OBJECTIVE
This video presentation demonstrates an evidence-based approach on the surgical steps of a laparoscopic myomectomy for a multi-fibroid uterus.[Video]
DESIGN
We are presenting a video demonstrating the steps of the surgery and the technique with narration.
PATIENT
We are presenting a case of a 34-year-old nulliparous patient with a history of primary infertility. The patient had a history of three unsuccessful embryo transfers. She was otherwise medically fit and well and had no previous surgeries. Her magnetic resonance imaging pelvis showed three uterine fibroids. The dominant fibroid was 6.5 cm × 6.9 cm in size, arising from the posterior wall of the uterus. There were two intramural fibroids at the fundal area with the largest measuring 3.1 cm × 3.3 cm [Figure 1]. The evidence for myomectomy before In-Vitro-Fertilisation (IVF) treatment was discussed, and the patient was counseled that surgery for intramural fibroids, not distorting the endometrial cavity, might not improve the chance of live birth.[1,2] However, given her history of recurrent implantation failure and the patient’s wish, it was agreed to proceed to surgery.
Figure 1.

Pelvic magnetic resonance imaging demonstrating the fibroids/Traction-counter traction maneuver with myomectomy screw
http://www.apagemit.com/page/video/show.aspx?num=1370&kind=2&page=1
INTERVENTIONS
Laparoscopic myomectomy is safe and efficient, offering a quicker recovery, comparing to open approach, without increasing the risk of complications.[3]
Following standard insertion of a 10 mm intraumbilical, a 5 mm right iliac fossa, a 10 mm and a 5 mm left iliac fossa laparoscopic ports, diluted argipressin was injected beneath the fibroid pseudocapsules. The uterine blanching due to vasoconstriction is observed, achieving adequate hemostasis.[4,5] Uterine artery ligation is not needed in this case.[6] An ultrasonic scalpel is used for the fibroid enucleation, aiming to reduce blood loss.[7] Careful dissection is employed to avoid breaching the endometrial cavity. Three fibroids are enucleated with traction and counter-traction maneuvers through two uterine incisions, using a myomectomy screw and claw graspers [Figure 1]. The use of barbed sutures to close the uterine bed facilitates a shorter operating time and reduces blood loss.[8] In-bag power morcellation (LiNA Xcise™ and Espiner ECO-T Containment Bag) through the left iliac fossa, incision is used to retrieve the specimens reducing the risk of developing parasitic fibroids[9] and offering protection in the rare event of an undiagnosed sarcoma.[10,11,12,13] Hyaluronic acid gel is applied on the uterine incisions to prevent intra-abdominal adhesions.[14,15,16]
Three fibroids were removed with a total weight of 154 g. The procedure lasted approximately 2 hours. The patient was discharged the next day. There is insufficient data to advise a minimal time interval between myomectomy and conception.[17] The patient was advised to delay conception for a minimum of 3 months.
CONCLUSION
This video emphasizes that laparoscopic myomectomy is a safe and effective option for women who wish to retain fertility, with advantages such as shorter recovery time, less pain, and better cosmetic results than open surgery. Laparoscopic myomectomy surgical and fertility outcomes are comparative with robotic and superior to abdominal myomectomy.[18] The use of vasoconstrictive agents, ultrasonic scalpel, myoma screw, barbed sutures, and in-bag power morcellation is recommended to facilitate a successful procedure.
Ethics statement
This study was conducted in accordance with the ethical principles outlined in the Declaration of Helsinki and its amendments. The authors certify that they have obtained all appropriate patient consent forms. In the form, the patient has given her consent for her images and other clinical information to be reported in the journal. The patient understands that her name and initials will not be published and due efforts will be made to conceal identity, but anonymity cannot be guaranteed.
Author contributions
D.M., T.M. and N.T. Conceived the idea and jointly performed the surgery. All authors contributed to the video editing and writing the manuscript.
Data availability statement
Data sharing is not applicable to this article as no datasets were generated or analyzed during the current study.
Conflicts of interest
There are no conflicts of interest.
Video Available on: https://journals.lww.com/gmit
Funding Statement
Nil.
