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Transactions of the American Ophthalmological Society logoLink to Transactions of the American Ophthalmological Society
. 1987;85:238–253.

A prospective, randomized study of 5-fluorouracil and filtration surgery.

J M Ruderman 1, D B Welch 1, M F Smith 1, D E Shoch 1
PMCID: PMC1298776  PMID: 3447334

Abstract

Our study shows that use of a small dose of subconjunctival 5-FU provides significantly lower postoperative intraocular pressure than does no antimetabolite treatment. Morphology of the postoperative blebs suggests that increased filtration results in lower intraocular pressure in the 5-FU group. Corneal epithelial defects were as common with a low dose as with higher doses previously described.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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