubMed] [Google Scholar]
  15. Fahmy S., Whitefield M. Multicentre clinical trial of Exterol as a cerumenolytic. Br J Clin Pract. 1982 May;36(5):197–204. [PubMed] [Google Scholar]
  16. Fairbanks D. N. Otic topical agents. Otolaryngol Head Neck Surg. 1980 Jul-Aug;88(4):327–331. doi: 10.1177/019459988008800401. [DOI] [PubMed] [Google Scholar]
  17. Fairey A., Freer C. B., Machin D. Ear wax and otitis media in children. Br Med J (Clin Res Ed) 1985 Aug 10;291(6492):387–388. doi: 10.1136/bmj.291.6492.387. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Fraser J. G. The efficacy of wax solvents: in vitro studies and a clinical trial. J Laryngol Otol. 1970 Oct;84(10):1055–1064. doi: 10.1017/s0022215100072856. [DOI] [PubMed] [Google Scholar]
  19. Gregg J. B. Ruminations upon cerumen: dry vs wet; Indian vs Caucasian. S D J Med. 1985 May;38(5):23–27. [PubMed] [Google Scholar]
  20. Herbst K. G., Humphrey C. Hearing impairment and mental state in the elderly living at home. Br Med J. 1980 Oct 4;281(6245):903–905. doi: 10.1136/bmj.281.6245.903. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Hyslop N. E., Jr Ear wax and host defense. N Engl J Med. 1971 May 13;284(19):1099–1100. doi: 10.1056/NEJM197105132841913. [DOI] [PubMed] [Google Scholar]
  22. Ing R., Petrakis L., Ho H. C. Evidence against association between wet cerumen and breast cancer. Lancet. 1973 Jan 6;1(7793):41–41. doi: 10.1016/s0140-6736(73)91252-x. [DOI] [PubMed] [Google Scholar]
  23. Jaffé G., Grimshaw J. A multicentric clinical trial comparing Otocerol with Cerumol as cerumenolytics. J Int Med Res. 1978;6(3):241–244. doi: 10.1177/030006057800600312. [DOI] [PubMed] [Google Scholar]
  24. Kikuchi I. The cerumen type and hemodialysis. J Dermatol. 1985 Apr;12(2):201–201. doi: 10.1111/j.1346-8138.1985.tb01561.x. [DOI] [PubMed] [Google Scholar]
  25. Liston S. L. Ear wax and the otolaryngologist. Anesthesiology. 1985 Nov;63(5):566–566. doi: 10.1097/00000542-198511000-00026. [DOI] [PubMed] [Google Scholar]
  26. Makino K., Amatsu M. Epithelial migration on the tympanic membrane and external canal. Arch Otorhinolaryngol. 1986;243(1):39–42. doi: 10.1007/BF00457906. [DOI] [PubMed] [Google Scholar]
  27. Mandour M. A., El-Ghazzawi E. F., Toppozada H. H., Malaty H. A. Histological and histochemical study of the activity of ceruminous glands in normal and excessive wax accumulation. J Laryngol Otol. 1974 Nov;88(11):1075–1085. doi: 10.1017/s0022215100079767. [DOI] [PubMed] [Google Scholar]
  28. Mehta A. K. An in-vitro comparison of the disintegration of human ear wax by five cerumenolytics commonly used in general practice. Br J Clin Pract. 1985 May;39(5):200–203. [PubMed] [Google Scholar]
  29. Mulrow C. D., Aguilar C., Endicott J. E., Velez R., Tuley M. R., Charlip W. S., Hill J. A. Association between hearing impairment and the quality of life of elderly individuals. J Am Geriatr Soc. 1990 Jan;38(1):45–50. doi: 10.1111/j.1532-5415.1990.tb01595.x. [DOI] [PubMed] [Google Scholar]
  30. ONUAGULUCHI G. Crises in post-encephalitic Parkinsonism. Brain. 1961 Sep;84:395–414. doi: 10.1093/brain/84.3.395. [DOI] [PubMed] [Google Scholar]
  31. Ono T., Jono M., Kuriya N. Tinea versicolor and earwax. J Dermatol. 1981 Feb;8(1):75–78. doi: 10.1111/j.1346-8138.1981.tb02015.x. [DOI] [PubMed] [Google Scholar]