REFERENCES
- 1.Pritts EA, Parker WH, Olive DL. Fibroids and infertility: An updated systematic review of the evidence. Fertil Steril. 2009;91:1215–23. doi: 10.1016/j.fertnstert.2008.01.051. [DOI] [PubMed] [Google Scholar]
- 2.Sunkara SK, Khairy M, El-Toukhy T, Khalaf Y, Coomarasamy A. The effect of intramural fibroids without uterine cavity involvement on the outcome of IVF treatment: A systematic review and meta-analysis. Hum Reprod. 2010;25:418–29. doi: 10.1093/humrep/dep396. [DOI] [PubMed] [Google Scholar]
- 3.Paredes JS, Lee CL, Chua PT. Myomectomy: Choosing the surgical approach – A systematic review. Gynecol Minim Invasive Ther. 2024;13:146–53. doi: 10.4103/gmit.gmit_152_23. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 4.Alomar O, Abu-Zaid A, Jamjoom MZ, Almubarki AA, Alsehaimi SO, Alabdrabalamir S, et al. Prophylactic vasopressin to reduce intraoperative blood loss and associated morbidities during myomectomy: A systematic review and meta-analysis of 11 controlled trials. J Gynecol Obstet Hum Reprod. 2022;51:102485. doi: 10.1016/j.jogoh.2022.102485. [DOI] [PubMed] [Google Scholar]
- 5.Sleiman Z, Baba RE, Garzon S, Khazaka A. The significant risk factors of intra-operative hemorrhage during laparoscopic myomectomy: A systematic review. Gynecol Minim Invasive Ther. 2020;9:6–12. doi: 10.4103/GMIT.GMIT_21_19. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 6.Ai G, Huang W, Yang W, Liu J, Luo N, Guo J, et al. Avideo article: The laparoscopic uterine artery occlusion in combination with myomectomy for uterine myoma. Gynecol Minim Invasive Ther. 2022;11:114–5. doi: 10.4103/GMIT.GMIT_10_21. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 7.Lin J, Zhang X, Xu K. Application of ultrasonic scalpel in gynecologic operative laparoscopy. Chin Med J (Engl) 2001;114:1283–5. [PubMed] [Google Scholar]
- 8.Kathopoulis N, Prodromidou A, Douligeris A, Diakosavvas M, Zacharakis D, Kypriotis K, et al. Barbed sutures compared with conventional sutures during laparoscopic myomectomy: A systematic review and meta-analysis. Obstet Gynecol. 2024;144:e81–100. doi: 10.1097/AOG.0000000000005695. [DOI] [PubMed] [Google Scholar]
- 9.Pai AH, Yen CF, Lin SL. Parasitic leiomyoma. Gynecol Minim Invasive Ther. 2020;9:108–9. doi: 10.4103/GMIT.GMIT_35_20. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 10.Giannini A, Golia D’Augè T, Bogani G, Laganà AS, Chiantera V, Vizza E, et al. Uterine sarcomas: A critical review of the literature. Eur J Obstet Gynecol Reprod Biol. 2023;287:166–70. doi: 10.1016/j.ejogrb.2023.06.016. [DOI] [PubMed] [Google Scholar]
- 11.Brower V. FDA considers restricting or banning laparoscopic morcellation. J Natl Cancer Inst. 2014;106:dju339. doi: 10.1093/jnci/dju339. [DOI] [PubMed] [Google Scholar]
- 12.Adelman MR. The morcellation debate: The history and the science. Clin Obstet Gynecol. 2015;58:710–7. doi: 10.1097/GRF.0000000000000150. [DOI] [PubMed] [Google Scholar]
- 13.ACOG committee opinion no. 770: Uterine morcellation for presumed leiomyomas. Obstet Gynecol. 2019;133:e238–48. doi: 10.1097/AOG.0000000000003126. [DOI] [PubMed] [Google Scholar]
- 14.Farag S, Padilla PF, Smith KA, Sprague ML, Zimberg SE. Management, prevention, and sequelae of adhesions in women undergoing laparoscopic gynecologic surgery: A systematic review. J Minim Invasive Gynecol. 2018;25:1194–216. doi: 10.1016/j.jmig.2017.12.010. [DOI] [PubMed] [Google Scholar]
- 15.Mais V, Bracco GL, Litta P, Gargiulo T, Melis GB. Reduction of postoperative adhesions with an auto-crosslinked hyaluronan gel in gynaecological laparoscopic surgery: A blinded, controlled, randomized, multicentre study. Hum Reprod. 2006;21:1248–54. doi: 10.1093/humrep/dei488. [DOI] [PubMed] [Google Scholar]
- 16.Practice Committee of the American Society for Reproductive Medicine in Collaboration with the Society of Reproductive Surgeons Electronic Address: Asrm@asrmorg, Practice Committee of the American Society for Reproductive Medicine in Collaboration with the Society of Reproductive Surgeons. Postoperative adhesions in gynecologic surgery: A committee opinion. Fertil Steril. 2019;112:458–63. [Google Scholar]
- 17.Margueritte F, Adam C, Fauconnier A, Gauthier T. Time to conceive after myomectomy: Should we advise a minimum time interval? A systematic review. Reprod Biomed Online. 2021;43:543–52. doi: 10.1016/j.rbmo.2021.05.016. [DOI] [PubMed] [Google Scholar]
- 18.Tsakos E, Xydias EM, Ziogas AC, Sorrentino F, Nappi L, Vlachos N, et al. Multi-port robotic-assisted laparoscopic myomectomy: A systematic review and meta-analysis of comparative clinical and fertility outcomes. J Clin Med. 2023;12:4134. doi: 10.3390/jcm12124134. [DOI] [PMC free article] [PubMed] [Google Scholar]
Associated Data
This section collects any data citations, data availability statements, or supplementary materials included in this article.
Supplementary Materials
Data Availability Statement
Data sharing is not applicable to this article as no datasets were generated or analyzed during the current study.
