Skip to main content
Journal of the Royal Society of Medicine logoLink to Journal of the Royal Society of Medicine
. 1992 Jul;85(7):373–376.

Pathogenesis of multiple sclerosis.

R A Hughes
PMCID: PMC1293538  PMID: 1629842

Full text

PDF
373

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Adams C. W., Poston R. N., Buk S. J., Sidhu Y. S., Vipond H. Inflammatory vasculitis in multiple sclerosis. J Neurol Sci. 1985 Jul;69(3):269–283. doi: 10.1016/0022-510x(85)90139-x. [DOI] [PubMed] [Google Scholar]
  2. Arnon R., Crisp E., Kelley R., Ellison G. W., Myers L. W., Tourtellotte W. W. Anti-ganglioside antibodies in multiple sclerosis. J Neurol Sci. 1980 May;46(2):179–186. doi: 10.1016/0022-510x(80)90076-3. [DOI] [PubMed] [Google Scholar]
  3. Beall S. S., Concannon P., Charmley P., McFarland H. F., Gatti R. A., Hood L. E., McFarlin D. E., Biddison W. E. The germline repertoire of T cell receptor beta-chain genes in patients with chronic progressive multiple sclerosis. J Neuroimmunol. 1989 Jan;21(1):59–66. doi: 10.1016/0165-5728(89)90159-8. [DOI] [PubMed] [Google Scholar]
  4. Bradbury K., Aparicio S. R., Sumner D. W., Macfie A., Sagar P., Griffin N. R., Bird C. C. Comparison of in vitro demyelination and cytotoxicity of humoral factors in multiple sclerosis and other neurological diseases. J Neurol Sci. 1985 Sep;70(2):167–181. doi: 10.1016/0022-510x(85)90085-1. [DOI] [PubMed] [Google Scholar]
  5. Charmley P., Beall S. S., Concannon P., Hood L., Gatti R. A. Further localization of a multiple sclerosis susceptibility gene on chromosome 7q using a new T cell receptor beta-chain DNA polymorphism. J Neuroimmunol. 1991 Jun;32(3):231–240. doi: 10.1016/0165-5728(91)90193-b. [DOI] [PubMed] [Google Scholar]
  6. Cross A. H., Cannella B., Brosnan C. F., Raine C. S. Homing to central nervous system vasculature by antigen-specific lymphocytes. I. Localization of 14C-labeled cells during acute, chronic, and relapsing experimental allergic encephalomyelitis. Lab Invest. 1990 Aug;63(2):162–170. [PubMed] [Google Scholar]
  7. Elian M., Nightingale S., Dean G. Multiple sclerosis among United Kingdom-born children of immigrants from the Indian subcontinent, Africa and the West Indies. J Neurol Neurosurg Psychiatry. 1990 Oct;53(10):906–911. doi: 10.1136/jnnp.53.10.906. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Fujinami R. S., Oldstone M. B. Amino acid homology between the encephalitogenic site of myelin basic protein and virus: mechanism for autoimmunity. Science. 1985 Nov 29;230(4729):1043–1045. doi: 10.1126/science.2414848. [DOI] [PubMed] [Google Scholar]
  9. Fujinami R. S., Oldstone M. B., Wroblewska Z., Frankel M. E., Koprowski H. Molecular mimicry in virus infection: crossreaction of measles virus phosphoprotein or of herpes simplex virus protein with human intermediate filaments. Proc Natl Acad Sci U S A. 1983 Apr;80(8):2346–2350. doi: 10.1073/pnas.80.8.2346. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Gay D., Dick G., Upton G. Multiple sclerosis associated with sinusitis: case-controlled study in general practice. Lancet. 1986 Apr 12;1(8485):815–819. doi: 10.1016/s0140-6736(86)90936-0. [DOI] [PubMed] [Google Scholar]
  11. Gay D., Esiri M. Blood-brain barrier damage in acute multiple sclerosis plaques. An immunocytological study. Brain. 1991 Feb;114(Pt 1B):557–572. doi: 10.1093/brain/114.1.557. [DOI] [PubMed] [Google Scholar]
  12. Goban Y., Saida T., Saida K., Nishitani H., Kameyama M. Role of nonspecific myelin destruction by delayed type hypersensitivity in primary demyelination. J Neurol Sci. 1986 Jun;74(1):97–109. doi: 10.1016/0022-510x(86)90194-2. [DOI] [PubMed] [Google Scholar]
