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. 1998;96:691–720.

A randomized, controlled trial of varying radiation doses in the treatment of choroidal melanoma.

E S Gragoudas
PMCID: PMC1298412  PMID: 10360306

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Selected References

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  1. Abramson D. H., Servodidio C. A., McCormick B., Fass D., Zang E. Changes in height of choroidal melanomas after plaque therapy. Br J Ophthalmol. 1990 Jun;74(6):359–362. doi: 10.1136/bjo.74.6.359. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Adams K. S., Abramson D. H., Ellsworth R. M., Haik B. G., Bedford M., Packer S., Seddon J., Albert D., Polivogianis L. Cobalt plaque versus enucleation for uveal melanoma: comparison of survival rates. Br J Ophthalmol. 1988 Jul;72(7):494–497. doi: 10.1136/bjo.72.7.494. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Augsburger J. J., Gamel J. W., Sardi V. F., Greenberg R. A., Shields J. A., Brady L. W. Enucleation vs cobalt plaque radiotherapy for malignant melanomas of the choroid and ciliary body. Arch Ophthalmol. 1986 May;104(5):655–661. doi: 10.1001/archopht.1986.01050170045019. [DOI] [PubMed] [Google Scholar]
  4. Augsburger J. J., Schroeder R. P., Territo C., Gamel J. W., Shields J. A. Clinical parameters predictive of enlargement of melanocytic choroidal lesions. Br J Ophthalmol. 1989 Nov;73(11):911–917. doi: 10.1136/bjo.73.11.911. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Augsburger J. J., Vrabec T. R. Impact of delayed treatment in growing posterior uveal melanomas. Arch Ophthalmol. 1993 Oct;111(10):1382–1386. doi: 10.1001/archopht.1993.01090100090033. [DOI] [PubMed] [Google Scholar]
  6. Barranco S. C., Romsdahl M. M., Humphrey R. M. The radiation response of human malignant melanoma cells grown in vitro. Cancer Res. 1971 Jun;31(6):830–833. [PubMed] [Google Scholar]
  7. Beitler J. J., McCormick B., Ellsworth R. M., Abramson D. H., Anderson L. L., Loffredo C. Ocular melanoma: total dose and dose rate effects with Co-60 plaque therapy. Radiology. 1990 Jul;176(1):275–278. doi: 10.1148/radiology.176.1.2353101. [DOI] [PubMed] [Google Scholar]
  8. Bentzen S. M., Overgaard J., Thames H. D., Overgaard M., Vejby Hansen P., von der Maase H., Meder J. Clinical radiobiology of malignant melanoma. Radiother Oncol. 1989 Nov;16(3):169–182. doi: 10.1016/0167-8140(89)90017-0. [DOI] [PubMed] [Google Scholar]
  9. Boniuk M. A crisis in the management of patients with choroidal melanoma. Am J Ophthalmol. 1979 Jun;87(6):840–842. doi: 10.1016/0002-9394(79)90367-2. [DOI] [PubMed] [Google Scholar]
  10. Brovkina A. F., Zarubei G. D. Ciliochoroidal melanomas treated with a narrow medical proton beam. Arch Ophthalmol. 1986 Mar;104(3):402–404. doi: 10.1001/archopht.1986.01050150102037. [DOI] [PubMed] [Google Scholar]
  11. Brown G. C., Shields J. A., Sanborn G., Augsburger J. J., Savino P. J., Schatz N. J. Radiation retinopathy. Ophthalmology. 1982 Dec;89(12):1494–1501. doi: 10.1016/s0161-6420(82)34611-4. [DOI] [PubMed] [Google Scholar]
