Abstract
Bazex disease is one of the rarer cutaneous paraneoplastic syndromes. It is characterized by psoriasiform changes on the digits, and in some patients spread to the ears, nose and in later stages to the limbs and trunk. The associated malignancy is typically a squamous cell carcinoma of the upper aerodigestive tract. We review the literature regarding acrokeratosis paraneoplastica of Bazex and report three cases which illustrate both the typical and some of the less common changes that are seen in the condition.
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- Bazex A., Griffiths A. Acrokeratosis paraneoplastica--a new cutaneous marker of malignancy. Br J Dermatol. 1980 Sep;103(3):301–306. doi: 10.1111/j.1365-2133.1980.tb07248.x. [DOI] [PubMed] [Google Scholar]
- Benson P. M., Lupton G. P., James W. D. Purpura and gangrene in a septic patient. Purpura fulminans secondary to pneumococcal sepsis. Arch Dermatol. 1988 Dec;124(12):1851–1854. doi: 10.1001/archderm.124.12.1851. [DOI] [PubMed] [Google Scholar]
- Boudoulas O., Camisa C. Paraneoplastic acrokeratosis: Bazex syndrome. Cutis. 1986 Jun;37(6):449–453. [PubMed] [Google Scholar]
- Brenner S., Brayer M., Topilsky M. Acrokeratosis paraneoplastica (Basex) in a patient with bronchial carcinoid tumor. J Am Acad Dermatol. 1987 Sep;17(3):517–518. doi: 10.1016/s0190-9622(87)80379-1. [DOI] [PubMed] [Google Scholar]
- Douglas W. S., Bilsland D. J., Howatson R. Acrokeratosis paraneoplastica of Bazex--a case in the UK. Clin Exp Dermatol. 1991 Jul;16(4):297–299. doi: 10.1111/j.1365-2230.1991.tb00381.x. [DOI] [PubMed] [Google Scholar]
- Grimwood R. E., Lekan C. Acrokeratosis paraneoplastica with esophageal squamous cell carcinoma. J Am Acad Dermatol. 1987 Oct;17(4):685–686. doi: 10.1016/s0190-9622(87)80456-5. [DOI] [PubMed] [Google Scholar]
- Hagedorn M., Stengel R. Pathogenetischer Beitrag zur Akrokeratose Bazex. Dermatologica. 1983;167(5):234–242. [PubMed] [Google Scholar]
- Le T., Pierard G. E. Etude clinique et histologique de l'effet d'un rétinoïde aromatique Ro 10-9359 sur un syndrome apparente à l'acrokératose paranéoplasique de Bazex. Dermatologica. 1982;165(6):559–567. [PubMed] [Google Scholar]
- Martin R. W., 3rd, Cornitius T. G., Naylor M. F., Neldner K. H. Bazex's syndrome in a woman with pulmonary adenocarcinoma. Arch Dermatol. 1989 Jun;125(6):847–848. [PubMed] [Google Scholar]
- Obasi O. E., Garg S. K. Bazex paraneoplastic acrokeratosis in prostate carcinoma. Br J Dermatol. 1987 Nov;117(5):647–651. doi: 10.1111/j.1365-2133.1987.tb07498.x. [DOI] [PubMed] [Google Scholar]
- Richard M., Giroux J. M. Acrokeratosis paraneoplastica (Bazex' syndrome). J Am Acad Dermatol. 1987 Jan;16(1 Pt 2):178–183. doi: 10.1016/s0190-9622(87)80057-9. [DOI] [PubMed] [Google Scholar]
- Scarpa C., Nini G., Pasqua M. C., Franchi A., Frati C. Singolare osservazione di eritroacrocheratosi paraneoplastica. G Ital Dermatol Minerva Dermatol. 1971 Jan;46(1):17–25. [PubMed] [Google Scholar]
- Wishart J. M. Bazex paraneoplastic acrokeratosis: a case report and response to Tigason. Br J Dermatol. 1986 Nov;115(5):595–599. doi: 10.1111/j.1365-2133.1986.tb05770.x. [DOI] [PubMed] [Google Scholar]