  13. Graham E. M., Francis D. A., Sanders M. D., Rudge P. Ocular inflammatory changes in established multiple sclerosis. J Neurol Neurosurg Psychiatry. 1989 Dec;52(12):1360–1363. doi: 10.1136/jnnp.52.12.1360. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Hillert J., Leng C., Olerup O. No association with germline T cell receptor beta-chain gene alleles or haplotypes in Swedish patients with multiple sclerosis. J Neuroimmunol. 1991 May;32(2):141–147. doi: 10.1016/0165-5728(91)90006-s. [DOI] [PubMed] [Google Scholar]
  15. Hughes R. A., Gray I. A., Clifford-Jones R., Stern M. A. Lymphocyte transformation in the presence of myelin basic protein in multiple sclerosis and control subjects. Acta Neurol Scand. 1979 Aug;60(2):65–76. doi: 10.1111/j.1600-0404.1979.tb02953.x. [DOI] [PubMed] [Google Scholar]
  16. Hughes R. A. Prospects for the treatment of multiple sclerosis. J R Soc Med. 1991 Feb;84(2):63–65. doi: 10.1177/014107689108400201. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Jahnke U., Fischer E. H., Alvord E. C., Jr Sequence homology between certain viral proteins and proteins related to encephalomyelitis and neuritis. Science. 1985 Jul 19;229(4710):282–284. doi: 10.1126/science.2409602. [DOI] [PubMed] [Google Scholar]
  18. Lee S. J., Wucherpfennig K. W., Brod S. A., Benjamin D., Weiner H. L., Hafler D. A. Common T-cell receptor V beta usage in oligoclonal T lymphocytes derived from cerebrospinal fluid and blood of patients with multiple sclerosis. Ann Neurol. 1991 Jan;29(1):33–40. doi: 10.1002/ana.410290109. [DOI] [PubMed] [Google Scholar]
  19. Liblau R., Tournier-Lasserve E., Maciazek J., Dumas G., Siffert O., Hashim G., Bach M. A. T cell response to myelin basic protein epitopes in multiple sclerosis patients and healthy subjects. Eur J Immunol. 1991 Jun;21(6):1391–1395. doi: 10.1002/eji.1830210610. [DOI] [PubMed] [Google Scholar]
  20. Linington C., Bradl M., Lassmann H., Brunner C., Vass K. Augmentation of demyelination in rat acute allergic encephalomyelitis by circulating mouse monoclonal antibodies directed against a myelin/oligodendrocyte glycoprotein. Am J Pathol. 1988 Mar;130(3):443–454. [PMC free article] [PubMed] [Google Scholar]
  21. Martyn C. N., Colquhoun I. Radiological evidence of sinus infection in patients with multiple sclerosis. J Neurol Neurosurg Psychiatry. 1991 Oct;54(10):925–926. doi: 10.1136/jnnp.54.10.925. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Miller D. H., Rudge P., Johnson G., Kendall B. E., Macmanus D. G., Moseley I. F., Barnes D., McDonald W. I. Serial gadolinium enhanced magnetic resonance imaging in multiple sclerosis. Brain. 1988 Aug;111(Pt 4):927–939. doi: 10.1093/brain/111.4.927. [DOI] [PubMed] [Google Scholar]
  23. Operskalski E. A., Visscher B. R., Malmgren R. M., Detels R. A case-control study of multiple sclerosis. Neurology. 1989 Jun;39(6):825–829. doi: 10.1212/wnl.39.6.825. [DOI] [PubMed] [Google Scholar]
  24. Panitch H. S., Hirsch R. L., Haley A. S., Johnson K. P. Exacerbations of multiple sclerosis in patients treated with gamma interferon. Lancet. 1987 Apr 18;1(8538):893–895. doi: 10.1016/s0140-6736(87)92863-7. [DOI] [PubMed] [Google Scholar]
  25. Pette M., Fujita K., Kitze B., Whitaker J. N., Albert E., Kappos L., Wekerle H. Myelin basic protein-specific T lymphocyte lines from MS patients and healthy individuals. Neurology. 1990 Nov;40(11):1770–1776. doi: 10.1212/wnl.40.11.1770. [DOI] [PubMed] [Google Scholar]
  26. Phadke J. G., Downie A. W. Epidemiology of multiple sclerosis in the north-east (Grampian region) of Scotland--an update. J Epidemiol Community Health. 1987 Mar;41(1):5–13. doi: 10.1136/jech.41.1.5. [DOI] [PMC free article] [PubMed] [Google Scholar]
  27. Poser C. M. Multiple sclerosis. Observations and reflections--a personal memoir. J Neurol Sci. 1992 Feb;107(2):127–140. doi: 10.1016/0022-510x(92)90280-x. [DOI] [PubMed] [Google Scholar]
