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. 2026 Mar 9;21(3):e0344462. doi: 10.1371/journal.pone.0344462

Correction: Methionine-Restricted C57BL/6J Mice Are Resistant to Diet-Induced Obesity and Insulin Resistance but Have Low Bone Density

Gene P Ables, Carmen E Perrone, David Orentreich, Norman Orentreich
PMCID: PMC12970924  PMID: 41801811

There is an error in the Figs 1 and S1. The panel A is incorrect. The range of the y-axis should have not been “0-100” but “0-400”. Please see the correct Figs 1 and S1 here.

Fig 1. MR mice on HFD have lower body weight gain despite increased energy intake.

Fig 1

(A) Cumulative food intake was measured on HFD mice twice a week for 99 days. (B) Body weights (BW) were measured on HFD mice twice a week for 99 days. (C) Body weight gain was the difference between the weights at the beginning and at the end of the study. (D) Energy intake was calculated based on the average daily energy (kcal) intake per gram body weight. (E) Absorption efficiency was estimated based on the amount of food intake and fecal output within a 24 h period as described in the Methods section. Data is presented as the mean ± SD of 8 mice per treatment group and analyzed by Two-way ANOVA followed by Bonferroni post-tests (A and B) or Student’s unpaired t-test (C–E). *p < 0.05, ***p < 0.001.

Supporting information

S1 Fig. MR mice on LFD have lower body weight gain despite increased energy intake.

(A) Cumulative food intake was measured on LFD mice twice a week for 99 days. (B) Body weights (BW) were measured on HFD mice twice a week for 99 days. (C) Body weight gain was the difference between the weights at the beginning and at the end of the study. (D) Energy intake was calculated based on the average daily energy (kcal) intake per gram body weight. (E) Absorption efficiency was estimated based on the amount of food intake and fecal output within a 24 h period as described in the Methods section. Data is presented as the mean ± SD of 8 mice per treatment group and analyzed by Two-way ANOVA followed by Bonferroni post-tests (A and B) or Student’s unpaired t-test (C–E). *p < 0.05, ***p < 0.001.

(TIFF)

Reference

  • 1.Ables GP, Perrone CE, Orentreich D, Orentreich N. Methionine-restricted C57BL/6J mice are resistant to diet-induced obesity and insulin resistance but have low bone density. PLoS One. 2012;7(12):e51357. doi: 10.1371/journal.pone.0051357 [DOI] [PMC free article] [PubMed] [Google Scholar]

Associated Data

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Supplementary Materials

S1 Fig. MR mice on LFD have lower body weight gain despite increased energy intake.

(A) Cumulative food intake was measured on LFD mice twice a week for 99 days. (B) Body weights (BW) were measured on HFD mice twice a week for 99 days. (C) Body weight gain was the difference between the weights at the beginning and at the end of the study. (D) Energy intake was calculated based on the average daily energy (kcal) intake per gram body weight. (E) Absorption efficiency was estimated based on the amount of food intake and fecal output within a 24 h period as described in the Methods section. Data is presented as the mean ± SD of 8 mice per treatment group and analyzed by Two-way ANOVA followed by Bonferroni post-tests (A and B) or Student’s unpaired t-test (C–E). *p < 0.05, ***p < 0.001.

(TIFF)


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