Abstract
The origin of this unusual variant of carcinoma of the prostate has provoked discussion ever since its first description in 1967. This is of both embryological interest and therapeutic importance. Four cases have been reviewed, and all have demonstrated immunohistochemical features consistent with an origin from prostatic tissue. In addition, three had evidence of disseminated disease which responded well to androgen ablation. It is concluded that the term endometrioid carcinoma is of descriptive value only, and these tumours are a variant of primary duct prostatic carcinoma. Patients should be treated by androgen ablation when metastases are present.
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- Dube V. E., Farrow G. M., Greene L. F. Prostatic adenocarcinoma of ductal origin. Cancer. 1973 Aug;32(2):402–409. doi: 10.1002/1097-0142(197308)32:2<402::aid-cncr2820320218>3.0.co;2-q. [DOI] [PubMed] [Google Scholar]
- Epstein J. I., Woodruff J. M. Adenocarcinoma of the prostate with endometrioid features. A light microscopic and immunohistochemical study of ten cases. Cancer. 1986 Jan 1;57(1):111–119. doi: 10.1002/1097-0142(19860101)57:1<111::aid-cncr2820570123>3.0.co;2-n. [DOI] [PubMed] [Google Scholar]
- Gillatt D. A., O'Reilly P. H., Reeve N. L. Endometrioid carcinoma of the prostatic utricle. Br J Urol. 1986 Oct;58(5):559–560. doi: 10.1111/j.1464-410x.1986.tb05471.x. [DOI] [PubMed] [Google Scholar]
- Jöbsis A. C., De Vries G. P., Anholt R. R., Sanders G. T. Demonstration of the prostatic origin of metastases: an immunohistochemical method for formalin-fixed embedded tissue. Cancer. 1978 May;41(5):1788–1793. doi: 10.1002/1097-0142(197805)41:5<1788::aid-cncr2820410521>3.0.co;2-d. [DOI] [PubMed] [Google Scholar]
- Melicow M. M., Pachter M. R. Endometrial carcinoma of proxtatic utricle (uterus masculinus). Cancer. 1967 Oct;20(10):1715–1722. doi: 10.1002/1097-0142(196710)20:10<1715::aid-cncr2820201022>3.0.co;2-e. [DOI] [PubMed] [Google Scholar]
- Melicow M. M., Tannenbaum M. Endometrial carcinoma of uterus masculinus (prostatic utricle). Report of 6 cases. J Urol. 1971 Dec;106(6):892–902. doi: 10.1016/s0022-5347(17)61430-7. [DOI] [PubMed] [Google Scholar]
- Nadji M., Tabei S. Z., Castro A., Chu T. M., Morales A. R. Prostatic origin of tumors. An immunohistochemical study. Am J Clin Pathol. 1980 Jun;73(6):735–739. doi: 10.1093/ajcp/73.6.735. [DOI] [PubMed] [Google Scholar]
- Rotterdam H. Z., Melicow M. M. Double primary prostatic adenocarcinoma. Urology. 1975 Aug;6(2):245–248. doi: 10.1016/0090-4295(75)90726-8. [DOI] [PubMed] [Google Scholar]
- Tannenbaum M. Endometrial tumors and/or associated carcinomas of prostate. Urology. 1975 Sep;6(3):372–375. doi: 10.1016/0090-4295(75)90773-6. [DOI] [PubMed] [Google Scholar]
- Walker A. N., Mills S. E., Fechner R. E., Perry J. M. 'Endometrial' adenocarcinoma of the prostatic urethra arising in a villous polyp. A light microscopic and immunoperoxidase study. Arch Pathol Lab Med. 1982 Nov;106(12):624–627. [PubMed] [Google Scholar]
- Walther M. M., Nassar V., Harruff R. C., Mann B. B., Jr, Finnerty D. P., Hewen-Lowe K. O. Endometrial carcinoma of the prostatic utricle: a tumor of prostatic origin. J Urol. 1985 Oct;134(4):769–773. doi: 10.1016/s0022-5347(17)47433-7. [DOI] [PubMed] [Google Scholar]
- Zaloudek C., Williams J. W., Kempson R. L. "Endometrial" adenocarcinoma of the prostate: a distinctive tumor of probable prostatic duct origin. Cancer. 1976 May;37(5):2255–2262. doi: 10.1002/1097-0142(197605)37:5<2255::aid-cncr2820370515>3.0.co;2-e. [DOI] [PubMed] [Google Scholar]