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. 1997 Oct;167(4):269–275.

Memory, thinking, and aging. What we know about what we know.

L Teri 1, S M McCurry 1, R G Logsdon 1
PMCID: PMC1304543  PMID: 9348759

Abstract

Cognition is the foundation that underlies all daily activities, from the most basic to the most complex. Successful aging depends, in large part, on maintaining a level of cognitive ability that allows a person to interact effectively and appropriately with the environment. In the following article we provide an overview of the effects of aging on cognition; discuss physical, social, and psychological factors that have been shown to influence cognition in old age; and review current literature on interventions that may optimize successful cognitive aging. We conclude with a discussion of abnormal cognitive aging and review current research on risk factors and treatments of Alzheimer's disease and other dementing illnesses.

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Selected References

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  1. Albert M. S., Jones K., Savage C. R., Berkman L., Seeman T., Blazer D., Rowe J. W. Predictors of cognitive change in older persons: MacArthur studies of successful aging. Psychol Aging. 1995 Dec;10(4):578–589. doi: 10.1037//0882-7974.10.4.578. [DOI] [PubMed] [Google Scholar]
  2. Andrewes D. G., Kinsella G., Murphy M. Using a memory handbook to improve everyday memory in community-dwelling older adults with memory complaints. Exp Aging Res. 1996 Jul-Sep;22(3):305–322. doi: 10.1080/03610739608254013. [DOI] [PubMed] [Google Scholar]
  3. Berkman L. F., Seeman T. E., Albert M., Blazer D., Kahn R., Mohs R., Finch C., Schneider E., Cotman C., McClearn G. High, usual and impaired functioning in community-dwelling older men and women: findings from the MacArthur Foundation Research Network on Successful Aging. J Clin Epidemiol. 1993 Oct;46(10):1129–1140. doi: 10.1016/0895-4356(93)90112-e. [DOI] [PubMed] [Google Scholar]
  4. Brandtstädter J., Renner G. Tenacious goal pursuit and flexible goal adjustment: explication and age-related analysis of assimilative and accommodative strategies of coping. Psychol Aging. 1990 Mar;5(1):58–67. doi: 10.1037//0882-7974.5.1.58. [DOI] [PubMed] [Google Scholar]
  5. Caprio-Prevette M. D., Fry P. S. Memory enhancement program for community-based older adults: development and evaluation. Exp Aging Res. 1996 Jul-Sep;22(3):281–303. doi: 10.1080/03610739608254012. [DOI] [PubMed] [Google Scholar]
  6. Farmer M. E., Kittner S. J., Rae D. S., Bartko J. J., Regier D. A. Education and change in cognitive function. The Epidemiologic Catchment Area Study. Ann Epidemiol. 1995 Jan;5(1):1–7. doi: 10.1016/1047-2797(94)00047-w. [DOI] [PubMed] [Google Scholar]
  7. Garfein A. J., Herzog A. R. Robust aging among the young-old, old-old, and oldest-old. J Gerontol B Psychol Sci Soc Sci. 1995 Mar;50(2):S77–S87. doi: 10.1093/geronb/50b.2.s77. [DOI] [PubMed] [Google Scholar]
  8. Geldmacher D. S., Whitehouse P. J., Jr Differential diagnosis of Alzheimer's disease. Neurology. 1997 May;48(5 Suppl 6):S2–S9. doi: 10.1212/wnl.48.5_suppl_6.2s. [DOI] [PubMed] [Google Scholar]
  9. Glass T. A., Seeman T. E., Herzog A. R., Kahn R., Berkman L. F. Change in productive activity in late adulthood: MacArthur studies of successful aging. J Gerontol B Psychol Sci Soc Sci. 1995 Mar;50(2):S65–S76. doi: 10.1093/geronb/50b.2.s65. [DOI] [PubMed] [Google Scholar]
  10. Hayslip B., Jr, Maloy R. M., Kohl R. Long-term efficacy of fluid ability interventions with older adults. J Gerontol B Psychol Sci Soc Sci. 1995 May;50(3):P141–P149. doi: 10.1093/geronb/50b.3.p141. [DOI] [PubMed] [Google Scholar]
  11. Horn J. L., Cattell R. B. Age differences in fluid and crystallized intelligence. Acta Psychol (Amst) 1967;26(2):107–129. doi: 10.1016/0001-6918(67)90011-x. [DOI] [PubMed] [Google Scholar]
  12. Lachman M. E., Weaver S. L., Bandura M., Elliott E., Lewkowicz C. J. Improving memory and control beliefs through cognitive restructuring and self-generated strategies. J Gerontol. 1992 Sep;47(5):P293–P299. doi: 10.1093/geronj/47.5.p293. [DOI] [PubMed] [Google Scholar]