  12. Busse H., Müller R. P., Kroll P. Results of 106Ru/Rh-radiation of choroidal melanomas. Ann Ophthalmol. 1983 Dec;15(12):1146–1149. [PubMed] [Google Scholar]
  13. Char D. H., Castro J. R., Quivey J. M., Chen G. T., Lyman J. T., Stone R. D., Irvine A. R., Barricks M., Crawford J. B., Hilton G. F. Helium ion charged particle therapy for choroidal melanoma. Ophthalmology. 1980 Jun;87(6):565–570. doi: 10.1016/s0161-6420(80)35195-6. [DOI] [PubMed] [Google Scholar]
  14. Char D. H., Quivey J. M., Castro J. R., Kroll S., Phillips T. Helium ions versus iodine 125 brachytherapy in the management of uveal melanoma. A prospective, randomized, dynamically balanced trial. Ophthalmology. 1993 Oct;100(10):1547–1554. doi: 10.1016/s0161-6420(93)31446-6. [DOI] [PubMed] [Google Scholar]
  15. Char D. H., Saunders W., Castro J. R., Quivey J. M., Irvine A. R., Stone R. D., Crawford J. B., Barricks M., Lonn L. I., Hilton G. F. Helium ion therapy for choroidal melanoma. Ophthalmology. 1983 Oct;90(10):1219–1225. doi: 10.1016/s0161-6420(83)34405-5. [DOI] [PubMed] [Google Scholar]
  16. Egan K. M., Gragoudas E. S., Seddon J. M., Glynn R. J., Munzenreider J. E., Goitein M., Verhey L., Urie M., Koehler A. The risk of enucleation after proton beam irradiation of uveal melanoma. Ophthalmology. 1989 Sep;96(9):1377–1383. doi: 10.1016/s0161-6420(89)32738-2. [DOI] [PubMed] [Google Scholar]
  17. Egan K. M., Ryan L. M., Gragoudas E. S. Survival implications of enucleation after definitive radiotherapy for choroidal melanoma: an example of regression on time-dependent covariates. Arch Ophthalmol. 1998 Mar;116(3):366–370. doi: 10.1001/archopht.116.3.366. [DOI] [PubMed] [Google Scholar]
  18. Egan K. M., Seddon J. M., Glynn R. J., Gragoudas E. S., Albert D. M. Epidemiologic aspects of uveal melanoma. Surv Ophthalmol. 1988 Jan-Feb;32(4):239–251. doi: 10.1016/0039-6257(88)90173-7. [DOI] [PubMed] [Google Scholar]
  19. Egger E., Zografos L., Munkel G., Böhringer T., Bercher L., Chamot L. Results of proton radiotherapy for uveal melanomas. Front Radiat Ther Oncol. 1997;30:111–122. doi: 10.1159/000425694. [DOI] [PubMed] [Google Scholar]
  20. Folkman J. Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat Med. 1995 Jan;1(1):27–31. doi: 10.1038/nm0195-27. [DOI] [PubMed] [Google Scholar]
  21. François J. Treatment of malignant melanoma of the choroid by light coagulation. Mod Probl Ophthalmol. 1974;12(0):550–555. [PubMed] [Google Scholar]
  22. Ganley J. P., Comstock G. W. Benign nevi and malignant melanomas of the choroid. Am J Ophthalmol. 1973 Jul;76(1):19–25. doi: 10.1016/0002-9394(73)90003-2. [DOI] [PubMed] [Google Scholar]
  23. Garretson B. R., Robertson D. M., Earle J. D. Choroidal melanoma treatment with iodine 125 brachytherapy. Arch Ophthalmol. 1987 Oct;105(10):1394–1397. doi: 10.1001/archopht.1987.01060100096035. [DOI] [PubMed] [Google Scholar]
  24. Gass J. D. Comparison of prognosis after enucleation vs cobalt 60 irradiation of melanomas. Arch Ophthalmol. 1985 Jul;103(7):916–923. [PubMed] [Google Scholar]
