Rogler CE, Bebawee R, Matarlo J, Locker J, Pattamanuch N, Gupta S, Rogler LE. Triple staining including FOXA2 identifies stem cell lineages undergoing hepatic and biliary differentiation in cirrhotic human liver. J Histochem Cytochem. 2017;65(1):33-46. doi:10.1369/0022155416675153
The authors of the above-mentioned article were contacted regarding potential image duplication. The concerns relate to Figure 2A and the Figure 6 legend. The authors have provided the following clarifications regarding Figure 2A, and the legend of Figure 6 has been updated to include the following statement: “Panel B is an enlarged area from Fig. 2B.”
Figure 2A.
A small region of image duplication appears in the far corner of Figure 2A. The duplicated area is minimal, and its complete removal would not affect interpretation of the image. Upon review of the originally submitted and peer-reviewed figure, no duplication artifact was present, suggesting that the issue may have occurred during revision or production of the final paper. The duplication in the published version is minor and does not affect the information conveyed by this panel or the presentation of the findings.
Figure 6.
(A) Low magnification of a stem/progenitor micro-niche supporting both hepatocytic differentiation to the left (brown = FOXA2, blue = HepPar1) and bile ductular differentiation to the right (red-cytokeratin 19 [CK19]). Note mixtures of cells differentiating in either direction extending out from the center of micro-niche. (B) and (C) Two additional examples of micro-niches with oval cell proliferation and differentiation toward hepatocytic or bile ductular differentiation. Same color scheme with slightly different color intensities. Panel B is an enlarged area from Fig. 2B. Scale bar: B = 100u; C = 10u.