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. 1994 Oct;87(10):608–609. doi: 10.1177/014107689408701015

Glucose tolerance and ageing.

R W Stout 1
PMCID: PMC1294853  PMID: 7966111

Abstract

Hyperglycaemia, impaired glucose tolerance and noninsulin dependent diabetes become progressively more common with advancing age. The mechanism is insensitivity to the actions of insulin at the postreceptor level. Inadequate secretion of insulin and decreased hepatic sensitivity to insulin's action in suppressing glucose output also occur. The age-related changes may be made worse by obesity, renal failure or the ingestion of certain drugs, or may be lessened by increased physical activity.

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Selected References

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