  25. Gass J. D. Observation of suspected choroidal and ciliary body melanomas for evidence of growth prior to enucleation. Ophthalmology. 1980 Jun;87(6):523–528. doi: 10.1016/s0161-6420(80)35200-7. [DOI] [PubMed] [Google Scholar]
  26. Glynn R. J., Seddon J. M., Gragoudas E. S., Egan K. M., Hart L. J. Evaluation of tumor regression and other prognostic factors for early and late metastasis after proton irradiation of uveal melanoma. Ophthalmology. 1989 Oct;96(10):1566–1573. doi: 10.1016/s0161-6420(89)32685-6. [DOI] [PubMed] [Google Scholar]
  27. Gonzalez V. H., Hu L. K., Theodossiadis P. G., Flotte T. J., Gragoudas E. S., Young L. H. Photodynamic therapy of pigmented choroidal melanomas. Invest Ophthalmol Vis Sci. 1995 Apr;36(5):871–878. [PubMed] [Google Scholar]
  28. Gradoudas E. S., Goitein M., Koehler A., Constable I. J., Wagner M. S., Verhey L., Tepper J., Suit H. D., Brockhurst R. J., Schneider R. J. Proton irradiation of choroidal melanomas. Preliminary results. Arch Ophthalmol. 1978 Sep;96(9):1583–1591. doi: 10.1001/archopht.1978.03910060217006. [DOI] [PubMed] [Google Scholar]
  29. Gragoudas E. S., Egan K. M., Arrigg P. G., Seddon J. M., Glynn R. J., Munzenrider J. E. Cataract extraction after proton beam irradiation for malignant melanoma of the eye. Arch Ophthalmol. 1992 Apr;110(4):475–479. doi: 10.1001/archopht.1992.01080160053029. [DOI] [PubMed] [Google Scholar]
  30. Gragoudas E. S., Egan K. M., Saornil M. A., Walsh S. M., Albert D. M., Seddon J. M. The time course of irradiation changes in proton beam-treated uveal melanomas. Ophthalmology. 1993 Oct;100(10):1555–1560. doi: 10.1016/s0161-6420(93)31445-4. [DOI] [PubMed] [Google Scholar]
  31. Gragoudas E. S., Egan K. M., Seddon J. M., Glynn R. J., Walsh S. M., Finn S. M., Munzenrider J. E., Spar M. D. Survival of patients with metastases from uveal melanoma. Ophthalmology. 1991 Mar;98(3):383–390. doi: 10.1016/s0161-6420(91)32285-1. [DOI] [PubMed] [Google Scholar]
  32. Gragoudas E. S., Egan K. M., Seddon J. M., Walsh S. M., Munzenrider J. E. Intraocular recurrence of uveal melanoma after proton beam irradiation. Ophthalmology. 1992 May;99(5):760–766. doi: 10.1016/s0161-6420(92)31900-1. [DOI] [PubMed] [Google Scholar]
  33. Gragoudas E. S., Egan K. M., Walsh S. M., Regan S., Munzenrider J. E., Taratuta V. Lens changes after proton beam irradiation for uveal melanoma. Am J Ophthalmol. 1995 Feb;119(2):157–164. doi: 10.1016/s0002-9394(14)73868-1. [DOI] [PubMed] [Google Scholar]
  34. Gragoudas E. S., Goitein M., Koehler A. M., Verhey L., Tepper J., Suit H. D., Brockhurst R., Constable I. J. Proton irradiation of small choroidal malignant melanomas. Am J Ophthalmol. 1977 May;83(5):665–673. doi: 10.1016/0002-9394(77)90133-7. [DOI] [PubMed] [Google Scholar]
  35. Gragoudas E. S., Goitein M., Verhey L., Munzenreider J., Suit H. D., Koehler A. Proton beam irradiation. An alternative to enucleation for intraocular melanomas. Ophthalmology. 1980 Jun;87(6):571–581. doi: 10.1016/s0161-6420(80)35212-3. [DOI] [PubMed] [Google Scholar]