  13. Leibovici D., Ritchie K., Ledésert B., Touchon J. Does education level determine the course of cognitive decline? Age Ageing. 1996 Sep;25(5):392–397. doi: 10.1093/ageing/25.5.392. [DOI] [PubMed] [Google Scholar]
  14. Lendon C. L., Ashall F., Goate A. M. Exploring the etiology of Alzheimer disease using molecular genetics. JAMA. 1997 Mar 12;277(10):825–831. [PubMed] [Google Scholar]
  15. Neely A. S., Bäckman L. Effects of multifactorial memory training in old age: generalizability across tasks and individuals. J Gerontol B Psychol Sci Soc Sci. 1995 May;50(3):P134–P140. doi: 10.1093/geronb/50b.3.p134. [DOI] [PubMed] [Google Scholar]
  16. Neely A. S., Bäckman L. Long-term maintenance of gains from memory training in older adults: two 3 1/2-year follow-up studies. J Gerontol. 1993 Sep;48(5):P233–P237. doi: 10.1093/geronj/48.5.p233. [DOI] [PubMed] [Google Scholar]
  17. Nolan K. A., Blass J. P. Preventing cognitive decline. Clin Geriatr Med. 1992 Feb;8(1):19–34. [PubMed] [Google Scholar]
  18. Poon L. W., Martin P., Clayton G. M., Messner S., Noble C. A., Johnson M. A. The influences of cognitive resources on adaptation and old age. Int J Aging Hum Dev. 1992;34(1):31–46. doi: 10.2190/T3FB-V3XE-L057-1WM3. [DOI] [PubMed] [Google Scholar]
  19. Rapp P. R., Amaral D. G. Individual differences in the cognitive and neurobiological consequences of normal aging. Trends Neurosci. 1992 Sep;15(9):340–345. doi: 10.1016/0166-2236(92)90051-9. [DOI] [PubMed] [Google Scholar]
  20. Rocca W. A. Frequency, distribution, and risk factors for Alzheimer's disease. Nurs Clin North Am. 1994 Mar;29(1):101–111. [PubMed] [Google Scholar]
  21. Rowe J. W., Kahn R. L. Human aging: usual and successful. Science. 1987 Jul 10;237(4811):143–149. doi: 10.1126/science.3299702. [DOI] [PubMed] [Google Scholar]
  22. Salthouse T. A. Age-related differences in basic cognitive processes: implications for work. Exp Aging Res. 1994 Oct-Dec;20(4):249–255. doi: 10.1080/03610739408253974. [DOI] [PubMed] [Google Scholar]
  23. Sano M., Ernesto C., Thomas R. G., Klauber M. R., Schafer K., Grundman M., Woodbury P., Growdon J., Cotman C. W., Pfeiffer E. A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease. The Alzheimer's Disease Cooperative Study. N Engl J Med. 1997 Apr 24;336(17):1216–1222. doi: 10.1056/NEJM199704243361704. [DOI] [PubMed] [Google Scholar]
  24. Schaie K. W. The hazards of cognitive aging. Gerontologist. 1989 Aug;29(4):484–493. doi: 10.1093/geront/29.4.484. [DOI] [PubMed] [Google Scholar]
  25. Schellenberg G. D., Bird T. D., Wijsman E. M., Orr H. T., Anderson L., Nemens E., White J. A., Bonnycastle L., Weber J. L., Alonso M. E. Genetic linkage evidence for a familial Alzheimer's disease locus on chromosome 14. Science. 1992 Oct 23;258(5082):668–671. doi: 10.1126/science.1411576. [DOI] [PubMed] [Google Scholar]
  26. Sherwin B. B. Estrogen effects on cognition in menopausal women. Neurology. 1997 May;48(5 Suppl 7):S21–S26. doi: 10.1212/wnl.48.5_suppl_7.21s. [DOI] [PubMed] [Google Scholar]
  27. Stigsdotter A., Bäckman L. Multifactorial memory training with older adults: how to foster maintenance of improved performance. Gerontology. 1989;35(5-6):260–267. doi: 10.1159/000213035. [DOI] [PubMed] [Google Scholar]
  28. Strawbridge W. J., Cohen R. D., Shema S. J., Kaplan G. A. Successful aging: predictors and associated activities. Am J Epidemiol. 1996 Jul 15;144(2):135–141. doi: 10.1093/oxfordjournals.aje.a008900. [DOI] [PubMed] [Google Scholar]
  29. Teri L., Logsdon R. G., Uomoto J., McCurry S. M. Behavioral treatment of depression in dementia patients: a controlled clinical trial. J Gerontol B Psychol Sci Soc Sci. 1997 Jul;52(4):P159–P166. doi: 10.1093/geronb/52b.4.p159. [DOI] [PubMed] [Google Scholar]
  30. Traber M. G., Sies H. Vitamin E in humans: demand and delivery. Annu Rev Nutr. 1996;16:321–347. doi: 10.1146/annurev.nu.16.070196.001541. [DOI] [PubMed] [Google Scholar]
  31. Verhaeghen P., Marcoen A., Goossens L. Improving memory performance in the aged through mnemonic training: a meta-analytic study. Psychol Aging. 1992 Jun;7(2):242–251. doi: 10.1037//0882-7974.7.2.242. [DOI] [PubMed] [Google Scholar]
  32. Zec R. F. The neuropsychology of aging. Exp Gerontol. 1995 May-Aug;30(3-4):431–442. doi: 10.1016/0531-5565(94)00066-c. [DOI] [PubMed] [Google Scholar]

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