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. 1994 Oct;87(10):594–595. doi: 10.1177/014107689408701009

Ginseng--a root just like a carrot?

A Wilkie 1, C Cordess 1
PMCID: PMC1294848  PMID: 7966106

Abstract

Ginseng has been used for thousands of years in the East as a 'tonic', and in recent years its use has extended to Western society. In the light of the current interest in complementary medicine, we summarize the effects and purported mechanisms of action of ginseng and present two vignettes of its use in relation to psychiatric patients, followed by a general discussion of the implications of the use of herbal products by these patients.

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Selected References

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  1. Benishin C. G., Lee R., Wang L. C., Liu H. J. Effects of ginsenoside Rb1 on central cholinergic metabolism. Pharmacology. 1991;42(4):223–229. doi: 10.1159/000138801. [DOI] [PubMed] [Google Scholar]
  2. Bittles A. H., Fulder S. J., Grant E. C., Nicholls M. R. The effect of ginseng on lifespan and stress responses in mice. Gerontology. 1979;25(3):125–131. doi: 10.1159/000212330. [DOI] [PubMed] [Google Scholar]
  3. Brekhman I. I., Dardymov I. V. New substances of plant origin which increase nonspecific resistance. Annu Rev Pharmacol. 1969;9:419–430. doi: 10.1146/annurev.pa.09.040169.002223. [DOI] [PubMed] [Google Scholar]
  4. Brenner N., Frank O. S., Knight E. Chronic nutmeg psychosis. J R Soc Med. 1993 Mar;86(3):179–180. doi: 10.1177/014107689308600326. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Filaretov A. A., Bogdanova T. S., Podvigina T. T., Bodganov A. I. Role of pituitary-adrenocortical system in body adaptation abilities. Exp Clin Endocrinol. 1988 Dec;92(2):129–136. doi: 10.1055/s-0029-1210793. [DOI] [PubMed] [Google Scholar]
  6. Fulder S. J. Ginseng and the hypothalamic-pituitary control of stress. Am J Chin Med. 1981 Summer;9(2):112–118. doi: 10.1142/s0192415x81000159. [DOI] [PubMed] [Google Scholar]
  7. Godlee F. Medicinal plants: another man's poison. BMJ. 1992 Dec 19;305(6868):1583–1585. doi: 10.1136/bmj.305.6868.1583. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Hassiotis A., Taylor J. Psychotic illness following 'mabi bark tea' consumption. Br J Psychiatry. 1992 Sep;161:404–407. doi: 10.1192/bjp.161.3.404. [DOI] [PubMed] [Google Scholar]
  9. Hiai S., Yokoyama H., Oura H., Yano S. Stimulation of pituitary-adrenocortical system by ginseng saponin. Endocrinol Jpn. 1979 Dec;26(6):661–665. doi: 10.1507/endocrj1954.26.661. [DOI] [PubMed] [Google Scholar]
  10. Lee S. P., Honda K., Rhee Y. H., Inoué S. Chronic intake of panax ginseng extract stabilizes sleep and wakefulness in food-deprived rats. Neurosci Lett. 1990 Mar 26;111(1-2):217–221. doi: 10.1016/0304-3940(90)90371-f. [DOI] [PubMed] [Google Scholar]
  11. Pantelis C., Hindler C. G., Taylor J. C. Use and abuse of khat (Catha edulis): a review of the distribution, pharmacology, side effects and a description of psychosis attributed to khat chewing. Psychol Med. 1989 Aug;19(3):657–668. doi: 10.1017/s0033291700024259. [DOI] [PubMed] [Google Scholar]
  12. Rottanburg D., Robins A. H., Ben-Arie O., Teggin A., Elk R. Cannabis-associated psychosis with hypomanic features. Lancet. 1982 Dec 18;2(8312):1364–1366. doi: 10.1016/s0140-6736(82)91270-3. [DOI] [PubMed] [Google Scholar]
  13. Saito H., Tsuchiya M., Naka S., Takagi K. Effects of Panax Ginseng root on conditioned avoidance response in rats. Jpn J Pharmacol. 1977 Aug;27(4):509–516. doi: 10.1254/jjp.27.509. [DOI] [PubMed] [Google Scholar]
  14. Watanabe H., Ohta H., Imamura L., Asakura W., Matoba Y., Matsumoto K. Effect of Panax ginseng on age-related changes in the spontaneous motor activity and dopaminergic nervous system in the rat. Jpn J Pharmacol. 1991 Jan;55(1):51–56. doi: 10.1254/jjp.55.51. [DOI] [PubMed] [Google Scholar]
  15. Yoshimura H., Watanabe K., Ogawa N. Acute and chronic effects of ginseng saponins on maternal aggression in mice. Eur J Pharmacol. 1988 Jun 10;150(3):319–324. doi: 10.1016/0014-2999(88)90013-1. [DOI] [PubMed] [Google Scholar]
  16. Zaslove M. O., Russell R. L., Ross E. Effect of caffeine intake on psychotic in-patients. Br J Psychiatry. 1991 Oct;159:565–567. doi: 10.1192/bjp.159.4.565. [DOI] [PubMed] [Google Scholar]

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