There was a mistake in Figure 1 as published. A symbol indicating statistical significance in Figure 1E was positioned incorrectly. The corrected Figure 1 appears below.
Figure 1.
Abnormal steroids in OLP plasma and their functions. (A–E). Steroids in plasma from healthy donors (n=4) and OLP patients (n=4) were determined by LC-MS/MS, and the results of the top 20 metabolites by differential folds were shown as bar chart (A); The results of the top 10 metabolites with the highest FC value were shown in the Volcano diagram (B); Clustering heat map (C); The heat map of correlation between differential metabolites (D); The violin diagram (E) of differential metabolites. (F–I). Functional annotation and enrichment analysis of differential metabolites were performed. The bar chart of KEGG classification with the proportion of differential metabolites assigned to each pathway (F), the bubble plots of KEGG functional enrichment (G), differential abundance scores (H) and HMDB enrichment analysis (I). (J–L). Flow cytometry was used to determine the levels of cellular cholesterol metabolism regulatory axis SREBP2-LXR in primary T cells treated/untreated with 7-ketocholesterol (J), and the mean fluorescence intensity (MFI) of LXR (K) and SREBP2 (L) were calculated. Data were presented as mean ± SEM. *p < 0.05, **p < 0.01, 7KC, 7-Ketocholesterol.
The original version of this article has been updated.
Footnotes
Edited and reviewed by: Lei Hu, Capital Medical University, China
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