  36. Gragoudas E. S., Goitein M., Verhey L., Munzenreider J., Urie M., Suit H., Koehler A. Proton beam irradiation of uveal melanomas. Results of 5 1/2-year study. Arch Ophthalmol. 1982 Jun;100(6):928–934. doi: 10.1001/archopht.1982.01030030936007. [DOI] [PubMed] [Google Scholar]
  37. Gragoudas E. S., Seddon J. M., Egan K. M., Glynn R. J., Goitein M., Munzenrider J., Verhey L., Urie M., Koehler A. Metastasis from uveal melanoma after proton beam irradiation. Ophthalmology. 1988 Jul;95(7):992–999. doi: 10.1016/s0161-6420(88)33091-5. [DOI] [PubMed] [Google Scholar]
  38. Gragoudas E. S., Seddon J., Goitein M., Verhey L., Munzenrider J., Urie M., Suit H. D., Blitzer P., Koehler A. Current results of proton beam irradiation of uveal melanomas. Ophthalmology. 1985 Feb;92(2):284–291. doi: 10.1016/s0161-6420(85)34058-7. [DOI] [PubMed] [Google Scholar]
  39. Habermalz H. J., Fischer J. J. Radiation therapy of malignant melanoma: experience with high individual treatment doses. Cancer. 1976 Dec;38(6):2258–2262. doi: 10.1002/1097-0142(197612)38:6<2258::aid-cncr2820380611>3.0.co;2-h. [DOI] [PubMed] [Google Scholar]
  40. Harbour J. W., Char D. H., Kroll S., Quivey J. M., Castro J. Metastatic risk for distinct patterns of postirradiation local recurrence of posterior uveal melanoma. Ophthalmology. 1997 Nov;104(11):1785–1793. doi: 10.1016/s0161-6420(97)30025-6. [DOI] [PubMed] [Google Scholar]
  41. Harbour J. W., Murray T. G., Byrne S. F., Hughes J. R., Gendron E. K., Ehlies F. J., Markoe A. M. Intraoperative echographic localization of iodine 125 episcleral radioactive plaques for posterior uveal melanoma. Retina. 1996;16(2):129–134. doi: 10.1097/00006982-199616020-00008. [DOI] [PubMed] [Google Scholar]
  42. Hill J. C., Sealy R., Shackleton D., Stannard C., Korrubel J., Hering E., Loxton C. Improved iodine-125 plaque design in the treatment of choroidal malignant melanoma. Br J Ophthalmol. 1992 Feb;76(2):91–94. doi: 10.1136/bjo.76.2.91. [DOI] [PMC free article] [PubMed] [Google Scholar]
  43. Jensen O. A. Malignant melanomas of the human uvea: 25-year follow-up of cases in Denmark, 1943--1952. Acta Ophthalmol (Copenh) 1982 Apr;60(2):161–182. doi: 10.1111/j.1755-3768.1982.tb08371.x. [DOI] [PubMed] [Google Scholar]
  44. Karlsson U. L., Augsburger J. J., Shields J. A., Markoe A. M., Brady L. W., Woodleigh R. Recurrence of posterior uveal melanoma after 60Co episcleral plaque therapy. Ophthalmology. 1989 Mar;96(3):382–388. doi: 10.1016/s0161-6420(89)32882-x. [DOI] [PubMed] [Google Scholar]
  45. Kim M. K., Char D. H., Castro J. L., Saunders W. M., Chen G. T., Stone R. D. Neovascular glaucoma after helium ion irradiation for uveal melanoma. Ophthalmology. 1986 Feb;93(2):189–193. doi: 10.1016/s0161-6420(86)33770-9. [DOI] [PubMed] [Google Scholar]
  46. Kindy-Degnan N. A., Char D. H., Castro J. R., Kroll S., Stone R. D., Quivey J. M., Phillips T. L., Irvine A. R. Effect of various doses of radiation for uveal melanoma on regression, visual acuity, complications, and survival. Am J Ophthalmol. 1989 Feb 15;107(2):114–120. doi: 10.1016/0002-9394(89)90208-0. [DOI] [PubMed] [Google Scholar]
