Abstract
Mastalgia is a common condition in women of reproductive years. We have assessed the long-term course in patients with severe mastalgia by distributing a postal questionnaire to 212 patients previously studied in 1983 who had attended the mastalgia clinic at the University Hospital of Wales, Cardiff. 175 patients (83%) responded, with an original diagnosis of cyclical mastalgia (CM) in 120 and non-cyclical mastalgia (NCM) in 55. The median age of onset of breast pain was 36 years (range 12-63 years). The average duration of pain was long (median 12 years), especially if it started in the second or third decade of life. Pain persisted in 68 (57%) of CM and 35 (64%) of NCM patients. In CM patients resolution was commonly associated with a 'hormonal' event, notably the menopause; in NCM patients it more often seemed to be spontaneous. Severe mastalgia ran a chronic relapsing course often requiring repeated drug treatments.
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Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Bishop H. M., Blamey R. W. A suggested classification of breast pain. Postgrad Med J. 1979;55 (Suppl 5):59–60. [PubMed] [Google Scholar]
- Griffith C. D., Dowle C. S., Hinton C. P., Blamey R. W. The breast pain clinic: a rational approach to classification and treatment of breast pain. Postgrad Med J. 1987 Jul;63(741):547–549. doi: 10.1136/pgmj.63.741.547. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Harrison B. J., Maddox P. R., Mansel R. E. Maintenance therapy of cyclical mastalgia using low-dose danazol. J R Coll Surg Edinb. 1989 Apr;34(2):79–81. [PubMed] [Google Scholar]
- Maddox P. R., Harrison B. J., Mansel R. E., Hughes L. E. Non-cyclical mastalgia: an improved classification and treatment. Br J Surg. 1989 Sep;76(9):901–904. doi: 10.1002/bjs.1800760909. [DOI] [PubMed] [Google Scholar]
- Oldenhave A., Jaszmann L. J., Everaerd W. T., Haspels A. A. Hysterectomized women with ovarian conservation report more severe climacteric complaints than do normal climacteric women of similar age. Am J Obstet Gynecol. 1993 Mar;168(3 Pt 1):765–771. doi: 10.1016/s0002-9378(12)90816-9. [DOI] [PubMed] [Google Scholar]
- Parker M., Bosscher J., Barnhill D., Park R. Ovarian management during radical hysterectomy in the premenopausal patient. Obstet Gynecol. 1993 Aug;82(2):187–190. [PubMed] [Google Scholar]
- Preece P. E., Mansel R. E., Bolton P. M., Hughes L. M., Baum M., Gravelle I. H. Clinical syndromes of mastalgia. Lancet. 1976 Sep 25;2(7987):670–673. doi: 10.1016/s0140-6736(76)92477-6. [DOI] [PubMed] [Google Scholar]
- Pye J. K., Mansel R. E., Hughes L. E. Clinical experience of drug treatments for mastalgia. Lancet. 1985 Aug 17;2(8451):373–377. doi: 10.1016/s0140-6736(85)92506-1. [DOI] [PubMed] [Google Scholar]
- Wisbey J. R., Kumar S., Mansel R. E., Peece P. E., Pye J. K., Hughes L. E. Natural history of breast pain. Lancet. 1983 Sep 17;2(8351):672–674. doi: 10.1016/s0140-6736(83)92543-6. [DOI] [PubMed] [Google Scholar]