  32. Petrakis N. L. Cerumen phenotype and epithelial dysplasia in nipple aspirates of breast fluid. Am J Phys Anthropol. 1983 Sep;62(1):115–118. doi: 10.1002/ajpa.1330620115. [DOI] [PubMed] [Google Scholar]
  33. Petrakis N. L., Pingle U., Petrakis S. J., Petrakis S. L. Evidence for a genetic cline in earwax types in the Middle East and Southeast Asia. Am J Phys Anthropol. 1971 Jul;35(1):141–144. doi: 10.1002/ajpa.1330350117. [DOI] [PubMed] [Google Scholar]
  34. Petrakis N. L., Wiesenfeld S. L., Flander L. Possible influence of age on the expression of the heterozygous cerumen phenotype. Am J Phys Anthropol. 1986 Apr;69(4):437–440. doi: 10.1002/ajpa.1330690403. [DOI] [PubMed] [Google Scholar]
  35. Proudfoot J. Clinical trial of a ceruminolytic agent in general practice. Br J Clin Pract. 1968 Feb;22(2):69–70. [PubMed] [Google Scholar]
  36. Raman R. Impacted ear wax--a cause for unexplained cough? Arch Otolaryngol Head Neck Surg. 1986 Jun;112(6):679–679. doi: 10.1001/archotol.1986.03780060091020. [DOI] [PubMed] [Google Scholar]
  37. Robinson A. C., Hawke M., Naiberg J. Impacted cerumen: a disorder of keratinocyte separation in the superficial external ear canal? J Otolaryngol. 1990 Apr;19(2):86–90. [PubMed] [Google Scholar]
  38. Salomon G., Vesterager V., Jagd M. Age-related hearing difficulties. I. Hearing impairment, disability, and handicap--a controlled study. Audiology. 1988;27(3):164–178. doi: 10.3109/00206098809081587. [DOI] [PubMed] [Google Scholar]
  39. Schwartz R. H., Rodriguez W. J., McAveney W., Grundfast K. M. Cerumen removal. How necessary is it to diagnose acute otitis media? Am J Dis Child. 1983 Nov;137(11):1064–1065. doi: 10.1001/archpedi.1983.02140370026009. [DOI] [PubMed] [Google Scholar]
  40. Sharp J. F., Wilson J. A., Ross L., Barr-Hamilton R. M. Ear wax removal: a survey of current practice. BMJ. 1990 Dec 1;301(6763):1251–1253. doi: 10.1136/bmj.301.6763.1251. [DOI] [PMC free article] [PubMed] [Google Scholar]
  41. Shichijo S., Masuda H., Takeuchi M. Carbohydrate composition of glycopeptides from the human cerumen. Biochem Med. 1979 Oct;22(2):256–263. doi: 10.1016/0006-2944(79)90011-5. [DOI] [PubMed] [Google Scholar]
  42. Shugyo Y., Sudo N., Kanai K., Yamashita T., Kumazawa T., Kanamura S. Morphological differences between secretory cells of wet and dry types of human ceruminous glands. Am J Anat. 1988 Apr;181(4):377–384. doi: 10.1002/aja.1001810405. [DOI] [PubMed] [Google Scholar]
  43. Sim D. W. Wax plugs and cotton buds. J Laryngol Otol. 1988 Jul;102(7):575–576. doi: 10.1017/s0022215100105742. [DOI] [PubMed] [Google Scholar]
  44. Srsen S. Dark pigmentation of ear cerumen in alkaptonuria. Lancet. 1978 Sep 9;2(8089):577–577. doi: 10.1016/s0140-6736(78)92912-4. [DOI] [PubMed] [Google Scholar]
  45. Stone M., Fulghum R. S. Bactericidal activity of wet cerumen. Ann Otol Rhinol Laryngol. 1984 Mar-Apr;93(2 Pt 1):183–186. doi: 10.1177/000348948409300217. [DOI] [PubMed] [Google Scholar]
  46. Warwick-Brown N. P. Wax impaction in the ear. Practitioner. 1986 Apr;230(1414):301–301. [PubMed] [Google Scholar]
  47. Wax softening with a new preparation. Practitioner. 1967 Sep;199(191):359–362. [PubMed] [Google Scholar]
  48. el-Silimy O. E., Gibbin K. P. Ear wax and otitis media in children. Br Med J (Clin Res Ed) 1985 Aug 31;291(6495):601–602. doi: 10.1136/bmj.291.6495.601-c. [DOI] [PMC free article] [PubMed] [Google Scholar]

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