  47. Lichter A. S., Lawrence T. S. Recent advances in radiation oncology. N Engl J Med. 1995 Feb 9;332(6):371–379. doi: 10.1056/NEJM199502093320607. [DOI] [PubMed] [Google Scholar]
  48. Lommatzsch P. K., Kirsch I. H. 106Ru/106Rh plaque radiotherapy for malignant melanomas of the choroid. With follow-up results more than 5 years. Doc Ophthalmol. 1988 Mar-Apr;68(3-4):225–238. doi: 10.1007/BF00156429. [DOI] [PubMed] [Google Scholar]
  49. Lommatzsch P. K. beta-Irradiation of choroidal melanoma with 106Ru/106Rh applicators. 16 Years' experience. Arch Ophthalmol. 1983 May;101(5):713–717. doi: 10.1001/archopht.1983.01040010713002. [DOI] [PubMed] [Google Scholar]
  50. MERRIAM G. R., Jr, FOCHT E. F. A clinical study of radiation cataracts and the relationship to dose. Am J Roentgenol Radium Ther Nucl Med. 1957 May;77(5):759–785. [PubMed] [Google Scholar]
  51. Macfaul P. A., Bedford M. A. Ocular complications after therapeutic irradiation. Br J Ophthalmol. 1970 Apr;54(4):237–247. doi: 10.1136/bjo.54.4.237. [DOI] [PMC free article] [PubMed] [Google Scholar]
  52. Meecham W. J., Char D. H., Kroll S., Castro J. R., Blakely E. A. Anterior segment complications after helium ion radiation therapy for uveal melanoma. Radiation cataract. Arch Ophthalmol. 1994 Feb;112(2):197–203. doi: 10.1001/archopht.1994.01090140073026. [DOI] [PubMed] [Google Scholar]
  53. Meyer-Schwickerath G. Photocoagulation of choroidal melanomas. Doc Ophthalmol. 1980 Dec 15;50(1):57–61. doi: 10.1007/BF00161150. [DOI] [PubMed] [Google Scholar]
  54. Moura R. A., McPherson A. R., Easley J. Malignant melanoma of the choroid: treatment with episcleral 198Au plaque and xenon-arc photocoagulation. Ann Ophthalmol. 1985 Feb;17(2):114–125. [PubMed] [Google Scholar]
  55. Oosterhuis J. A., Journée-de Korver H. G., Kakebeeke-Kemme H. M., Bleeker J. C. Transpupillary thermotherapy in choroidal melanomas. Arch Ophthalmol. 1995 Mar;113(3):315–321. doi: 10.1001/archopht.1995.01100030071024. [DOI] [PubMed] [Google Scholar]
  56. Packer S. Iodine-125 radiation of posterior uveal melanoma. Ophthalmology. 1987 Dec;94(12):1621–1626. doi: 10.1016/s0161-6420(87)33241-5. [DOI] [PubMed] [Google Scholar]
  57. Panagopoulos J. A., Svitra P. P., Puliafito C. A., Gragoudas E. S. Photodynamic therapy for experimental intraocular melanoma using chloroaluminum sulfonated phthalocyanine. Arch Ophthalmol. 1989 Jun;107(6):886–890. doi: 10.1001/archopht.1989.01070010908039. [DOI] [PubMed] [Google Scholar]
  58. Parsons J. T., Bova F. J., Fitzgerald C. R., Mendenhall W. M., Million R. R. Radiation optic neuropathy after megavoltage external-beam irradiation: analysis of time-dose factors. Int J Radiat Oncol Biol Phys. 1994 Nov 15;30(4):755–763. doi: 10.1016/0360-3016(94)90346-8. [DOI] [PubMed] [Google Scholar]
  59. Peyman G. A., Raichand M. Full-thickness eye wall resection of choroidal neoplasms. Ophthalmology. 1979 Jun;86(6):1024–1036. doi: 10.1016/s0161-6420(79)35424-0. [DOI] [PubMed] [Google Scholar]
