表 1.
入组患者的基线数据
| 项目 | 总例数/例 (90例) |
百分率/% | 切缘≤2 mm/例 (25例) |
百分率/% | 切缘>2 mm/例 (65例) |
百分率/% | P |
| a采用t-tes t检验，b采用Mann-Whitney检验，c采用Chi-Square检验。 | |||||||
| 年龄/岁 | 58.0±9.0 | 39~84 | 57.9±9.2 | 40~75 | 58.0±9.0 | 39~84 | 0.927a |
| 性别 | 0.183b | ||||||
| 男 | 60 | 66.7 | 14 | 56.0 | 46 | 70.8 | |
| 女 | 30 | 33.3 | 11 | 44.0 | 19 | 29.2 | |
| 既往病史 | 0.193b | ||||||
| 高血压 | 28 | 31.1 | 10 | 40.0 | 18 | 28.1 | |
| 糖尿病 | 5 | 5.6 | 3 | 12.0 | 2 | 3.1 | |
| 其他头颈部肿瘤 | 5 | 5.6 | 3 | 12.0 | 2 | 3.1 | |
| 是否吸烟 | |||||||
| 吸烟 | 35 | 38.9 | 9 | 24.0 | 26 | 40.0 | 0.727c |
| 不吸烟 | 55 | 61.1 | 16 | 76.0 | 39 | 60.0 | |
| 是否饮酒 | |||||||
| 饮酒 | 39 | 56.7 | 6 | 24.0 | 32 | 49.2 | 0.030c |
| 不饮酒 | 51 | 43.3 | 19 | 76.0 | 33 | 50.8 | |
| 肿瘤类型/例 | |||||||
| 扁桃体 | 76 | 84.4 | 22 | 88.0 | 54 | 83.1 | 0.567b |
| 舌根 | 9 | 10.0 | 2 | 8.0 | 7 | 10.8 | |
| 软腭 | 1 | 1.1 | 0 | 0 | 1 | 1.5 | |
| 咽侧壁 | 4 | 4.4 | 1 | 4.0 | 3 | 4.6 | |
| T stage | |||||||
| ypT0 | 7 | 7.8 | 1 | 4.0 | 6 | 9.2 | 0.09b |
| pT1 | 34 | 37.8 | 6 | 24.0 | 28 | 43.1 | |
| pT2 | 43 | 47.8 | 17 | 68.0 | 26 | 40.0 | |
| pT3 | 6 | 6.7 | 1 | 4.0 | 5 | 7.7 | |
| N stage | 0.185b | ||||||
| pN0 | 27 | 30.0 | 5 | 20.0 | 22 | 33.8 | |
| pN1 | 55 | 61.1 | 17 | 68.0 | 38 | 58.5 | |
| pN2 | 8 | 8.9 | 3 | 12.0 | 5 | 7.7 | |
| 病理分化 | |||||||
| 高分化 | 3 | 3.3 | 2 | 8.0 | 1 | 1.5 | 0.231b |
| 中分化 | 56 | 62.2 | 17 | 68.0 | 39 | 60.0 | |
| 低分化 | 18 | 20.0 | 4 | 16.0 | 14 | 21.5 | |
| 缺失 | 13 | 14.4 | 2 | 8.0 | 11 | 16.9 | |
| 辅助治疗 | 0.233b | ||||||
| 术前诱导 | 15 | 17.8 | 2 | 8.0 | 14 | 21.6 | |
| 术后放±化疗 | 34 | 37.8 | 10 | 40.0 | 24 | 36.9 | |