Table 4.
Correlation of several genotypes of ERCC4 (rs6498486) with breast cancer in cases and controls
| Polymorphism | Genotype | Cases (N=150) (%) | Controls (N=150) (%) | OR (95 % CI) | P- Value |
|---|---|---|---|---|---|
| ERCC4 gene (rs6498486) | AA | 12 (8%) | 48 (32%) | - | - |
| AC | 106 (70.66%) | 84 (56%) | 5.0476 (2.5207–10.1075.5207.1075) | 0.0001 | |
| CC | 32 (21.33%) | 18 (12%) | 7.1111 (3.0196–16.7464.0196.7464) | 0.0001 | |
| AC+CC | 138 (92%) | 102 (68%) | 5.4118 (2.7351–10.7078.7351.7078) | 0.0001 | |
| A | 130 (43.33%) | 180 (60%) | - | - | |
| C | 170 (56.66%) | 120 (40%) | 1.9615 (1.4175–2.7143.4175.7143) | 0.0001 |
p<0.05 was considered statistically significant