  60. SUIT H. D., GALLAGER H. S. INTACT TUMOR CELLS IN IRRADIATED TISSUE. Arch Pathol. 1964 Dec;78:648–651. [PubMed] [Google Scholar]
  61. Saornil M. A., Egan K. M., Gragoudas E. S., Seddon J. M., Walsh S. M., Albert D. M. Histopathology of proton beam-irradiated vs enucleated uveal melanomas. Arch Ophthalmol. 1992 Aug;110(8):1112–1118. doi: 10.1001/archopht.1992.01080200092031. [DOI] [PubMed] [Google Scholar]
  62. Scotto J., Fraumeni J. F., Jr, Lee J. A. Melanomas of the eye and other noncutaneous sites: epidemiologic aspects. J Natl Cancer Inst. 1976 Mar;56(3):489–491. doi: 10.1093/jnci/56.3.489. [DOI] [PubMed] [Google Scholar]
  63. Seddon J. M., Gragoudas E. S., Albert D. M. Ciliary body and choroidal melanomas treated by proton beam irradiation. Histopathologic study of eyes. Arch Ophthalmol. 1983 Sep;101(9):1402–1408. doi: 10.1001/archopht.1983.01040020404014. [DOI] [PubMed] [Google Scholar]
  64. Seddon J. M., Gragoudas E. S., Egan K. M., Glynn R. J., Howard S., Fante R. G., Albert D. M. Relative survival rates after alternative therapies for uveal melanoma. Ophthalmology. 1990 Jun;97(6):769–777. doi: 10.1016/s0161-6420(90)32512-5. [DOI] [PubMed] [Google Scholar]
  65. Seddon J. M., Gragoudas E. S., Egan K. M., Glynn R. J., Munzenrider J. E., Austin-Seymour M., Goitein M., Verhey L., Urie M., Koehler A. Uveal melanomas near the optic disc or fovea. Visual results after proton beam irradiation. Ophthalmology. 1987 Apr;94(4):354–361. doi: 10.1016/s0161-6420(87)33439-6. [DOI] [PubMed] [Google Scholar]
  66. Seddon J. M., Gragoudas E. S., Glynn R. J., Egan K. M., Albert D. M., Blitzer P. H. Host factors, UV radiation, and risk of uveal melanoma. A case-control study. Arch Ophthalmol. 1990 Sep;108(9):1274–1280. doi: 10.1001/archopht.1990.01070110090031. [DOI] [PubMed] [Google Scholar]
  67. Seddon J. M., Gragoudas E. S., Polivogianis L., Hsieh C. C., Egan K. M., Goitein M., Verhey L., Munzenrider J., Austin-Seymour M., Urie M. Visual outcome after proton beam irradiation of uveal melanoma. Ophthalmology. 1986 May;93(5):666–674. doi: 10.1016/s0161-6420(86)33700-x. [DOI] [PubMed] [Google Scholar]
  68. Seddon J., Gragoudas E., Egan K., Polivogianis L., Finn S., Albert D. Standardized data collection and coding in eye disease epidemiology: the Uveal Melanoma Data System. Ophthalmic Surg. 1991 Mar;22(3):127–136. [PubMed] [Google Scholar]
  69. Seigel D., Myers M., Ferris F., 3rd, Steinhorn S. C. Survival rates after enucleation of eyes with malignant melanoma. Am J Ophthalmol. 1979 Jun;87(6):761–765. doi: 10.1016/0002-9394(79)90349-0. [DOI] [PubMed] [Google Scholar]
  70. Shields C. L., Shields J. A., DePotter P., Kheterpal S. Transpupillary thermotherapy in the management of choroidal melanoma. Ophthalmology. 1996 Oct;103(10):1642–1650. doi: 10.1016/s0161-6420(96)30451-x. [DOI] [PubMed] [Google Scholar]
  71. Shields C. L., Shields J. A., Kiratli H., De Potter P., Cater J. R. Risk factors for growth and metastasis of small choroidal melanocytic lesions. Ophthalmology. 1995 Sep;102(9):1351–1361. [PubMed] [Google Scholar]
