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. 1995 Jun;88(6):339P–341P.

Hypersecretion of luteinizing hormone in the polycystic ovary syndrome and a novel hormone 'gonadotrophin surge attenuating factor'.

A H Balen 1
PMCID: PMC1295241  PMID: 7629766

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Adashi E. Y., Hsueh A. J., Yen S. S. Insulin enhancement of luteinizing hormone and follicle-stimulating hormone release by cultured pituitary cells. Endocrinology. 1981 Apr;108(4):1441–1449. doi: 10.1210/endo-108-4-1441. [DOI] [PubMed] [Google Scholar]
  2. Baird D. T., Corker C. S., Davidson D. W., Hunter W. M., Michie E. A., Van Look P. F. Pituitary-ovarian relationships in polycystic ovary syndrome. J Clin Endocrinol Metab. 1977 Oct;45(4):798–801. doi: 10.1210/jcem-45-4-798. [DOI] [PubMed] [Google Scholar]
  3. Balen A. H., Jacobs H. S. Gonadotrophin surge attenuating factor: a missing link in the control of LH secretion? Clin Endocrinol (Oxf) 1991 Nov;35(5):399–402. doi: 10.1111/j.1365-2265.1991.tb03555.x. [DOI] [PubMed] [Google Scholar]
  4. Balen A. H., Tan S. L., MacDougall J., Jacobs H. S. Miscarriage rates following in-vitro fertilization are increased in women with polycystic ovaries and reduced by pituitary desensitization with buserelin. Hum Reprod. 1993 Jun;8(6):959–964. doi: 10.1093/oxfordjournals.humrep.a138174. [DOI] [PubMed] [Google Scholar]
  5. Buckler H. M., McLachlan R. I., MacLachlan V. B., Healy D. L., Burger H. G. Serum inhibin levels in polycystic ovary syndrome: basal levels and response to luteinizing hormone-releasing hormone agonist and exogenous gonadotropin administration. J Clin Endocrinol Metab. 1988 Apr;66(4):798–803. doi: 10.1210/jcem-66-4-798. [DOI] [PubMed] [Google Scholar]
  6. Burger C. W., Korsen T., van Kessel H., van Dop P. A., Caron F. J., Schoemaker J. Pulsatile luteinizing hormone patterns in the follicular phase of the menstrual cycle, polycystic ovarian disease (PCOD) and non-PCOD secondary amenorrhea. J Clin Endocrinol Metab. 1985 Dec;61(6):1126–1132. doi: 10.1210/jcem-61-6-1126. [DOI] [PubMed] [Google Scholar]
  7. Chang R. J., Mandel F. P., Lu J. K., Judd H. L. Enhanced disparity of gonadotropin secretion by estrone in women with polycystic ovarian disease. J Clin Endocrinol Metab. 1982 Mar;54(3):490–494. doi: 10.1210/jcem-54-3-490. [DOI] [PubMed] [Google Scholar]
  8. Conway G. S., Honour J. W., Jacobs H. S. Heterogeneity of the polycystic ovary syndrome: clinical, endocrine and ultrasound features in 556 patients. Clin Endocrinol (Oxf) 1989 Apr;30(4):459–470. doi: 10.1111/j.1365-2265.1989.tb00446.x. [DOI] [PubMed] [Google Scholar]
  9. Gadir A. A., Khatim M. S., Mowafi R. S., Alnaser H. M., Alzaid H. G., Shaw R. W. Hormonal changes in patients with polycystic ovarian disease after ovarian electrocautery or pituitary desensitization. Clin Endocrinol (Oxf) 1990 Jun;32(6):749–754. doi: 10.1111/j.1365-2265.1990.tb00921.x. [DOI] [PubMed] [Google Scholar]
  10. Kazer R. R., Kessel B., Yen S. S. Circulating luteinizing hormone pulse frequency in women with polycystic ovary syndrome. J Clin Endocrinol Metab. 1987 Aug;65(2):233–236. doi: 10.1210/jcem-65-2-233. [DOI] [PubMed] [Google Scholar]
