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Acta Endocrinologica (Bucharest) logoLink to Acta Endocrinologica (Bucharest)
. 2025 Jan-Mar;21(1):152. doi: 10.4183/aeb.2025.152

DYNAMIC ENDOCRINE TESTING, 5TH EDITION

Reviewed by: Gratiela Bratu MD, PhD student 1
Andreas Schäffler, editor. Dynamic Endocrine Testing. 2025. Springer-Verlag GmbH. 1-378. ISBN: 978-3-662-70260-4.
PMCID: PMC12966831

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Publisher: Springer-Verlag GmbH

Editor: Andreas Schäffler

Language: English

Year: 2025

ISBN: 978-3-662-70259-8

E-ISBN: 978-3-662-70260-4

No. of pages: 378

Dynamic Endocrine Testing, edited by Andreas Schäffler, is a practice-oriented reference that fills a long-standing gap in clinical endocrinology. Available in English in its thoroughly revised 5th edition, this volume offers a systematic approach to functional endocrine diagnostics across the full spectrum of endocrinology, diabetology, and metabolism.

Unlike other textbooks, this work focuses explicitly on dynamic testing, integrating physiological principles with step-by-step guidance on indications, contraindications, patient preparation, test execution, and interpretation of results. Each test is presented in a structured format, enriched with clearly defined cut-off values, reference ranges, and conversion factors, including adaptations for age, sex, body composition, and clinical context. Particularly valuable are the dedicated sections on pitfalls and practical tips, reflecting extensive real-world experience and addressing common sources of diagnostic error.

The volume is structured in a practice-oriented manner, with major sections covering preanalytical aspects of hormone testing, metabolic pathways, and the systematic evaluation of all major endocrine axes, including thyroid, parathyroid, adrenal, pituitary, gonadal, and hypothalamic function. Additional chapters address genetic diagnostics, endocrine tumors, autoimmunity, imaging techniques, and digital tools such as continuous glucose monitoring, offering a clinically relevant overview of modern dynamic endocrine and diabetes diagnostics.

The 5th edition incorporates major updates aligned with recent WHO classification of 2022, advances in immunoassays, and emerging diagnostic tools such as copeptin measurement, calcitonin and metyrapone suppression test, macimorelin testing, and digital parameters derived from continuous glucose monitoring. With its comprehensiveness, clarity, and strong clinical orientation, Dynamic Endocrine Testing is an indispensable resource for endocrinologists, internists, and trainees seeking to optimize diagnostic accuracy and translate complex hormonal testing into confident clinical decision-making.


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