  72. Shields J. A., Augsburger J. J., Brady L. W., Day J. L. Cobalt plaque therapy of posterior uveal melanomas. Ophthalmology. 1982 Oct;89(10):1201–1207. doi: 10.1016/s0161-6420(82)34658-8. [DOI] [PubMed] [Google Scholar]
  73. Stallard H. B. Malignant melanoblastoma of the choroid. Bibl Ophthalmol. 1968;75:16–38. [PubMed] [Google Scholar]
  74. Stallard H. B. Radiotherapy for malignant melanoma of the choroid. Br J Ophthalmol. 1966 Mar;50(3):147–155. doi: 10.1136/bjo.50.3.147. [DOI] [PMC free article] [PubMed] [Google Scholar]
  75. Suit H., Urie M. Proton beams in radiation therapy. J Natl Cancer Inst. 1992 Feb 5;84(3):155–164. doi: 10.1093/jnci/84.3.155. [DOI] [PubMed] [Google Scholar]
  76. Tse D. T., Dutton J. J., Weingeist T. A., Hermsen V. M., Kersten R. C. Hematoporphyrin photoradiation therapy for intraocular and orbital malignant melanoma. Arch Ophthalmol. 1984 Jun;102(6):833–838. doi: 10.1001/archopht.1984.01040030653011. [DOI] [PubMed] [Google Scholar]
  77. Tucker M. A., Shields J. A., Hartge P., Augsburger J., Hoover R. N., Fraumeni J. F., Jr Sunlight exposure as risk factor for intraocular malignant melanoma. N Engl J Med. 1985 Sep 26;313(13):789–792. doi: 10.1056/NEJM198509263131305. [DOI] [PubMed] [Google Scholar]
  78. Vrabec T. R., Augsburger J. J., Gamel J. W., Brady L. W., Hernandez C., Woodleigh R. Impact of local tumor relapse on patient survival after cobalt 60 plaque radiotherapy. Ophthalmology. 1991 Jun;98(6):984–988. doi: 10.1016/s0161-6420(91)32193-6. [DOI] [PubMed] [Google Scholar]
  79. Wilkes S. R., Gragoudas E. S. Regression patterns of uveal melanomas after proton beam irradiation. Ophthalmology. 1982 Jul;89(7):840–844. doi: 10.1016/s0161-6420(82)34731-4. [DOI] [PubMed] [Google Scholar]
  80. Wingo P. A., Tong T., Bolden S. Cancer statistics, 1995. CA Cancer J Clin. 1995 Jan-Feb;45(1):8–30. doi: 10.3322/canjclin.45.1.8. [DOI] [PubMed] [Google Scholar]
  81. Withers H. R. Biological basis of radiation therapy for cancer. Lancet. 1992 Jan 18;339(8786):156–159. doi: 10.1016/0140-6736(92)90218-r. [DOI] [PubMed] [Google Scholar]
  82. Young L. H., Howard M. A., Hu L. K., Kim R. Y., Gragoudas E. S. Photodynamic therapy of pigmented choroidal melanomas using a liposomal preparation of benzoporphyrin derivative. Arch Ophthalmol. 1996 Feb;114(2):186–192. doi: 10.1001/archopht.1996.01100130180013. [DOI] [PubMed] [Google Scholar]
  83. Zimmerman L. E., McLean I. W., Foster W. D. Does enucleation of the eye containing a malignant melanoma prevent or accelerate the dissemination of tumour cells. Br J Ophthalmol. 1978 Jun;62(6):420–425. doi: 10.1136/bjo.62.6.420. [DOI] [PMC free article] [PubMed] [Google Scholar]
  84. Zografos L., Gailloud C., Perret C., Uffer S., Raimondi S., Chamot L., Carrel S., Greiner R. Rapport sur le traitement conservateur des mélanomes de l'uvée à la clinique ophtalmologique universitaire de Lausanne. Klin Monbl Augenheilkd. 1988 May;192(5):572–578. doi: 10.1055/s-2008-1050181. [DOI] [PubMed] [Google Scholar]

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