  11. Messinis I. E., Templeton A., Baird D. T. Endogenous luteinizing hormone surge during superovulation induction with sequential use of clomiphene citrate and pulsatile human menopausal gonadotropin. J Clin Endocrinol Metab. 1985 Dec;61(6):1076–1080. doi: 10.1210/jcem-61-6-1076. [DOI] [PubMed] [Google Scholar]
  12. Murdoch A. P., Diggle P. J., White M. C., Kendall-Taylor P., Dunlop W. LH in polycystic ovary syndrome: reproducibility and pulsatile secretion. J Endocrinol. 1989 Apr;121(1):185–191. doi: 10.1677/joe.0.1210185. [DOI] [PubMed] [Google Scholar]
  13. Polson D. W., Adams J., Wadsworth J., Franks S. Polycystic ovaries--a common finding in normal women. Lancet. 1988 Apr 16;1(8590):870–872. doi: 10.1016/s0140-6736(88)91612-1. [DOI] [PubMed] [Google Scholar]
  14. Rebar R., Judd H. L., Yen S. S., Rakoff J., Vandenberg G., Naftolin F. Characterization of the inappropriate gonadotropin secretion in polycystic ovary syndrome. J Clin Invest. 1976 May;57(5):1320–1329. doi: 10.1172/JCI108400. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Regan L., Owen E. J., Jacobs H. S. Hypersecretion of luteinising hormone, infertility, and miscarriage. Lancet. 1990 Nov 10;336(8724):1141–1144. doi: 10.1016/0140-6736(90)92765-a. [DOI] [PubMed] [Google Scholar]
  16. Rossmanith W. G., Keckstein J., Spatzier K., Lauritzen C. The impact of ovarian laser surgery on the gonadotrophin secretion in women with polycystic ovarian disease. Clin Endocrinol (Oxf) 1991 Mar;34(3):223–230. doi: 10.1111/j.1365-2265.1991.tb00298.x. [DOI] [PubMed] [Google Scholar]
  17. Sopelak V. M., Hodgen G. D. Blockade of the estrogen-induced luteinizing hormone surge in monkeys: a nonsteroidal, antigenic factor in porcine follicular fluid. Fertil Steril. 1984 Jan;41(1):108–113. doi: 10.1016/s0015-0282(16)47550-3. [DOI] [PubMed] [Google Scholar]
  18. Spinder T., Spijkstra J. J., van den Tweel J. G., Burger C. W., van Kessel H., Hompes P. G., Gooren L. J. The effects of long term testosterone administration on pulsatile luteinizing hormone secretion and on ovarian histology in eugonadal female to male transsexual subjects. J Clin Endocrinol Metab. 1989 Jul;69(1):151–157. doi: 10.1210/jcem-69-1-151. [DOI] [PubMed] [Google Scholar]
  19. Stanger J. D., Yovich J. L. Reduced in-vitro fertilization of human oocytes from patients with raised basal luteinizing hormone levels during the follicular phase. Br J Obstet Gynaecol. 1985 Apr;92(4):385–393. doi: 10.1111/j.1471-0528.1985.tb01113.x. [DOI] [PubMed] [Google Scholar]
  20. Venturoli S., Porcu E., Fabbri R., Magrini O., Gammi L., Paradisi R., Forcacci M., Bolzani R., Flamigni C. Episodic pulsatile secretion of FSH, LH, prolactin, oestradiol, oestrone, and LH circadian variations in polycystic ovary syndrome. Clin Endocrinol (Oxf) 1988 Jan;28(1):93–107. doi: 10.1111/j.1365-2265.1988.tb01208.x. [DOI] [PubMed] [Google Scholar]
  21. Wang C. F., Lasley B. L., Lein A., Yen S. S. The functional changes of the pituitary gonadotrophs during the menstrual cycle. J Clin Endocrinol Metab. 1976 Apr;42(4):718–728. doi: 10.1210/jcem-42-4-718. [DOI] [PubMed] [Google Scholar]

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