Skip to main content
Evidence-based Complementary and Alternative Medicine : eCAM logoLink to Evidence-based Complementary and Alternative Medicine : eCAM
. 2026 Feb 27;2026:9840453. doi: 10.1155/ecam/9840453

RETRACTION: Involvement of Heme Oxygenase‐1 Participates in Anti‐Inflammatory and Analgesic Effects of Aqueous Extract of Hibiscus taiwanensis

Evidence-Based Complementary and Alternative Medicine
PMCID: PMC12948226  PMID: 41769633

RETRACTION: S.‐L. Liu, J.‐S. Deng, C.‐S. Chiu, et al., “Involvement of Heme Oxygenase‐1 Participates in Anti‐Inflammatory and Analgesic Effects of Aqueous Extract of Hibiscus taiwanensis,” Evidence-Based Complementary and Alternative Medicine, vol. 2012 (2012). https://doi.org/10.1155/2012/132859.

The above article, published online on 21 June 2012 in Wiley Online Library (https://wileyonlinelibrary.com), has been retracted by John Wiley & Sons Ltd.

The retraction has been agreed following an investigation of the concerns raised by Actinopolyspora biskrensis on PubPeer [1], which identified several concerns related to multiple figures in the paper. More specifically,

Figure 5a: The COX‐2 and B‐Actin bands are identical after a horizontal stretch.

Figure 6a: The image of the control and Carr panels shares overlapping features with Figure 8a of [2] and 4a of [3].

As a result of the investigation, the data and conclusions of this article are considered unreliable.

The authors have been informed of this decision but did not provide a response.

References

  • 1. Actinopolyspora biskrensis, “Involvement of Heme Oxygenase-1 Participates in Anti-Inflammatory and Analgesic Effects of Aqueous Extract of Hibiscus taiwanensis,” PubPeer, June 2024. https://pubpeer.com/publications/010D5B150AD6ABE3F887569E0CFB55. [DOI] [PMC free article] [PubMed] [Retracted]
  • 2. Liao J.-C., Deng J.-S., Chiu C.-S. et al., Anti-Inflammatory Activities of Cinnamomum cassia Constituents In Vitro and In Vivo , Evidence-Based Complementary and Alternative Medicine. (2012) 2012, 10.1155/2012/429320, 2-s2.0-84859763499. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 3. Chang T.-N., Deng J.-S., Chang Y.-C. et al., Ameliorative Effects of Scopoletin from Crossostephium chinensis against Inflammation Pain and Its Mechanisms in Mice, Evidence-Based Complementary and Alternative Medicine. (2012) 2012, 10.1155/2012/595603, 2-s2.0-84867019397. [DOI] [PMC free article] [PubMed] [Google Scholar] [Retracted]

Articles from Evidence-based Complementary and Alternative Medicine : eCAM are provided here courtesy of Wiley

RESOURCES