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Acta Neuropathologica Communications logoLink to Acta Neuropathologica Communications
. 2026 Mar 27;14:71. doi: 10.1186/s40478-026-02278-y

Retraction Note: Combination of alpha-synuclein immunotherapy with anti-inflammatory treatment in a transgenic mouse model of multiple system atrophy

Elvira Valera 1, Brian Spencer 1, Jerel A Fields 1, Ivy Trinh 1, Anthony Adame 1, Michael Mante 1, Edward Rockenstein 1, Paula Desplats 1,2, Eliezer Masliah 1,2,
PMCID: PMC13023175  PMID: 41896929

Retraction Note to: Acta Neuropathologica Communications (2017) 5:2 10.1186/s40478-016-0409-1

The Editors-in-Chief have retracted this article. After publication, concerns were raised regarding some of the images presented in the figures, specifically:

  • Fig. 1A MBP-α-syn-tg LV-control Vehicle and Lenalidomide images appear to overlap;

  • Fig. 1C Non-tg LV-control Vehicle and LV-CD5-D5-apoB Vehicle images appear to overlap;

  • Fig. 1D Non-tg LV-control Vehicle and Lenalidomide images appear to overlap;

  • Fig. 2B Non-th LV-control Vehicle and Lenalidomide, and LV-CD5-D5-apoB Vehicle images appear to overlap;

  • Fig. S1a LV-CD5-D5-apoB Vehicle MBP-α-syn-tg image appears to have duplicated patterns;

  • Fig. S2a LV-CD5-D5-apoB Vehicle Non-tg image appears to have duplicated patterns.

The Editors-in-Chief therefore no longer have confidence in the presented data.

Elezier Masliah has not explicitly stated whether they agree with this retraction. Edward Rockenstein is deceased. The other authors have not responded to any correspondence from the editor or publisher about this retraction.

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