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Journal of Orthopaedic Surgery and Research logoLink to Journal of Orthopaedic Surgery and Research
. 2026 Mar 17;21:197. doi: 10.1186/s13018-026-06812-5

Correction: METTL3 accelerates staphylococcal protein A (SpA)-induced osteomyelitis progression by regulating m6A methylation-modified miR-320a

Ding Gao 1, Jian Shi 2, Siyu Lu 2, Junyi Li 2,3, Kehan Lv 2,3, Yongqing Xu 2,✉, Muguo Song 2,3,✉
PMCID: PMC12994249  PMID: 41845366

Correction to: Journal of Orthopaedic Surgery and Research (2024) 19:729 10.1186/s13018-024-05164-2

In this article [1], the ARS staining image originally representing the SpA group was mistakenly placed in the SpA + NC-kd panel, the Fig. 2c was incorrectly displayed, the correct Fig. 2c was shown below:

Incorrect Figure 2:

Fig. 2.

Fig. 2

Silencing of METTL3 reverses the effects of SpA on osteogenic differentiation, oxidative stress and inflammatory responses in hBMSCs. A The knockdown efficiency of silencing METTL3 in hBMSCs was examined by RT-qPCR. B Western blot analysis was performed to measure the expression of Runx2, OCN and ALP in hBMSCs of Control, SpA, SpA+NC-kd and SpA+METTL3-kd groups. C–D The calcium deposition was detected by ARS staining in Control, SpA, SpA+NC-kd and SpA+METTL3-kd groups (scale bars, 50 μm). E The protein levels of SOD, CAT and GSH in hBMSCs of Control, SpA, SpA+NC-kd and SpA+METTL3-kd groups were measured by ELISA. F The expression of IL-1β, IL-6 and TNF-α in Control, SpA, SpA+NC-kd and SpA+METTL3-kd groups of hBMSCs was assessed by ELISA. *p<0.05, **p < 0.01, ***p < 0.005

Correct Figure 2:

Fig. 2.

Fig. 2

Silencing of METTL3 reverses the effects of SpA on osteogenic differentiation, oxidative stress and inflammatory responses in hBMSCs. A The knockdown efficiency of silencing METTL3 in hBMSCs was examined by RT-qPCR. B Western blot analysis was performed to measure the expression of Runx2, OCN and ALP in hBMSCs of Control, SpA, SpA+NC-kd and SpA+METTL3-kd groups. C–D The calcium deposition was detected by ARS staining in Control, SpA, SpA+NC-kd and SpA+METTL3-kd groups (scale bars, 50 μm). E The protein levels of SOD, CAT and GSH in hBMSCs of Control, SpA, SpA+NC-kd and SpA+METTL3-kd groups were measured by ELISA. F The expression of IL-1β, IL-6 and TNF-α in Control, SpA, SpA+NC-kd and SpA+METTL3-kd groups of hBMSCs was assessed by ELISA. *p < 0.05, **p < 0.01, ***p < 0.005

The authors regret this error and any confusion it may have caused.

Footnotes

Publisher’s note

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Contributor Information

Yongqing Xu, Email: XuYongqing_TG@163.com.

Muguo Song, Email: ansen82@163.com.

References

  • 1.Gao D, Shi J, Lu S, Li J, Lv K, Xu Y, Song M. METTL3 accelerates staphylococcal protein A (SpA)-induced osteomyelitis progression by regulating m6A methylation-modified miR-320a. J Orthop Surg Res. 2024;19(1):729. [DOI] [PMC free article] [PubMed] [Google Scholar]

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