Skip to main content
Journal of the Royal Society of Medicine logoLink to Journal of the Royal Society of Medicine
. 1996 Jul;89(7):401–402.

Seroprevalence of hepatitis B and C virus in two institutions caring for mentally handicapped adults.

M E Cramp 1, H C Grundy 1, R M Perinpanayagam 1, D E Barnado 1
PMCID: PMC1295856  PMID: 8774540

Abstract

Hepatitis B virus infection is common in institutions caring for the mentally handicapped. Hepatitis B virus and hepatitis C virus share routes of transmission but the prevalence of hepatitis C virus infection in this population is unknown. We have tested 101 patients from two institutions in South-East England caring for adults with mental handicap for the presence of hepatitis C antibody, hepatitis B core antibody, and if necessary hepatitis B surface antigen. None tested positive for hepatitis C antibody, but 43 had hepatitis B core antibody of whom 14 were chronic carriers positive for hepatitis B surface antigen. Unlike hepatitis B virus, hepatitis C virus infection appears to be uncommon in UK institutions.

Full text

PDF
401

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Alter M. J. Epidemiology of hepatitis C in the West. Semin Liver Dis. 1995 Feb;15(1):5–14. doi: 10.1055/s-2007-1007259. [DOI] [PubMed] [Google Scholar]
  2. Chaudhary R. K., Perry E., Hicks F., MacLean C., Morbey M. Hepatitis B and C infection in an institution for the developmentally handicapped. N Engl J Med. 1992 Dec 31;327(27):1953–1953. doi: 10.1056/NEJM199212313272713. [DOI] [PubMed] [Google Scholar]
  3. Cunningham S. J., Cunningham R., Izmeth M. G., Baker B., Hart C. A. Seroprevalence of hepatitis B and C in a Merseyside hospital for the mentally handicapped. Epidemiol Infect. 1994 Feb;112(1):195–200. doi: 10.1017/s0950268800057563. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Dusheiko G. M., Smith M., Scheuer P. J. Hepatitis C virus transmitted by human bite. Lancet. 1990 Aug 25;336(8713):503–504. doi: 10.1016/0140-6736(90)92049-n. [DOI] [PubMed] [Google Scholar]
  5. Esteban J. I., Esteban R., Viladomiu L., López-Talavera J. C., González A., Hernández J. M., Roget M., Vargas V., Genescà J., Buti M. Hepatitis C virus antibodies among risk groups in Spain. Lancet. 1989 Aug 5;2(8658):294–297. doi: 10.1016/s0140-6736(89)90485-6. [DOI] [PubMed] [Google Scholar]
  6. Hollinger F. B., Lin H. J. Community-acquired hepatitis C virus infection. Gastroenterology. 1992 Apr;102(4 Pt 1):1426–1429. doi: 10.1016/0016-5085(92)90791-v. [DOI] [PubMed] [Google Scholar]
  7. Idéo G., Bellati G., Pedraglio E., Bottelli R., Donzelli T., Putignano G. Intrafamilial transmission of hepatitis C virus. Lancet. 1990 Feb 10;335(8685):353–353. doi: 10.1016/0140-6736(90)90636-j. [DOI] [PubMed] [Google Scholar]
  8. Kingham J. G., McGuire M., Paine D. H., Wright R. Hepatitis B in a hospital for the mentally subnormal in southern England. Br Med J. 1978 Aug 26;2(6137):594–596. doi: 10.1136/bmj.2.6137.594. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Krugman S., Overby L. R., Mushahwar I. K., Ling C. M., Frösner G. G., Deinhardt F. Viral hepatitis, type B. Studies on natural history and prevention re-examined. N Engl J Med. 1979 Jan 18;300(3):101–106. doi: 10.1056/NEJM197901183000301. [DOI] [PubMed] [Google Scholar]
  10. Levinson W. M., Wormser G. P., Forseter G., Calmann M., O'Brien T. A. Hepatitis C virus seroprevalence in the developmentally disabled. Arch Intern Med. 1992 Nov;152(11):2309–2311. [PubMed] [Google Scholar]
  11. Martínez J. L., del Hierro J., Camarero A., Medarde A., López M. T., Latasa J. Estudio de la infección por virus de la hepatitis C en diferentes grupos de riesgo y en donantes de sangre. Enferm Infecc Microbiol Clin. 1991 Jun-Jul;9(6):345–350. [PubMed] [Google Scholar]
  12. Mortimer P. P., Cohen B. J., Litton P. A., Vandervelde E. M., Bassendine M. F., Brind A. M., Hambling M. H. Hepatitis C virus antibody. Lancet. 1989 Sep 30;2(8666):798–798. doi: 10.1016/s0140-6736(89)90854-4. [DOI] [PubMed] [Google Scholar]
  13. Mutimer D. J., Harrison R. F., O'Donnell K. B., Shaw J., Martin B. A., Atrah H., Ala F. A., Skidmore S., Hubscher S. G., Neuberger J. M. Hepatitis C virus infection in the asymptomatic British blood donor. J Viral Hepat. 1995;2(1):47–53. doi: 10.1111/j.1365-2893.1995.tb00071.x. [DOI] [PubMed] [Google Scholar]
  14. Szmuness W., Prince A. M., Etling G. F., Pick R. Development and distribution of hemagglutinating antibody against the hepatitis B antigen in institutionalized populations. J Infect Dis. 1972 Nov;126(5):498–506. doi: 10.1093/infdis/126.5.498. [DOI] [PubMed] [Google Scholar]
  15. Yano M. Advances in hepatitis C: sero-epidemiology and natural history. J Gastroenterol Hepatol. 1992 Sep-Oct;7(5):549–550. doi: 10.1111/j.1440-1746.1992.tb01036.x. [DOI] [PubMed] [Google Scholar]

Articles from Journal of the Royal Society of Medicine are provided here courtesy of Royal Society of Medicine Press

RESOURCES