  28. Powell H. C., Braheny S. L., Hughes R. A., Lampert P. W. Antigen-specific demyelination and significance of the bystander effect in peripheral nerves. Am J Pathol. 1984 Mar;114(3):443–453. [PMC free article] [PubMed] [Google Scholar]
  29. Roberts M. H., Martin J. P., McLellan D. L., McIntosh-Michaelis S. A., Spackman A. J. The prevalence of multiple sclerosis in the Southampton and South West Hampshire Health Authority. J Neurol Neurosurg Psychiatry. 1991 Jan;54(1):55–59. doi: 10.1136/jnnp.54.1.55. [DOI] [PMC free article] [PubMed] [Google Scholar]
  30. Sadovnick A. D., Baird P. A., Ward R. H. Multiple sclerosis: updated risks for relatives. Am J Med Genet. 1988 Mar;29(3):533–541. doi: 10.1002/ajmg.1320290310. [DOI] [PubMed] [Google Scholar]
  31. Sibley W. A., Bamford C. R., Clark K. Clinical viral infections and multiple sclerosis. Lancet. 1985 Jun 8;1(8441):1313–1315. doi: 10.1016/S0140-6736(85)92801-6. [DOI] [PMC free article] [PubMed] [Google Scholar]
  32. Stoner G. L., Brosnan C. F., Wisniewski H. M., Bloom B. R. Studies on demyelination by activated lymphocytes in the rabbit eye. I. Effects of a mononuclear cell infiltrate induced by products of activated lymphocytes. J Immunol. 1977 Jun;118(6):2094–2102. [PubMed] [Google Scholar]
  33. Trotter J. L., Hickey W. F., van der Veen R. C., Sulze L. Peripheral blood mononuclear cells from multiple sclerosis patients recognize myelin proteolipid protein and selected peptides. J Neuroimmunol. 1991 Jul;33(1):55–62. doi: 10.1016/0165-5728(91)90034-5. [DOI] [PubMed] [Google Scholar]
  34. Wajgt A., Górny M. CSF antibodies to myelin basic protein and to myelin-associated glycoprotein in multiple sclerosis. Evidence of the intrathecal production of antibodies. Acta Neurol Scand. 1983 Nov;68(5):337–343. doi: 10.1111/j.1600-0404.1983.tb04841.x. [DOI] [PubMed] [Google Scholar]
  35. Walter M. A., Gibson W. T., Ebers G. C., Cox D. W. Susceptibility to multiple sclerosis is associated with the proximal immunoglobulin heavy chain variable region. J Clin Invest. 1991 Apr;87(4):1266–1273. doi: 10.1172/JCI115128. [DOI] [PMC free article] [PubMed] [Google Scholar]
  36. Warren K. G., Catz I. Purification of autoantibodies to myelin basic protein by antigen specific affinity chromatography from cerebrospinal fluid IgG of multiple sclerosis patients. Immunoreactivity studies with human myelin basic protein. J Neurol Sci. 1991 May;103(1):90–96. doi: 10.1016/0022-510x(91)90289-j. [DOI] [PubMed] [Google Scholar]
  37. Williams E. S., McKeran R. O. Prevalence of multiple sclerosis in a south London borough. Br Med J (Clin Res Ed) 1986 Jul 26;293(6541):237–239. doi: 10.1136/bmj.293.6541.237. [DOI] [PMC free article] [PubMed] [Google Scholar]
  38. Wisniewski H. M., Bloom B. R. Primary demyelination as a nonspecific consequence of a cell-mediated immune reaction. J Exp Med. 1975 Feb 1;141(2):346–359. doi: 10.1084/jem.141.2.346. [DOI] [PMC free article] [PubMed] [Google Scholar]
  39. Xiao B. G., Linington C., Link H. Antibodies to myelin-oligodendrocyte glycoprotein in cerebrospinal fluid from patients with multiple sclerosis and controls. J Neuroimmunol. 1991 Feb;31(2):91–96. doi: 10.1016/0165-5728(91)90014-x. [DOI] [PubMed] [Google Scholar]
  40. Yudkin P. L., Ellison G. W., Ghezzi A., Goodkin D. E., Hughes R. A., McPherson K., Mertin J., Milanese C. Overview of azathioprine treatment in multiple sclerosis. Lancet. 1991 Oct 26;338(8774):1051–1055. doi: 10.1016/0140-6736(91)91909-e. [DOI] [PubMed] [Google Scholar]

Articles from Journal of the Royal Society of Medicine are provided here courtesy of Royal Society of Medicine Press

RESOURCES